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Author Details
Full Name
Lenore Pereira
Affiliation
University of California san francisco
ORCID
Career Start Year
1976
Papers
118
H Index
55
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35891239
Neutralizing Antibodies to Human Cytomegalovirus Recombinant Proteins Reduce Infection in an Ex Vivo Model of Developing Human Placentas.
Vaccines (Basel)
2022
31250000
Zika Virus Nonstructural Protein 1 Disrupts Glycosaminoglycans and Causes Permeability in Developing Human Placentas.
J Infect Dis
2020
31065796
Survey of cellular immune responses to human cytomegalovirus infection in the microenvironment of the uterine-placental interface.
Med Microbiol Immunol
2019
31569508
Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas.
Vaccines (Basel)
2019
29106643
Zika Virus Replicates in Proliferating Cells in Explants From First-Trimester Human Placentas, Potential Sites for Dissemination of Infection.
J Infect Dis
2018
30048217
Congenital Viral Infection: Traversing the Uterine-Placental Interface.
Annu Rev Virol
2018
29172071
Zika virus infection of first-trimester human placentas: utility of an explant model of replication to evaluate correlates of immune protection ex vivo.
Curr Opin Virol
2017
28433705
Maternal immunisation: collaborating with mother nature.
Lancet Infect Dis
2017
28477968
Congenital cytomegalovirus infection undermines early development and functions of the human placenta.
Placenta
2017
27443522
Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission.
Cell Host Microbe
2016
27638253
Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta.
Am J Pathol
2016
25534746
A high-affinity native human antibody neutralizes human cytomegalovirus infection of diverse cell types.
Antimicrob Agents Chemother
2015
25741001
Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta.
J Virol
2015
24403553
Intrauterine growth restriction caused by underlying congenital cytomegalovirus infection.
J Infect Dis
2014
24651029
HCMV infection of human trophoblast progenitor cells of the placenta is neutralized by a human monoclonal antibody to glycoprotein B and not by antibodies to the pentamer complex.
Viruses
2014
24334684
Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity.
Clin Vaccine Immunol
2014
24492306
Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets.
MAbs
2014
24257421
Cytomegalovirus infection and antibody protection of the developing placenta.
Clin Infect Dis
2013
22959908
Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model.
Am J Pathol
2012
21592978
Have we overlooked congenital cytomegalovirus infection as a cause of stillbirth?
J Infect Dis
2011
20227052
Screening for cytomegalovirus during pregnancy.
Am J Obstet Gynecol
2010
20651234
Antibody treatment promotes compensation for human cytomegalovirus-induced pathogenesis and a hypoxia-like condition in placentas with congenital infection.
Am J Pathol
2010
19854676
Cytomegalovirus-specific, high-avidity IgG with neutralizing activity in maternal circulation enriched in the fetal bloodstream.
J Clin Virol
2009
18349127
Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.
Am J Pathol
2008
18637517
Cytomegalovirus infection in the human placenta: maternal immunity and developmentally regulated receptors on trophoblasts converge.
Curr Top Microbiol Immunol
2008
16822542
Cytotrophoblasts infected with a pathogenic human cytomegalovirus strain dysregulate cell-matrix and cell-cell adhesion molecules: a quantitative analysis.
Placenta
2007
17314173
Developmental regulation of human cytomegalovirus receptors in cytotrophoblasts correlates with distinct replication sites in the placenta.
J Virol
2007
17317422
Recent advances in the prevention and treatment of congenital cytomegalovirus infections.
Semin Perinatol
2007
17170095
Gene expression profiling of the human maternal-fetal interface reveals dramatic changes between midgestation and term.
Endocrinology
2007
16386950
Patterns of human cytomegalovirus infection in term placentas: a preliminary analysis.
J Clin Virol
2006
16565496
Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis.
Am J Pathol
2006
15817386
Insights into viral transmission at the uterine-placental interface.
Trends Microbiol
2005
14990702
Human cytomegalovirus interleukin-10 downregulates metalloproteinase activity and impairs endothelial cell migration and placental cytotrophoblast invasiveness in vitro.
J Virol
2004
15272412
Viral and bacterial pathogens at the maternal-fetal interface.
J Infect Dis
2004
14645586
Human cytomegalovirus transmission from the uterus to the placenta correlates with the presence of pathogenic bacteria and maternal immunity.
J Virol
2003
12490403
Transmission of human cytomegalovirus from infected uterine microvascular endothelial cells to differentiating/invasive placental cytotrophoblasts.
Virology
2002
10888620
Human cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis.
J Virol
2000
10482621
An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B is a signal for endocytosis from the plasma membrane.
J Virol
1999
9696834
Human cytomegalovirus glycoprotein B contains autonomous determinants for vectorial targeting to apical membranes of polarized epithelial cells.
J Virol
1998
9621030
A novel human cytomegalovirus glycoprotein, gpUS9, which promotes cell-to-cell spread in polarized epithelial cells, colocalizes with the cytoskeletal proteins E-cadherin and F-actin.
J Virol
1998
9188570
The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection.
J Virol
1997
9260696
Humoral immune response to functional regions of human cytomegalovirus glycoprotein B.
J Med Virol
1997
8558129
Role of apical and basolateral membranes in replication of human cytomegalovirus in polarized retinal pigment epithelial cells.
J Gen Virol
1996
8970961
Accessory human cytomegalovirus glycoprotein US9 in the unique short component of the viral genome promotes cell-to-cell transmission of virus in polarized epithelial cells.
J Virol
1996
8892927
Mutations in the carboxyl-terminal hydrophobic sequence of human cytomegalovirus glycoprotein B alter transport and protein chaperone binding.
J Virol
1996
7748487
Conformation-defective herpes simplex virus 1 glycoprotein B activates the promoter of the grp94 gene that codes for the 94-kD stress protein in the endoplasmic reticulum.
DNA Cell Biol
1995
8668948
Deletion mutants in human cytomegalovirus glycoprotein US9 are impaired in cell-cell transmission and in altering tight junctions of polarized human retinal pigment epithelial cells.
Scand J Infect Dis Suppl
1995
7778290
Mutated forms of human cytomegalovirus glycoprotein B are impaired in inducing syncytium formation.
Virology
1995
7952927
Function of glycoprotein B homologues of the family herpesviridae.
Infect Agents Dis
1994
8184537
Function of human cytomegalovirus glycoprotein B: syncytium formation in cells constitutively expressing gB is blocked by virus-neutralizing antibodies.
Virology
1994
1 - 50 of 118
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Co-authored papers
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Mallur S Madhusudhan
Indian Institute of Science Education and Research Pune
Co-authored papers
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Vanderbilt University Medical Center
Co-authored papers
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Kui-Tzu Feng
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Jean Yee Hwa Yang
The University of Sydney
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Andrej Sali (CM4AI)
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Virginia D Winn
Stanford University
Co-authored papers
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Natalie C J Strynadka
The University of British Columbia
Co-authored papers
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Andrew D Yurochko
Louisiana State University
Co-authored papers
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Zhiqiang An
Zhengzhou University
Co-authored papers
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Agnes C Paquet
Universite Cote d'Azur, CNRS UMR5
Co-authored papers
1
Tobias R Kollmann
Telethon Kids Institute
Co-authored papers
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Nesli Basgoz
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David A Bernlohr
University of Minnesota-Twin Cities
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Hadassah Hebrew University Medical Center
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