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Author Details

Carolina S Ilkow
Ottawa Hospital Research Institute
2006
51
16
PMIDPaper TitleJournal TitlePublished Year
36603053Identifying barriers and enablers to rigorous conduct and reporting of preclinical laboratory studies.PLoS Biol2023
37735876Optimal delivery of RNA interference by viral vectors for cancer therapy.Mol Ther2023
37822719A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infection.Mol Ther Methods Clin Dev2023
37153626Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus.Front Immunol2023
37242495Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy.Pharmaceuticals (Basel)2023
37236967Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.Nat Commun2023
37100284Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.J Biol Chem2023
36969187Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy <i>via</i> lipid modulation of the tumor microenvironment.Front Immunol2023
36587124Generation and Quantification of Cytotoxic Lymphocytes Following Oncolytic Virus Infection of Multi-cellular Tumor Spheroids.Methods Mol Biol2023
36713447CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX.Front Immunol2023
36674550Extracellular Vesicles and Viruses: Two Intertwined Entities.Int J Mol Sci2023
34687845Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection.Mol Ther2022
35393414Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.Nat Commun2022
35526097Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.Mol Ther2022
36405739Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer.Front Immunol2022
35229029Intravesical immunotherapy with a GM-CSF armed oncolytic vesicular stomatitis virus improves outcome in bladder cancer.Mol Ther Oncolytics2022
34359574Oncolytic Virus Immunotherapy.Cancers (Basel)2021
37579261Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic.ACS Nanosci Au2021
33706157SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.Biosens Bioelectron2021
33668756Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.Int J Mol Sci2021
33809836A High-Throughput NanoBiT-Based Serological Assay Detects SARS-CoV-2 Seroconversion.Nanomaterials (Basel)2021
33555379Personalized oncology and BRAF<sup>K601N</sup> melanoma: model development, drug discovery, and clinical correlation.J Cancer Res Clin Oncol2021
33578036Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.Mol Ther2021
34459810Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter.J Vis Exp2021
34152313Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection.J Vis Exp2021
31486045Generating Primary Models of Human Cancer to Aid in the Development of Clinically Relevant Oncolytic Viruses.Methods Mol Biol2020
32958389Redirecting oncolytic viruses: Engineering opportunists to take control of the tumour microenvironment.Cytokine Growth Factor Rev2020
32872641Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.Membranes (Basel)2020
32722184Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis.Cancers (Basel)2020
31276026Assessing the Completeness of Reporting in Preclinical Oncolytic Virus Therapy Studies.Mol Ther Oncolytics2019
29367345Dimethyl fumarate potentiates oncolytic virotherapy through NF-κB inhibition.Sci Transl Med2018
29921327Enhanced susceptibility of cancer cells to oncolytic rhabdo-virotherapy by expression of Nodamura virus protein B2 as a suppressor of RNA interference.J Immunother Cancer2018
29724655Lighting a Fire in the Tumor Microenvironment Using Oncolytic Immunotherapy.EBioMedicine2018
28810141A Viro-Immunotherapy Triple Play for the Treatment of Glioblastoma.Cancer Cell2017
27909702Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies.Mol Ther Oncolytics2016
25817275Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing.Nat Commun2015
26212250VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection.Cancer Cell2015
25894825Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.Nat Med2015
25807289Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques.Mol Ther2015
24453963From scourge to cure: tumour-selective viral pathogenesis as a new strategy against cancer.PLoS Pathog2014
24695102Maraba MG1 virus enhances natural killer cell function via conventional dendritic cells to reduce postoperative metastatic disease.Mol Ther2014
24463573Smac mimetics and innate immune stimuli synergize to promote tumor death.Nat Biotechnol2014
24456140Phosphorylation and membrane association of the Rubella virus capsid protein is important for its anti-apoptotic function.Cell Microbiol2014
23393196Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans.Cancer Res2013
22186794The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers.Mol Ther2012
21379337The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax.PLoS Pathog2011
19846524The rubella virus capsid protein inhibits mitochondrial import.J Virol2010
20353299Rubella virus capsid protein: a small protein with big functions.Future Microbiol2010
18305028Rubella virus capsid protein interacts with poly(a)-binding protein and inhibits translation.J Virol2008
18258415Modulation of signaling pathways by RNA virus capsid proteins.Cell Signal2008
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Collaborators

Ottawa Hospital Research Institute
Co-authored papers 32
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers 21
Ottawa Hospital Research Institute
Co-authored papers 19
Cancer Research Institute, Queen's University
Co-authored papers 18
Ottawa Hospital Research Institute
Co-authored papers 14
Ottawa Hospital Research Institute
Co-authored papers 12
Ottawa Hospital Research Institute, University of Ottawa
Co-authored papers 12
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers 11
Ottawa Hospital Research Institute
Co-authored papers 11
The Ottawa Hospital Research Institute
Co-authored papers 9
University of Ottawa
Co-authored papers 8
Ottawa Hospital Research Institute
Co-authored papers 8
Ottawa Hospital Research Institute, The Ottawa Hospital
Co-authored papers 7
The Ottawa Hospital/University of Ottawa
Co-authored papers 6
Ottawa Hospital Research Institute
Co-authored papers 4
Ottawa Hospital Research Institute
Co-authored papers 4
Leeds Institute of Medical Research at St James's, University of Leeds
Co-authored papers 4
Ottawa Hospital Research Institute
Co-authored papers 3
College of Applied Medical Sciences, University of Tabuk
Co-authored papers 3
The Institute of Cancer Research
Co-authored papers 2
Ottawa Hospital Research Institute
Co-authored papers 2
The Ottawa Hospital
Co-authored papers 2
Co-authored papers 2
University of Ottawa Heart Institute
Co-authored papers 1
Ottawa Hospital Research Institute
Co-authored papers 1
University of Ottawa
Co-authored papers 1
McGill University
Co-authored papers 1
Ottawa Hospital Research Institute
Co-authored papers 1
Ottawa Hospital Research Institute
Co-authored papers 1
University of California los angeles
Co-authored papers 1