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Author Details

Richard Simon
National Cancer Institute
1975
283
87
PMIDPaper TitleJournal TitlePublished Year
33082209Early 3+3 Trial Dose-Escalation Phase I Clinical Trial Design and Suitability for Immune Checkpoint Inhibitors.Clin Cancer Res2021
33928209Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial.JCO Precis Oncol2021
33082209Early 3+3 Trial Dose-Escalation Phase I Clinical Trial Design and Suitability for Immune Checkpoint Inhibitors.Clin Cancer Res2021
34592177Inappropriate censoring in Kaplan-Meier analyses.Lancet Oncol2021
33928209Molecular Profiling-Based Assignment of Cancer Therapy (NCI-MPACT): A Randomized Multicenter Phase II Trial.JCO Precis Oncol2021
34592177Inappropriate censoring in Kaplan-Meier analyses.Lancet Oncol2021
31304851Finding the intended use population for a new treatment.J Biopharm Stat2019
31757478A novel approach to assess real-world efficacy of cancer therapy in metastatic prostate cancer. Analysis of national data on Veterans treated with abiraterone and enzalutamide.Semin Oncol2019
35100721Review of Statistical Methods for Biomarker-Driven Clinical Trials.JCO Precis Oncol2019
31272507Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.J Immunother Cancer2019
31367787Identification of pharmacodynamic biomarkers and common molecular mechanisms of response to genotoxic agents in cancer cell lines.Cancer Chemother Pharmacol2019
31304851Finding the intended use population for a new treatment.J Biopharm Stat2019
35100721Review of Statistical Methods for Biomarker-Driven Clinical Trials.JCO Precis Oncol2019
31757478A novel approach to assess real-world efficacy of cancer therapy in metastatic prostate cancer. Analysis of national data on Veterans treated with abiraterone and enzalutamide.Semin Oncol2019
31272507Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.J Immunother Cancer2019
31367787Identification of pharmacodynamic biomarkers and common molecular mechanisms of response to genotoxic agents in cancer cell lines.Cancer Chemother Pharmacol2019
28520893Using Bayesian modeling in frequentist adaptive enrichment designs.Biostatistics2018
28877003New designs for basket clinical trials in oncology.J Biopharm Stat2018
28520893Using Bayesian modeling in frequentist adaptive enrichment designs.Biostatistics2018
30355619The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.Cancer Res2018
30652557D3Oncoprint: Stand-Alone Software to Visualize and Dynamically Explore Annotated Genomic Mutation Files.JCO Clin Cancer Inform2018
29642934Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment.Hum Genomics2018
30652557D3Oncoprint: Stand-Alone Software to Visualize and Dynamically Explore Annotated Genomic Mutation Files.JCO Clin Cancer Inform2018
30355619The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel.Cancer Res2018
29642934Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment.Hum Genomics2018
28877003New designs for basket clinical trials in oncology.J Biopharm Stat2018
27422621OpenGeneMed: a portable, flexible and customizable informatics hub for the coordination of next-generation sequencing studies in support of precision medicine trials.Brief Bioinform2017
28498733Immunotherapy is different: Implications for vaccine clinical trial design.Hum Vaccin Immunother2017
28795420Inference for multimarker adaptive enrichment trials.Stat Med2017
28795401Critical Review of Umbrella, Basket, and Platform Designs for Oncology Clinical Trials.Clin Pharmacol Ther2017
29162114A computational study of the inhibition mechanisms of P-glycoprotein mediated paclitaxel efflux by kinase inhibitors.BMC Syst Biol2017
29245008On the Design of Combination Cancer Therapy.Cell2017
29276373Longitudinal Transcriptional Response of Glycosylation-Related Genes, Regulators, and Targets in Cancer Cell Lines Treated With 11 Antitumor Agents.Cancer Inform2017
27422621OpenGeneMed: a portable, flexible and customizable informatics hub for the coordination of next-generation sequencing studies in support of precision medicine trials.Brief Bioinform2017
27979599Estimation of tumour regression and growth rates during treatment in patients with advanced prostate cancer: a retrospective analysis.Lancet Oncol2017
27582434Missing the Mark: Prostate Cancer Upgrading by Systematic Biopsy over Magnetic Resonance Imaging/Transrectal Ultrasound Fusion Biopsy.J Urol2017
28498733Immunotherapy is different: Implications for vaccine clinical trial design.Hum Vaccin Immunother2017
29276373Longitudinal Transcriptional Response of Glycosylation-Related Genes, Regulators, and Targets in Cancer Cell Lines Treated With 11 Antitumor Agents.Cancer Inform2017
29245008On the Design of Combination Cancer Therapy.Cell2017
29162114A computational study of the inhibition mechanisms of P-glycoprotein mediated paclitaxel efflux by kinase inhibitors.BMC Syst Biol2017
28795420Inference for multimarker adaptive enrichment trials.Stat Med2017
28795401Critical Review of Umbrella, Basket, and Platform Designs for Oncology Clinical Trials.Clin Pharmacol Ther2017
27979599Estimation of tumour regression and growth rates during treatment in patients with advanced prostate cancer: a retrospective analysis.Lancet Oncol2017
27582434Missing the Mark: Prostate Cancer Upgrading by Systematic Biopsy over Magnetic Resonance Imaging/Transrectal Ultrasound Fusion Biopsy.J Urol2017
26970120The Bayesian basket design for genomic variant-driven phase II trials.Semin Oncol2016
27347216Concerted changes in transcriptional regulation of genes involved in DNA methylation, demethylation, and folate-mediated one-carbon metabolism pathways in the NCI-60 cancer cell line panel in response to cancer drug treatment.Clin Epigenetics2016
26970120The Bayesian basket design for genomic variant-driven phase II trials.Semin Oncol2016
27130933Efficiency of Prostate Cancer Diagnosis by MR/Ultrasound Fusion-Guided Biopsy vs Standard Extended-Sextant Biopsy for MR-Visible Lesions.J Natl Cancer Inst2016
27214515Genomic Alteration-Driven Clinical Trial Designs in Oncology.Ann Intern Med2016
26602013Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial.J Mol Diagn2016
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Collaborators

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Co-authored papers 14
Co-authored papers 11
Mayo Clinic
Co-authored papers 10
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Co-authored papers 10
National Cancer Institute, National Institutes of Health
Co-authored papers 9
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Co-authored papers 8
National Cancer Institute
Co-authored papers 8
National Institute on Aging, National Institutes of Health
Co-authored papers 7
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National Cancer Institute, National Institutes of Health
Co-authored papers 7
Center for Cancer Research, National Cancer Institute
Co-authored papers 7
National Cancer Institute, National Institutes of Health
Co-authored papers 7
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 7
Institute for Biomedical Research August Pi I Sunyer
Co-authored papers 6
Institute of Biomedical Engineering (IBME), University of Oxford
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Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 5
Zhujiang Hospital, Southern Medical University
Co-authored papers 5
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Technical University of Munich
Co-authored papers 4
USA The Jackson Laboratory Cancer Center
Co-authored papers 4
University of Colorado School of Medicine
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Memorial Sloan Kettering Cancer Center
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Center for Cancer Research, National Cancer Institute
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College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
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Center for Cancer Research, National Cancer Institute, National Institutes of Health
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University of California San Diego
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University of Colorado School of Medicine
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