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Author Details

Mian M Alauddin
The University of Texas MD Anderson Cancer Center
1991
85
29
PMIDPaper TitleJournal TitlePublished Year
37214681Evaluation of <sup>89</sup>Zr-Labeled Anti-PD-L1 Monoclonal Antibodies Using DFO and Novel HOPO Analogues as Chelating Agents for Immuno-PET.ACS Omega2023
32003655Advances in Immuno-PET for the Detection of Cancer and Assessment of Response to Therapy.Curr Med Chem2021
31425908Novel derivatives of anaplastic lymphoma kinase inhibitors: Synthesis, radiolabeling, and preliminary biological studies of fluoroethyl analogues of crizotinib, alectinib, and ceritinib.Eur J Med Chem2019
29189119Journey of 2'-deoxy-2'-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU): from Antiviral Drug to PET Imaging Agent.Curr Med Chem2018
29490919MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques.Proc Natl Acad Sci U S A2018
26853088Synthesis of a [(18)F]-labeled ceritinib analogue for positron emission tomography of anaplastic lymphoma kinase, a receptor tyrosine kinase, in lung cancer.J Labelled Comp Radiopharm2016
26272062Integrating Murine and Clinical Trials with Cabozantinib to Understand Roles of MET and VEGFR2 as Targets for Growth Inhibition of Prostate Cancer.Clin Cancer Res2016
27791181Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer.Proc Natl Acad Sci U S A2016
27246312Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography.Mol Imaging Biol2016
26295468Current and Future Trends in Early Detection of Pancreatic Cancer: Molecular Targets and PET Probes.Curr Med Chem2015
26244761Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain.PLoS One2015
24280068Imatinib analogs as potential agents for PET imaging of Bcr-Abl and c-KIT expression at a kinase level.Bioorg Med Chem2014
25189831Preliminary evaluation of 1'-[(18)F]fluoroethyl-β-D-lactose ([(18)F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts.Nucl Med Biol2014
24508409Optimization of precursor synthesis, formulation and stability of 1'-[18F]fluoroethyl-β-D-lactose ([18F]FEL) for preclinical studies in detection of pancreatic cancer.Nucl Med Biol2014
24675806Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents.Sci Rep2014
22875335Monitoring therapy with MEK inhibitor U0126 in a novel Wilms tumor model in Wt1 knockout Igf2 transgenic mice using 18F-FDG PET with dual-contrast enhanced CT and MRI: early metabolic response without inhibition of tumor growth.Mol Imaging Biol2013
24285438An improved synthesis of 1'-[18F]fluoroethyl-β-D-lactose ([18F]-FEL) for positron emission tomography imaging of pancreatic cancer.J Labelled Comp Radiopharm2013
24285330Nucleoside-based probes for imaging tumor proliferation using positron emission tomography.J Labelled Comp Radiopharm2013
23969084Monitoring tumor response with [18F]FMAU in a sarcoma-bearing mouse model after liposomal vinorelbine treatment.Nucl Med Biol2013
22995777Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with ¹⁸F-FAHA.Neuroimage2013
21437735Pharmacokinetics, metabolism, biodistribution, radiation dosimetry, and toxicology of (18)F-fluoroacetate ((18)F-FACE) in non-human primates.Mol Imaging Biol2012
23316091An investigation on stereospecific fluorination at the 2'-arabino-position of a pyrimidine nucleoside: radiosynthesis of 2'-deoxy-2'-[(18)F]fluoro-5-methyl-1-β-D-arabinofuranosyluracil.Tetrahedron2012
23133802Positron emission tomography (PET) imaging with (18)F-based radiotracers.Am J Nucl Med Mol Imaging2012
22226022Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor.Nucl Med Biol2012
20593279Synthesis and ex vivo autoradiographic evaluation of ethyl-β-D-galactopyranosyl-(1,4')-2'-deoxy-2'-[18F]fluoro-β-D-glucopyranoside--a novel radioligand for lactose-binding protein: implications for early detection of pancreatic carcinomas with PET.Mol Imaging Biol2011
21872477Fluorinated cannabinoid CB2 receptor ligands: synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives.Bioorg Med Chem2011
21912635Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model.PLoS One2011
21982570Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging.Nucl Med Biol2011
21571803Whole-body biodistribution kinetics, metabolism, and radiation dosimetry estimates of 18F-PEG6-IPQA in nonhuman primates.J Nucl Med2011
