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Author Details

Sergei Zolotukhin
College of Medicine, University of Florida
1994
107
48
PMIDPaper TitleJournal TitlePublished Year
36950804Characterization of a Bioengineered AAV3B Capsid Variant with Enhanced Hepatocyte Tropism and Immune Evasion.Hum Gene Ther2023
37896760Exploring the Comprehensive Kozak Sequence Landscape for AAV Production in Sf9 System.Viruses2023
35093287AAV capsid design: A Goldilocks challenge.Trends Mol Med2022
36018583Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution.Transl Vis Sci Technol2022
34298128A comprehensive study of a 29-capsid AAV library in a non-human primate central nervous system.Mol Ther2021
33830080The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma.JCI Insight2021
33927269Mixture interactions at mammalian olfactory receptors are dependent on the cellular environment.Sci Rep2021
34699781Scratching the surface of RGD-directed AAV capsid engineering.Mol Ther2021
33145371Engineering and <i>In Vitro</i> Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity.Mol Ther Methods Clin Dev2020
33511242Applying machine learning to predict viral assembly for adeno-associated virus capsid libraries.Mol Ther Methods Clin Dev2020
30886878Achieving High-Yield Production of Functional AAV5 Gene Delivery Vectors via Fedbatch in an Insect Cell-One Baculovirus System.Mol Ther Methods Clin Dev2019
31649960Removal of Endotoxin from rAAV Samples Using a Simple Detergent-Based Protocol.Mol Ther Methods Clin Dev2019
31125082Taste Receptor Cells in Mice Express Receptors for the Hormone Adiponectin.Chem Senses2019
30073177Helper-free Production of Laboratory Grade AAV and Purification by Iodixanol Density Gradient Centrifugation.Mol Ther Methods Clin Dev2018
27823858Ambient temperature modulates the effects of the Prader-Willi syndrome candidate gene Snord116 on energy homeostasis.Neuropeptides2017
28460646Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models.J Transl Med2017
28480313An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8<sup>+</sup> T Cells.Mol Ther Methods Clin Dev2017
28125901OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2, and AAV8 Vectors with Minimal Encapsidation of Foreign DNA.Hum Gene Ther Methods2017
28094877Hypothalamus Specific Re-Introduction of SNORD116 into Otherwise Snord116 Deficient Mice Increased Energy Expenditure.J Neuroendocrinol2017
28890324Direct Head-to-Head Evaluation of Recombinant Adeno-associated Viral Vectors Manufactured in Human versus Insect Cells.Mol Ther2017
26726071Snord116 is critical in the regulation of food intake and body weight.Sci Rep2016
26611585Altering Tropism of rAAV by Directed Evolution.Methods Mol Biol2016
27233218Up-regulation of activating transcription factor 4 induces severe loss of dopamine nigral neurons in a rat model of Parkinson's disease.Neurosci Lett2016
27144303Limited ATF4 Expression in Degenerating Retinas with Ongoing ER Stress Promotes Photoreceptor Survival in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa.PLoS One2016
26824232Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.PLoS One2016
25863526The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons.Neurobiol Aging2015
26388463E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV Evolution.Mol Ther2015
26793739High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing.Mol Ther Methods Clin Dev2015
26690810Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?Hum Gene Ther2015
26134901OneBac 2.0: Sf9 Cell Lines for Production of AAV5 Vectors with Enhanced Infectivity and Minimal Encapsidation of Foreign DNA.Hum Gene Ther2015
24299301OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy.Hum Gene Ther2014
26015974A simplified purification protocol for recombinant adeno-associated virus vectors.Mol Ther Methods Clin Dev2014
25522272An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina.Cell Death Dis2014
25218388Identification of low-expressing transcripts of the NPY receptors' family in the murine lingual epithelia.Methods Mol Biol2014
25048217Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants.Mol Ther2014
24535841Neuropeptide y attenuates stress-induced bone loss through suppression of noradrenaline circuits.J Bone Miner Res2014
22994880Metabolic hormones in saliva: origins and functions.Oral Dis2013
24043261Modulation of taste responsiveness by the satiation hormone peptide YY.FASEB J2013
24259562Salivary peptide tyrosine-tyrosine 3-36 modulates ingestive behavior without inducing taste aversion.J Neurosci2013
23926356Structural insights into adeno-associated virus serotype 5.J Virol2013
23760240Capsid antibodies to different adeno-associated virus serotypes bind common regions.J Virol2013
21915102Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models.Mol Ther2012
23264889Development of Novel Recombinant AAV Vectors and Strategies for the Potential Gene Therapy of Hemophilia.J Genet Syndr Gene Ther2012
23050020Distribution of Y-receptors in murine lingual epithelia.PLoS One2012
22768253Y1 and Y5 receptors are both required for the regulation of food intake and energy homeostasis in mice.PLoS One2012
22497875High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.Vaccine2012
22496238Structural insight into the unique properties of adeno-associated virus serotype 9.J Virol2012
22034025Design and construction of functional AAV vectors.Methods Mol Biol2011
22028819Salivary PYY: a putative bypass to satiety.PLoS One2011
20736929High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.Mol Ther2010
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Collaborators

College of Medicine, University of Florida
Co-authored papers 38
University of Florida
Co-authored papers 11
Garvan Institute of Medical Research
Co-authored papers 10
College of Medicine, University of Florida
Co-authored papers 8
Co-authored papers 8
American College of Medical Informatics, Department of Veteran Affairs, Harvard University T H Chan School of Public Health, Massachusetts Institute of Technology, The American Society for Clinical Investigation, University of Kentucky, Vanderbilt University Medical Center, Vanderbilt University Medical School
Co-authored papers 7
Co-authored papers 6
Malcom Randall Veterans Affairs Medical Center
Co-authored papers 6
University of Florida
Co-authored papers 5
Education and Clinical Center, Department of Veterans Affairs Medical Center
Co-authored papers 4
Co-authored papers 3
and Clinical Center, Department of Veterans Affairs Medical Center
Co-authored papers 3
University of Florida
Co-authored papers 2
University of Florida
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Louisiana State University Health Sciences Center
Co-authored papers 2
University of Florida College of Medicine.
Co-authored papers 2
Co-authored papers 2
University of California san francisco
Co-authored papers 1
University of Alabama at Birmingham
Co-authored papers 1
Co-authored papers 1
University of Florida College of Medicine
Co-authored papers 1
College of Medicine, University of Florida
Co-authored papers 1
Co-authored papers 1
University of Michigan School of Medicine ann arbor
Co-authored papers 1
University of Florida College of Medicine
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1