Author details

Full Name

Richard H Myers

Affiliation

ORCID

Career Start Year

1977

Papers

268

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33938021	Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease.	Ann Neurol	2021
34166773	Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington's disease.	Prog Neurobiol	2021
32733076	A glycomics and proteomics study of aging and Parkinson's disease in human brain.	Scientific Reports	2020
32087949	Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington's Disease.	Biol Psychiatry	2020
31619230	The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington's disease brain.	BMC Medical Genomics	2019
29321258	Functional variants in the <i>LRRK2</i> gene confer shared effects on risk for Crohn's disease and Parkinson's disease.	Sci Transl Med	2018
30061609	Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.	Nat Commun	2018
29375298	Evidence for a Pan-Neurodegenerative Disease Response in Huntington's and Parkinson's Disease Expression Profiles.	Front Mol Neurosci	2018
29282329	MicroRNAs in CSF as prodromal biomarkers for Huntington disease in the PREDICT-HD study.	Neurology	2018
28166718	Evaluation of logistic regression models and effect of covariates for case-control study in RNA-Seq analysis.	BMC Bioinformatics	2017
28465506	The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.	Scientific Reports	2017
28934397	A modifier of Huntington's disease onset at the MLH1 locus.	Human Molecular Genetics	2017
28832564	Haplotype-based stratification of Huntington's disease.	European Journal of Human Genetics	2017
27716130	Novel microRNA discovery using small RNA sequencing in post-mortem human brain.	BMC Genomics	2016
26973511	microRNA Profiles in Parkinson's Disease Prefrontal Cortex.	Frontiers in Aging Neuroscience	2016
27096366	Parkinson-associated risk variant in distal enhancer of Î±-synuclein modulates target gene expression.	Nature	2016
26793951	Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease.	BMC Medical Genomics	2016
26833098	Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.	Nat Commun	2016
27476799	Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.	J Bone Miner Res	2016
27454300	Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.	PLoS One	2016
26569098	Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials.	JAMA Neurol	2016
27692902	DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study.	Lancet Neurol	2016
27508417	The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane.	PLoS One	2016
26573701	Study of plasma-derived miRNAs mimic differences in Huntington's disease brain.	Movement Disorders	2015
25480889	Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.	Hum Mol Genet	2015
25889241	miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement.	BMC Med Genomics	2015
26444025	The Genetic Modifiers of Motor OnsetAgeÂ (GeM MOA) Website: Genome-wide Association Analysis for Genetic Modifiers of Huntington's Disease.	Journal of Huntington's disease	2015
26320893	Sequence-Level Analysis of the Major European Huntington Disease Haplotype.	Am J Hum Genet	2015
26131930	Directional dominance on stature and cognition inÂ diverse human populations.	Nature	2015
26636579	RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression.	PLoS One	2015
26636336	The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease.	PLoS One	2015
26496077	Evidence of Extensive Alternative Splicing in Post Mortem Human Brain HTT Transcription by mRNA Sequencing.	PLoS ONE	2015
25064009	Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.	Nat Genet	2014
25467983	Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition.	Neuron	2014
23838599	Correction for multiple testing in a gene region.	European Journal of Human Genetics	2014
24586208	MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.	PLoS Genet	2014
24510495	Feasibility of Huntington disease trials in the disease prodrome.	Neurology	2014
23644918	Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset.	Neurogenetics	2013
23750121	Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study.	PLoS Med	2013
23071545	Evaluation of Parkinson disease risk variants as expression-QTLs.	PLoS ONE	2012
22438815	Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.	PLoS Genet	2012
22387017	Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region.	Am J Hum Genet	2012
22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Am J Respir Crit Care Med	2012
22530163	Postmortem Interval Influences Î±-Synuclein Expression in Parkinson Disease Brain.	Parkinson's Disease	2012
22279548	Genetic signatures of exceptional longevity in humans.	PLoS One	2012
22825315	Population stratification may bias analysis of PGC-1Î± as a modifier of age at Huntington disease motor onset.	Hum Genet	2012
22771793	TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease.	Biochem Biophys Res Commun	2012
22323755	CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.	Neurology	2012
22451204	Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.	Ann Neurol	2012
22761592	Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.	PLoS Genet	2012