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Author Details
Full Name
Carolina S Ilkow
Affiliation
Ottawa Hospital Research Institute
ORCID
Career Start Year
2006
Papers
51
H Index
16
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36603053
Identifying barriers and enablers to rigorous conduct and reporting of preclinical laboratory studies.
PLoS Biol
2023
37735876
Optimal delivery of RNA interference by viral vectors for cancer therapy.
Mol Ther
2023
37822719
A TÂ cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.
Mol Ther Methods Clin Dev
2023
37153626
Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus.
Front Immunol
2023
37242495
Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.
Pharmaceuticals (Basel)
2023
37236967
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.
Nat Commun
2023
37100284
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.
J Biol Chem
2023
36969187
Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy <i>via</i> lipid modulation of the tumor microenvironment.
Front Immunol
2023
36587124
Generation and Quantification of Cytotoxic Lymphocytes Following Oncolytic Virus Infection of Multi-cellular Tumor Spheroids.
Methods Mol Biol
2023
36713447
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.
Front Immunol
2023
36674550
Extracellular Vesicles and Viruses: Two Intertwined Entities.
Int J Mol Sci
2023
34687845
Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and TÂ cell immune response against SARS-CoV-2 infection.
Mol Ther
2022
35393414
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.
Nat Commun
2022
35526097
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.
Mol Ther
2022
36405739
Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.
Front Immunol
2022
35229029
Intravesical immunotherapy with a GM-CSF armed oncolytic vesicular stomatitis virus improves outcome in bladder cancer.
Mol Ther Oncolytics
2022
34359574
Oncolytic Virus Immunotherapy.
Cancers (Basel)
2021
37579261
Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic.
ACS Nanosci Au
2021
33706157
SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.
Biosens Bioelectron
2021
33668756
Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.
Int J Mol Sci
2021
33809836
A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion.
Nanomaterials (Basel)
2021
33555379
Personalized oncology and BRAF<sup>K601N</sup> melanoma: model development, drug discovery, and clinical correlation.
J Cancer Res Clin Oncol
2021
33578036
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2Â S for viral entry.
Mol Ther
2021
34459810
Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter.
J Vis Exp
2021
34152313
Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection.
J Vis Exp
2021
31486045
Generating Primary Models of Human Cancer to Aid in the Development of Clinically Relevant Oncolytic Viruses.
Methods Mol Biol
2020
32958389
Redirecting oncolytic viruses: Engineering opportunists to take control of the tumour microenvironment.
Cytokine Growth Factor Rev
2020
32872641
Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.
Membranes (Basel)
2020
32722184
Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis.
Cancers (Basel)
2020
31276026
Assessing the Completeness of Reporting in Preclinical Oncolytic Virus Therapy Studies.
Mol Ther Oncolytics
2019
29367345
Dimethyl fumarate potentiates oncolytic virotherapy through NF-κB inhibition.
Sci Transl Med
2018
29921327
Enhanced susceptibility of cancer cells to oncolytic rhabdo-virotherapy by expression of Nodamura virus protein B2 as a suppressor of RNA interference.
J Immunother Cancer
2018
29724655
Lighting a Fire in the Tumor Microenvironment Using Oncolytic Immunotherapy.
EBioMedicine
2018
28810141
A Viro-Immunotherapy Triple Play for the Treatment of Glioblastoma.
Cancer Cell
2017
27909702
Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies.
Mol Ther Oncolytics
2016
25817275
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing.
Nat Commun
2015
26212250
VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection.
Cancer Cell
2015
25894825
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Nat Med
2015
25807289
Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques.
Mol Ther
2015
24453963
From scourge to cure: tumour-selective viral pathogenesis as a new strategy against cancer.
PLoS Pathog
2014
24695102
Maraba MG1 virus enhances natural killer cell function via conventional dendritic cells to reduce postoperative metastatic disease.
Mol Ther
2014
24463573
Smac mimetics and innate immune stimuli synergize to promote tumor death.
Nat Biotechnol
2014
24456140
Phosphorylation and membrane association of the Rubella virus capsid protein is important for its anti-apoptotic function.
Cell Microbiol
2014
23393196
Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans.
Cancer Res
2013
22186794
The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers.
Mol Ther
2012
21379337
The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax.
PLoS Pathog
2011
19846524
The rubella virus capsid protein inhibits mitochondrial import.
J Virol
2010
20353299
Rubella virus capsid protein: a small protein with big functions.
Future Microbiol
2010
18305028
Rubella virus capsid protein interacts with poly(a)-binding protein and inhibits translation.
J Virol
2008
18258415
Modulation of signaling pathways by RNA virus capsid proteins.
Cell Signal
2008
1 - 50 of 51
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row(s) 1 - 30 of 30
Collaborators
John C Bell
Ottawa Hospital Research Institute
Co-authored papers
32
Jean-Simon Diallo
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers
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Taha Azad
Ottawa Hospital Research Institute
Co-authored papers
19
Mathieu J F Crupi
Cancer Research Institute, Queen's University
Co-authored papers
18
Ragunath Singaravelu
Ottawa Hospital Research Institute
Co-authored papers
14
Joanna Poutou
Ottawa Hospital Research Institute
Co-authored papers
12
Zaid Taha
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers
12
Abera Surendran
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers
11
Julia Petryk
Ottawa Hospital Research Institute
Co-authored papers
11
Rebecca C Auer
The Ottawa Hospital Research Institute
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9
Adrian Pelin
University of Ottawa
Co-authored papers
8
Xiao-Peng He
Ottawa Hospital Research Institute
Co-authored papers
8
Christiano Tanese de Souza
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers
7
Brian A Keller
The Ottawa Hospital/University of Ottawa
Co-authored papers
6
Marie-??ve Wedge
Ottawa Hospital Research Institute
Co-authored papers
4
Larissa A Pikor
Ottawa Hospital Research Institute
Co-authored papers
4
Victoria A Jennings
Leeds Institute of Medical Research at St James's, University of Leeds
Co-authored papers
4
Sarwat T Khan
Ottawa Hospital Research Institute
Co-authored papers
3
Almohanad A Alkayyal
College of Applied Medical Sciences, University of Tabuk
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Alan Melcher
The Institute of Cancer Research
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Meaghan Boileau
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Avijit Chatterjee
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