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Author Details

Melike Lakadamyali
Center for Engineering Mechanobiology, University of Pennsylvania
2003
69
31
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35996026Aberrant chromatin reorganization in cells from diseased fibrous connective tissue in response to altered chemomechanical cues.Nat Biomed Eng2023
37159293Quantitative Single-Molecule Localization Microscopy.Annu Rev Biophys2023
37215010ECLiPSE: A Versatile Classification Technique for Structural and Morphological Analysis of Super-Resolution Microscopy Data.bioRxiv2023
36744380Myo19 tethers mitochondria to endoplasmic reticulum-associated actin to promote mitochondrial fission.J Cell Sci2023
34705476Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites.Mol Biol Cell2022
36220894MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution.Nat Struct Mol Biol2022
36253374Actin polymerization promotes invagination of flat clathrin-coated lattices in mammalian cells by pushing at lattice edges.Nat Commun2022
35063099Technological advances in super-resolution microscopy to study cellular processes.Mol Cell2022
35033775Single nucleosome tracking to study chromatin plasticity.Curr Opin Cell Biol2022
34929735Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches.Nucleic Acids Res2022
33440158Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation.Cell Rep2021
35663461Single-molecule localization microscopy.Nat Rev Methods Primers2021
33626344Distinct properties and functions of CTCF revealed by a rapidly inducible degron system.Cell Rep2021
33788586Cega: a single particle segmentation algorithm to identify moving particles in a noisy system.Mol Biol Cell2021
34675061Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes.Genes Dev2021
34632419A protocol to quantify chromatin compaction with confocal and super-resolution microscopy in cultured cells.STAR Protoc2021
34297911Transcription-mediated supercoiling regulates genome folding and loop formation.Mol Cell2021
34059826A pairwise distance distribution correction (DDC) algorithm to eliminate blinking-caused artifacts in SMLM.Nat Methods2021
33952699Tau forms oligomeric complexes on microtubules that are distinct from tau aggregates.Proc Natl Acad Sci U S A2021
34087211Shear forces induce ICAM-1 nanoclustering on endothelial cells that impact on T-cell migration.Biophys J2021
33181171Nucleosome Clutches are Regulated by Chromatin Internal Parameters.J Mol Biol2021
32123395Visualizing the genome in high resolution challenges our textbook understanding.Nat Methods2020
33377115Two-parameter single-molecule analysis for measurement of chromatin mobility.STAR Protoc2020
32574554Two-Parameter Mobility Assessments Discriminate Diverse Regulatory Factor Behaviors in Chromatin.Mol Cell2020
32596438Nuclear softening expedites interstitial cell migration in fibrous networks and dense connective tissues.Sci Adv2020
30567713Detyrosinated microtubules spatially constrain lysosomes facilitating lysosome-autophagosome fusion.J Cell Biol2019
31287868Super-resolution microscopy reveals how histone tail acetylation affects DNA compaction within nucleosomes in vivo.Nucleic Acids Res2019
31103226Quantifying Protein Copy Number in Super Resolution Using an Imaging-Invariant Calibration.Biophys J2019
30675035Using enhanced number and brightness to measure protein oligomerization dynamics in live cells.Nat Protoc2019
29294098(Po)STAC (Polycistronic SunTAg modified CRISPR) enables live-cell and fixed-cell super-resolution imaging of multiple genes.Nucleic Acids Res2018
29974518Silver Atomic Quantum Clusters of Three Atoms for Cancer Therapy: Targeting Chromatin Compaction to Increase the Therapeutic Index of Chemotherapy.Adv Mater2018
29949761NMDA Receptor Autoantibodies in Autoimmune Encephalitis Cause a Subunit-Specific Nanoscale Redistribution of NMDA Receptors.Cell Rep2018
30509979Excitation-multiplexed multicolor superresolution imaging with fm-STORM and fm-DNA-PAINT.Proc Natl Acad Sci U S A2018
30361699Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.Nat Cell Biol2018
29632027Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.J Cell Biol2018
28843811Super resolution imaging of chromatin in pluripotency, differentiation, and reprogramming.Curr Opin Genet Dev2017
284206723D motion of vesicles along microtubules helps them to circumvent obstacles in cells.J Cell Sci2017
29192024Eph-ephrin signaling modulated by polymerization and condensation of receptors.Proc Natl Acad Sci U S A2017
28650478A DNA origami platform for quantifying protein copy number in super-resolution.Nat Methods2017
28803781Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.Mol Cell2017
28844138TiO<sub>2</sub> Nanoparticle-Induced Oxidation of the Plasma Membrane: Importance of the Protein Corona.J Phys Chem B2017
26798067The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells.Proc Natl Acad Sci U S A2016
27705766Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes.Biophys J2016
27243266Functionalized Surfaces with Tailored Wettability Determine Influenza A Infectivity.ACS Appl Mater Interfaces2016
26963549Voices of biotech.Nat Biotechnol2016
25392198Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice.Brain2015
25896023Advanced microscopy methods for visualizing chromatin structure.FEBS Lett2015
25768910Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo.Cell2015
24166886Super-resolution microscopy: going live and going fast.Chemphyschem2014
25545548A microfluidic platform for correlative live-cell and super-resolution microscopy.PLoS One2014
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Collaborators

Howard Hughes Medical Institute, Harvard University
Co-authored papers 9
Co-authored papers 1
Leiden University Medical Center
Co-authored papers 1
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 1
Genentech Inc.
Co-authored papers 1
Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Institut Pasteur, Universite Paris Cite, France Institut Pasteur
Co-authored papers 1
Living Systems Institute, University of Exeter
Co-authored papers 1
Co-authored papers 1
John Innes Centre
Co-authored papers 1
Institute of Materials Research and Engineering
Co-authored papers 1
Wuhan University of Technology, PR China Shaoxing Institute for Advanced Research
Co-authored papers 1
Industrial Technology Research Institute
Co-authored papers 1
Institute of Epigenetics and Stem Cells (IES)
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
International Institute of Tropical Agriculture
Co-authored papers 1
IBM T.J. Watson Research Center
Co-authored papers 1
Co-authored papers 1
Columbia University
Co-authored papers 1
Stanford University
Co-authored papers 1
The University of Melbourne at the Peter Doherty Institute for Infection and Immunity
Co-authored papers 1
Massachusetts Institute of Technology
Co-authored papers 1
University of Pennsylvania Department of Pathology & Laboratory Medicine
Co-authored papers 1
University of Manchester
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Weizmann Institute of Science
Co-authored papers 1
Padua University and Hospital
Co-authored papers 1
Gladstone Institutes, University of California San Francisco
Co-authored papers 1
Institute for Stem Cell Science and Regenerative Medicine (InStem)
Co-authored papers 1
University of Trento
Co-authored papers 1