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Author Details

Qun Pan
University of Toronto
2000
48
37
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32069328An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing.PLoS Pathog2020
28157508Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors.Mol Cell2017
27251103Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine.Sci Rep2016
27365209The RNA-binding profile of Acinus, a peripheral component of the exon junction complex, reveals its role in splicing regulation.RNA2016
27561422The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress.BMC Genomics2016
25877919Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.Genes Dev2015
26135620A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition.Sci Rep2015
26116661Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.Development2015
26109054Corrigendum: Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming.Genes Dev2015
25031339Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer.J Virol2014
25258385Widespread intron retention in mammals functionally tunes transcriptomes.Genome Res2014
23246434Latent regulatory potential of human-specific repetitive elements.Mol Cell2013
22454538Alternative splicing networks regulated by signaling in human T cells.RNA2012
23258890The evolutionary landscape of alternative splicing in vertebrate species.Science2012
22749401Tissue-specific alternative splicing remodels protein-protein interaction networks.Mol Cell2012
21177968Genome-wide analysis of alternative splicing in Caenorhabditis elegans.Genome Res2011
21884984Cross-regulation between an alternative splicing activator and a transcription repressor controls neurogenesis.Mol Cell2011
21924763An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.Cell2011
21325135Regulation of alternative splicing by the core spliceosomal machinery.Genes Dev2011
21163941Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation.Genome Res2011
19906824microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells.Mol Hum Reprod2010
20797886The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation.Mol Cell2010
20445623Deciphering the splicing code.Nature2010
20566848Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.Proc Natl Acad Sci U S A2010
20133523Regulation of alternative splicing by histone modifications.Science2010
19737518Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein.Cell2009
18182067Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids.J Cell Mol Med2008
19088369The expression and ovarian steroid regulation of endometrial micro-RNAs.Reprod Sci2008
18951330MicroRNA signature and regulatory functions in the endometrium during normal and disease states.Semin Reprod Med2008
18978789Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing.Nat Genet2008
18443041Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay.Mol Cell Biol2008
17095519Endometrial expression of epithelial neutrophil-activating peptide-78 during the menstrual cycle or in progestin-only contraceptive users with breakthrough bleeding and the influence of doxycycline therapy.Hum Reprod2007
17978102Global analysis of alternative splicing differences between humans and chimpanzees.Genes Dev2007
17565696Functional coordination of alternative splicing in the mammalian central nervous system.Genome Biol2007
17766684The expression profile of micro-RNA in endometrium and endometriosis and the influence of ovarian steroids on their expression.Mol Hum Reprod2007
17718906Genomic and proteomic profiling II: comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars.Reprod Biol Endocrinol2007
17716379Genomic and proteomic profiling I: leiomyomas in African Americans and Caucasians.Reprod Biol Endocrinol2007
17307815Global analysis of alternative splicing during T-cell activation.RNA2007
16418482Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression.Genes Dev2006
16737462Effects of acute ethanol exposure on regulatory mechanisms of Bcl-2-associated apoptosis promoter, bad, in neonatal rat cerebellum: differential effects during vulnerable and resistant developmental periods.Alcohol Clin Exp Res2006
16891626Doxycycline alters the expression of inflammatory and immune-related cytokines and chemokines in human endometrial cells: implication in irregular uterine bleeding.Hum Reprod2006
15661351Alternative splicing of conserved exons is frequently species-specific in human and mouse.Trends Genet2005
16127451Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs.Nat Genet2005
16035105Functional mechanisms of apoptosis-related proteins in neonatal rat cerebellum are differentially influenced by ethanol at postnatal days 4 and 7.J Neurosci Res2005
16024002Mitochondrially targeted vitamin E and vitamin E mitigate ethanol-mediated effects on cerebellar granule cell antioxidant defense systems.Brain Res2005
15588312The functional landscape of mouse gene expression.J Biol2004
15610736Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform.Mol Cell2004
10946278Two clusters of acidic amino acids near the NH2 terminus of complement component C4 alpha'-chain are important for C2 binding.J Immunol2000
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Collaborators

Benjamin J Blencowe
University of Toronto
Co-authored papers 35
Brendan J Frey
University of Toronto
Co-authored papers 10
Timothy R Hughes
University of Toronto
Co-authored papers 7
Ofer Shai
University of Toronto
Co-authored papers 6
John A Calarco
University of Toronto
Co-authored papers 5
Wen Zhang
Nanjing Agricultural University
Co-authored papers 5
Quaid Morris
Sloan Kettering Institute
Co-authored papers 5
Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 5
Naveed Mohammad
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 4
Hong Han
Hangzhou City University
Co-authored papers 3
Duncan T Odom
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 3
Alessandro Datti
University of Perugia
Co-authored papers 3
Frederick S Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 3
Derek van der Kooy
University of Toronto
Co-authored papers 3
Eric Sat
The University of Hong Kong
Co-authored papers 2
Ulrich Braunschweig
University of Toronto
Co-authored papers 2
Jane E Aubin
University of Toronto
Co-authored papers 2
Michael D Wilson
SickKids Research Institute
Co-authored papers 2
Janet Rossant
The Hospital for Sick Children
Co-authored papers 2
Mark D Robinson
University of Zurich
Co-authored papers 2
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 2
Benoit G Bruneau
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
Co-authored papers 2
David F Archer
Co-authored papers 2
Tomas Babak
Queen's University
Co-authored papers 2
Richard Chang
University of Toronto, 1 King's College Circle
Co-authored papers 2
Zeynep Coban Akdemir
Baylor College of Medicine
Co-authored papers 2
Stephen Watt
Wellcome Sanger Institute
Co-authored papers 2
Malina A Bakowski
a division of The Scripps Research Institute La Jolla
Co-authored papers 2
Debashish Ray
Co-authored papers 2
Jason Moffat
University of Toronto
Co-authored papers 1
Release 1.2