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Author Details

Benjamin S Braun
Benioff Children's Hospitals, University of California san francisco
1992
44
29
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36700399Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia.Haematologica2023
37036306Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies.Pediatr Blood Cancer2023
34464969Nf1 and Sh2b3 mutations cooperate in vivo in a mouse model of juvenile myelomonocytic leukemia.Blood Adv2021
33626861The <i>EBF1-PDGFRB</i> T681I mutation is highly resistant to imatinib and dasatinib <i>in vitro</i> and detectable in clinical samples prior to treatment.Haematologica2021
31511612Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing.Leukemia2020
32990679KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.JCI Insight2020
30862722Bcl-2 Is a Therapeutic Target for Hypodiploid B-Lineage Acute Lymphoblastic Leukemia.Cancer Res2019
31738828Paroxysmal cold hemoglobinuria successfully treated with complement inhibition.Blood Adv2019
30952657Tissue-Specific Oncogenic Activity of KRAS<sup>A146T</sup>.Cancer Discov2019
29259179Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.Nat Commun2017
28993414A Collaborative Model for Accelerating the Discovery and Translation of Cancer Therapies.Cancer Res2017
26727232Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.J Clin Invest2016
26965285Targeting the PI3K/Akt pathway in murine MDS/MPN driven by hyperactive Ras.Leukemia2016
25395418Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.Blood2015
26260086Traxtile: Interactive editing of cell tracks in time-lapse images.Biotechniques2015
23221337Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.J Clin Invest2013
24300897PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras.Sci Signal2013
22898602Targeting oncogenic Ras signaling in hematologic malignancies.Blood2012
23019203KIT's ship comes in.Blood2012
21163920Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.Blood2011
21398220Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.Blood2011
21451123A MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice.Sci Transl Med2011
20194733Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.Proc Natl Acad Sci U S A2010
20694012Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia.Nat Genet2010
19296721Oncogenic Kras initiates leukemia in hematopoietic stem cells.PLoS Biol2009
19647218The SPS affair: a complex tale of illicit proliferation.Cancer Cell2009
19345332JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.Cancer Cell2009
19186049Pediatric malignancies: update on sarcomas and leukemia development in children.Curr Opin Genet Dev2009
18413813Targeting Ras in myeloid leukemias.Clin Cancer Res2008
17192389K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells.Blood2007
16261595Inherited predispositions and hyperactive Ras in myeloid leukemogenesis.Pediatr Blood Cancer2006
16720837Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo.Blood2006
16427986Congenital leukemia cutis with subsequent development of leukemia.J Am Acad Dermatol2006
15050910The sum is greater than the FGFR1 partner.Cancer Cell2004
14699048Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.Proc Natl Acad Sci U S A2004
14982883Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.Blood2004
9398859EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic.Nat Genet1997
9000139EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene.Oncogene1996
7700648A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.Oncogene1995
7845667Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene.Oncogene1995
7623854Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis.Mol Cell Biol1995
7680609Prevention of experimental autoimmune arthritis with a peptide fragment of type II collagen.Eur J Immunol1993
8246959The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.Mol Cell Biol1993
1476795Creation of a yeast artificial chromosome fragmentation vector based on lysine-2.Genet Anal Tech Appl1992
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Collaborators

Mignon L Loh
University of Washington
Co-authored papers 10
Jon Akutagawa
Benioff Children's Hospital, University of California san francisco
Co-authored papers 9
Stephen L Lessnick
The Ohio State University College of Medicine
Co-authored papers 4
Tyler Jacks
Co-authored papers 3
Neil P Shah
University of California San Francisco
Co-authored papers 2
Adam B Olshen
12224University of California san francisco
Co-authored papers 2
Kevan M Shokat
University of California San Francisco
Co-authored papers 2
Keiko Akagi
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Charles G Mullighan
St Jude Children's Research Hospital
Co-authored papers 2
Garry P Nolan
Stanford University School of Medicine
Co-authored papers 1
Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 1
Thai Hoa Tran
Universite de Montreal
Co-authored papers 1
Martin Zenker
Co-authored papers 1
Jonathan V Nguyen
Moffitt Cancer Center
Co-authored papers 1
Yunfeng Dai
Colleges of Medicine, University of Florida
Co-authored papers 1
John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Kenneth D Westover
University of Texas Southwestern Medical Center
Co-authored papers 1
Martine F Roussel
St. Jude Children's Research Hospital
Co-authored papers 1
E Alejandro Sweet-Cordero
University of California San Francisco
Co-authored papers 1
Joseph F Costello
University of California san francisco
Co-authored papers 1
Meenakshi Devidas
St Jude Children's Research Hospital
Co-authored papers 1
Thomas De Raedt
Co-authored papers 1
Catherine C Smith
University of California San Francisco
Co-authored papers 1
Charlotte M Niemeyer
Co-authored papers 1
Anthony V Moorman
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 1
Kathryn G Roberts
St Jude Children's Research Hospital
Co-authored papers 1
Ritu Roy
University of California San Francisco.
Co-authored papers 1
Steven P Gygi
Harvard Medical School
Co-authored papers 1
Amaro Taylor-Weiner
Co-authored papers 1
Kara L Davis
Stanford University School of Medicine
Co-authored papers 1
Release 1.2