Author details

Full Name

John M C Connell

Affiliation

ORCID

Career Start Year

1981

Papers

359

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35783032	Corrigendum for health-related quality of life and hospitalizations in chronic thromboembolic pulmonary hypertension versus idiopathic pulmonary arterial hypertension: And analysis from the Pulmonary Hypertension Association Registry.	Pulmonary Circulation	2022
31127295	A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.	Hum Mol Genet	2019
29455858	A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.	Am J Hum Genet	2018
30429575	Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
29912962	Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.	PLoS One	2018
30224653	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
29748316	Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.	Circ Genom Precis Med	2018
28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Nat Genet	2017
28951623	Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Nat Genet	2017
28852406	Regulation of Corticosteroidogenic Genes by MicroRNAs.	International Journal of Endocrinology	2017
28739976	Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.	Hypertension	2017
29030403	New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475â¿¿000 Individuals.	Circ Cardiovasc Genet	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017
28272372	ACTH and Polymorphisms at Steroidogenic Loci as Determinants of Aldosterone Secretion and Blood Pressure.	International Journal of Molecular Sciences	2017
27618447	Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.	Nat Genet	2016
26902494	Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus.	Hypertension	2016
27466198	Analysis with the exome array identifies multiple new independent variants in lipid loci.	Hum Mol Genet	2016
27618452	The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.	Nat Genet	2016
26082470	Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects.	Hum Mol Genet	2015
25413366	Plasma steroid profiling and response to trophins to illustrate intra-adrenal dynamics.	Journal of Endocrinology	2015
26053152	Characterization of the molecular genetic pathology in patients with 11Î²-hydroxylase deficiency.	Clinical Endocrinology	2015
26131930	Directional dominance on stature and cognition inÂ diverse human populations.	Nature	2015
25999743	Cardiac tissue engineering and regeneration using cell-based therapy.	Stem Cells and Cloning: Advances and Applications	2015
24560520	Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.	Am J Hum Genet	2014
30743758	Progress in the identification of responsible genes and molecular mechanisms in primary aldosteronism.		2014
24151953	Characterization of warm saline-enhanced radiofrequency ablation lesions in the infarcted porcine ventricular myocardium.	Journal of Cardiovascular Electrophysiology	2014
24840812	Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe.	J Clin Endocrinol Metab	2014
23711645	Ischemic mitral regurgitation: mechanisms, intraoperative echocardiographic evaluation, and surgical considerations.	Anesthesiology Clinics	2013
22901318	An audit of growth hormone replacement for GH-deficient adults in Scotland.	Clinical Endocrinology	2013
23937567	Quantitative variation in plasma angiotensin-I converting enzyme activity shows allelic heterogeneity in the ABO blood group locus.	Annals of Human Genetics	2013
23836801	MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex.	Hypertension	2013
23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Nat Genet	2013
23150505	Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.	Hypertension	2013
23469866	Assessment of the accuracy and reproducibility of adrenal volume measurements using MRI and its relationship with corticosteroid phenotype: a normal volunteer pilot study.	Clinical Endocrinology	2013
23212553	Effect of cardiac stem cells on left-ventricular remodeling in a canine model of chronic myocardial infarction.	Circulation: Heart Failure	2013
23413088	Urinary sodium excretion is the main determinant of mineralocorticoid excretion rates in patients with chronic kidney disease.	Nephrology Dialysis Transplantation	2013
21767599	Non-adrenal synthesis of aldosterone: a reality check.	Molecular and Cellular Endocrinology	2012
22652909	APEX1 regulation of aldosterone synthase gene transcription is disrupted by a common polymorphism in humans.	Circulation Research	2012
22397469	Urinary corticosteroid excretion predicts left ventricular mass and proteinuria in chronic kidney disease.	Clinical Science	2012
22422767	Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites.	Human Molecular Genetics	2012
23019275	Demonstration of blood pressure-independent noninfarct myocardial fibrosis in primary aldosteronism: a cardiac magnetic resonance imaging study.	Circulation: Cardiovascular Imaging	2012
23063622	Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.	Am J Hum Genet	2012
21858044	Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness.	PLoS ONE	2011
21164264	Role of genetic variation in regulation of aldosterone biosynthesis.	Endocrine Development	2011
21330601	Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies.	Circulation Research	2011
21455728	AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study.	Diabetologia	2011
21451421	A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism.	J Hypertens	2011
21402901	Common variation at the 11-Î² hydroxysteroid dehydrogenase type 1 gene is associated with left ventricular mass.	Circulation: Cardiovascular Genetics	2011
20624770	Association between proteinuria and left ventricular mass index: a cardiac MRI study in patients with chronic kidney disease.	Nephrology Dialysis Transplantation	2011
21909115	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.	Nature	2011