Author details

Full Name

Rameen Beroukhim

Affiliation

ORCID

Career Start Year

1995

Papers

221

H Index

100

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37380777	Cancer aneuploidies are shaped primarily by effects on tumour fitness.	Nature	2023
37722087	Inaugural Results of the Individualized Screening Trial of Innovative Glioblastoma Therapy: A Phase II Platform Trial for Newly Diagnosed Glioblastoma Using Bayesian Adaptive Randomization.	J Clin Oncol	2023
37873277	Double-strand break repair-associated intragenic deletions and tandem duplications suggest the architecture of the repair replication fork.	bioRxiv	2023
36780194	ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma.	Clin Cancer Res	2023
36697832	Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.	Nature	2023
34878541	Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making.	Neuro Oncol	2022
36040810	VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system.	JCI Insight	2022
36040167	Tangent normalization for somatic copy-number inference in cancer genome analysis.	Bioinformatics	2022
35836307	The genomic landscape of dysembryoplastic neuroepithelial tumours and a comprehensive analysis of recurrent cases.	Neuropathol Appl Neurobiol	2022
35764888	Structural variations in cancer and the 3D genome.	Nat Rev Cancer	2022
35821277	Publisher Correction: DNA-based copy number analysis confirms genomic evolution of PDX models.	NPJ Precis Oncol	2022
35943799	Patterns of structural variation define prostate cancer across disease states.	JCI Insight	2022
35788723	Structural variants shape driver combinations and outcomes in pediatric high-grade glioma.	Nat Cancer	2022
34015129	Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results.	Neuro Oncol	2022
34984433	Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.	Neuro Oncol	2022
34508644	A molecularly integrated grade for meningioma.	Neuro Oncol	2022
35190823	Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma.	Clin Cancer Res	2022
35105861	PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.	Nat Commun	2022
33247715	Quantification of aneuploidy in targeted sequencing data using ASCETS.	Bioinformatics	2021
33961797	TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.	Mol Cell	2021
33626341	Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway.	Cell Rep	2021
34261517	Haplotype-resolved germline and somatic alterations in renal medullary carcinomas.	Genome Med	2021
33505028	Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.	Nature	2021
33982016	Integrative modeling identifies genetic ancestry-associated molecular correlates in human cancer.	STAR Protoc	2021
33007263	Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.	Cell	2020
32433464	Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.	Nat Commun	2020
32322066	Mechanisms and therapeutic implications of hypermutation in gliomas.	Nature	2020
32025000	Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model.	Nat Genet	2020
32424350	Cas9 activates the p53 pathway and selects for p53-inactivating mutations.	Nat Genet	2020
32348107	Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids.	ACS Chemical Biology	2020
31935369	Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.	Cancer Cell	2020
32381545	MR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma.	AJNR Am J Neuroradiol	2020
33259802	Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.	Cell	2020
32587373	Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations.	Nat Genet	2020
33234154	CloneSifter: enrichment of rare clones from heterogeneous cell populations.	BMC Biology	2020
30777879	MCL1 and DEDD Promote Urothelial Carcinoma Progression.	Mol Cancer Res	2019
31748746	Longitudinal molecular trajectories of diffuse glioma in adults.	Nature	2019
30442683	<i>PIK3CA</i> Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma.	Clin Cancer Res	2019
30578414	Genomic evolution of cancer models: perils and opportunities.	Nat Rev Cancer	2019
30872525	Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.	Science	2019
30860482	Renal medullary carcinomas depend upon <i>SMARCB1</i> loss and are sensitive to proteasome inhibition.	Elife	2019
31444999	Phase II trial of ponatinib in patients with bevacizumab-refractory glioblastoma.	Cancer Medicine	2019
31427603	Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.	Nat Commun	2019
31160565	Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma.	Nat Commun	2019
29848573	Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome.	Clin Cancer Res	2018
29925010	The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.	Cell Rep	2018
30537514	Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.	Cancer Cell	2018
30093730	Author Correction: Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition.	Nat Med	2018
29955181	Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29955182	Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018