21741850Improved detection and measurement of low levels of [18F]fluoride metabolized from [18F]-labeled pyrimidine nucleoside analogues in biological samples.Nucl Med Biol2011
21364021HIF-1-dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance.Mol Cancer Res2011
21220318Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT.Proc Natl Acad Sci U S A2011
21183793Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.J Clin Invest2011
20859697Radiosynthesis and initial in vitro evaluation of [18F]F-PEG6-IPQA--a novel PET radiotracer for imaging EGFR expression-activity in lung carcinomas.Mol Imaging Biol2011
20156163Pyrimidine nucleosides in molecular PET imaging of tumor proliferation.Curr Med Chem2010
20448213Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action.Circ Res2010
20583993Radiolabeled nucleoside analogues for PET imaging of HSV1-tk gene expression.Curr Top Med Chem2010
18830258PET imaging of T cells derived from umbilical cord blood.Leukemia2009
19956730Detection of pancreatic carcinomas by imaging lactose-binding protein expression in peritumoral pancreas using [18F]fluoroethyl-deoxylactose PET/CT.PLoS One2009
19728977Repetitive noninvasive monitoring of HSV1-tk-expressing T cells intravenously infused into nonhuman primates using positron emission tomography and computed tomography with 18F-FEAU.Mol Imaging2009
19372568The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects.Mol Cancer Ther2009
19324560Radiosynthesis of F-18 labeled cytidine analog 2'-fluoro-5-iodo-l-beta-d-arabinofuranosylcytosine ([(18)F]FIAC).Appl Radiat Isot2009
19223410Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs.J Nucl Med2009
18158952In vivo measurement of cell proliferation in canine brain tumor using C-11-labeled FMAU and PET.Nucl Med Biol2008
18782048Synthesis of N3-substituted thymidine analogues for measurement of cellular kinase activity.Med Chem2008
18678355N(3)-Substituted thymidine analogues V: synthesis and preliminary PET imaging of N(3)-[(18)F]fluoroethyl thymidine and N(3)-[(18)F]fluoropropyl thymidine.Nucl Med Biol2008
18337507A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging.Proc Natl Acad Sci U S A2008
18057932Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT.Eur J Nucl Med Mol Imaging2008
17206416In vivo evaluation of 2'-deoxy-2'-[(18)F]fluoro-5-iodo-1-beta-D-arabinofuranosyluracil ([18F]FIAU) and 2'-deoxy-2'-[18F]fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil ([18F]FEAU) as markers for suicide gene expression.Eur J Nucl Med Mol Imaging2007
17383576Biodistribution and PET imaging of [(18)F]-fluoroadenosine derivatives.Nucl Med Biol2007
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Collaborators

Karmanos Cancer Institute (KCI), Wayne State University
Co-authored papers 40
Keck School of Medicine of USC
Co-authored papers 21
The Ohio State University Wexner Medical Center
Co-authored papers 17
The University of Texas MD Anderson Cancer Center
Co-authored papers 10
UT MD Anderson Cancer Center
Co-authored papers 9
Rutgers Cancer Institute of New Jersey
Co-authored papers 7
Rutgers Cancer Institute of New Jersey
Co-authored papers 7
City of Hope National Medical Center
Co-authored papers 5
Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine
Co-authored papers 3
Harvard Medical School
Co-authored papers 3
Rutgers Cancer Institute of New Jersey
Co-authored papers 3
Co-authored papers 2
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 2
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 2
PHusis Therapeutics Inc.
Co-authored papers 2
Houston Methodist Cancer Center
Co-authored papers 2
Stanford University School of Medicine
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
University of California San Diego
Co-authored papers 1
The Children's Hospital of Philadelphia
Co-authored papers 1
MD Anderson Cancer Center
Co-authored papers 1
National Cancer Institute
Co-authored papers 1
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
The Salk Institute for Biological Studies
Co-authored papers 1
MD Anderson Cancer Center
Co-authored papers 1
Texas A&M Health Science Center Institute of Biosciences and Technology
Co-authored papers 1
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 1
University of Texas MD Anderson Cancer Center
Co-authored papers 1
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1