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Author Details

James H Doroshow
National Cancer Institute, National Institutes of Health
1974
477
85
PMIDPaper TitleJournal TitlePublished Year
38010394Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors.Cancer Chemother Pharmacol2024
38010394Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors.Cancer Chemother Pharmacol2024
36302173Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma.Clin Cancer Res2023
36302173Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma.Clin Cancer Res2023
37672694Atezolizumab for Advanced Alveolar Soft Part Sarcoma.N Engl J Med2023
37637936Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs.Cancer Res Commun2023
37550087Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource.Mol Cancer Ther2023
36960342Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images.Front Med (Lausanne)2023
37330147Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway.Free Radic Biol Med2023
37267580The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer.J Clin Oncol2023
36813886Evaluating the indotecan-neutropenia relationship in patients with solid tumors by population pharmacokinetic modeling and sigmoidal E<sub>max</sub> regressions.Cancer Chemother Pharmacol2023
37322121The NCI-MATCH trial: lessons for precision oncology.Nat Med2023
36870109Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo.Redox Biol2023
37045940DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors.Sci Rep2023
36662819National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH).Clin Cancer Res2023
37531248The New NCI Precision Medicine Trials.Clin Cancer Res2023
36525371Expanding access to early phase trials: the CATCH-UP.2020 experience.JNCI Cancer Spectr2023
37550087Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource.Mol Cancer Ther2023
37672694Atezolizumab for Advanced Alveolar Soft Part Sarcoma.N Engl J Med2023
37637936Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs.Cancer Res Commun2023
37531248The New NCI Precision Medicine Trials.Clin Cancer Res2023
37322121The NCI-MATCH trial: lessons for precision oncology.Nat Med2023
37045940DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors.Sci Rep2023
37267580The Childhood Cancer Data Initiative: Using the Power of Data to Learn From and Improve Outcomes for Every Child and Young Adult With Pediatric Cancer.J Clin Oncol2023
37330147Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway.Free Radic Biol Med2023
36960342Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images.Front Med (Lausanne)2023
36813886Evaluating the indotecan-neutropenia relationship in patients with solid tumors by population pharmacokinetic modeling and sigmoidal E<sub>max</sub> regressions.Cancer Chemother Pharmacol2023
36870109Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo.Redox Biol2023
36662819National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH).Clin Cancer Res2023
36525371Expanding access to early phase trials: the CATCH-UP.2020 experience.JNCI Cancer Spectr2023
34716194Clinical Activity of Single-Agent Cabozantinib (XL184), a Multi-receptor Tyrosine Kinase Inhibitor, in Patients with Refractory Soft-Tissue Sarcomas.Clin Cancer Res2022
35964611Early drug development in solid tumours: analysis of National Cancer Institute-sponsored phase 1 trials.Lancet2022
35876604Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs.Mol Cancer Ther2022
35689374Bilateral Pulmonary Embolism Masked by New-Onset Atrial Fibrillation with Rapid Ventricular Rate: The Role of Mechanical Thrombectomy.Am J Case Rep2022
35803440The beginning of GPX2 and 30 years later.Free Radic Biol Med2022
36068285Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors.NPJ Precis Oncol2022
359824533'-[<sup>18</sup>F]fluoro-3'-deoxythymidine ([<sup>18</sup>F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor.J Transl Med2022
35472132ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies.Cancer Res2022
34524425A cross-study analysis of drug response prediction in cancer cell lines.Brief Bioinform2022
35333495Patterns of Enrollment in Cancer Treatment Trials During the COVID-19 Pandemic at National Cancer Institute-Designated Cancer Centers.Cancer J2022
35237050PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components.Onco Targets Ther2022
34450618TPWshiny: an interactive R/Shiny app to explore cell line transcriptional responses to anti-cancer drugs.Bioinformatics2022
34716194Clinical Activity of Single-Agent Cabozantinib (XL184), a Multi-receptor Tyrosine Kinase Inhibitor, in Patients with Refractory Soft-Tissue Sarcomas.Clin Cancer Res2022
34996889Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment.Nat Commun2022
35263120Trends in Grade 5 Toxicity and Response in Phase I Trials in Hematologic Malignancy: 20-Year Experience From the Cancer Therapy Evaluation Program at the National Cancer Institute.J Clin Oncol2022
35803440The beginning of GPX2 and 30 years later.Free Radic Biol Med2022
35472132ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies.Cancer Res2022
35689374Bilateral Pulmonary Embolism Masked by New-Onset Atrial Fibrillation with Rapid Ventricular Rate: The Role of Mechanical Thrombectomy.Am J Case Rep2022
36068285Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors.NPJ Precis Oncol2022
35964611Early drug development in solid tumours: analysis of National Cancer Institute-sponsored phase 1 trials.Lancet2022
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Collaborators

Center for Cancer Research, National Cancer Institute
Co-authored papers 29
Frederick National Laboratory for Cancer Research, Inc.
Co-authored papers 18
Center for Cancer Research, National Cancer Institute
Co-authored papers 18
Mayo Clinic
Co-authored papers 14
University of California Davis Comprehensive Cancer Center
Co-authored papers 14
National Cancer Institute
Co-authored papers 14
University of Texas Southwestern Medical Center
Co-authored papers 13
Center for Cancer Research, National Cancer Institute
Co-authored papers 13
University of Chicago
Co-authored papers 9
National Cancer Institute, National Institutes of Health
Co-authored papers 9
Institute of Biomedical Engineering (IBME), University of Oxford
Co-authored papers 9
University of Chicago
Co-authored papers 8
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 8
Osteosarcoma Institute
Co-authored papers 8
University of Chicago
Co-authored papers 8
Argonne National Laboratory
Co-authored papers 8
National Cancer Institute, National Institutes of Health
Co-authored papers 8
National Cancer Institute
Co-authored papers 7
Center for Cancer Research, National Cancer Institute
Co-authored papers 7
National Cancer Institute
Co-authored papers 7
Translational Research Center, Inha University Hospital
Co-authored papers 6
Brody School of Medicine, East Carolina University
Co-authored papers 5
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 5
University of Texas MD Anderson Cancer Center
Co-authored papers 5
Institute of Genetics and Cancer, University of Edinburgh
Co-authored papers 4
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
Co-authored papers 4
USC Norris Comprehensive Cancer Center
Co-authored papers 4
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National Cancer Institute, National Institutes of Health
Co-authored papers 4
University of Chicago
Co-authored papers 4