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Author Details

Michael Sattler
Technical University of Munich, Institute of Structural Biology
1991
297
62
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36678896Identification of Autophagy as a Functional Target Suitable for the Pharmacological Treatment of Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) In Vitro.Pharmaceutics2023
37805067Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.J Mol Biol2023
37957306Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation.Nat Struct Mol Biol2023
38065098SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.Cell Rep2023
37587144Pharmacological perturbation of the phase-separating protein SMNDC1.Nat Commun2023
37506698FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.Mol Cell2023
37288967Molecular Dynamics Simulations with Grand-Canonical Reweighting Suggest Cooperativity Effects in RNA Structure Probing Experiments.J Chem Theory Comput2023
37454201Structural basis for specific RNA recognition by the alternative splicing factor RBM5.Nat Commun2023
37380771Phase separation of FSP1 promotes ferroptosis.Nature2023
36973549Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins.Nat Methods2023
37406382Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template.Eur J Med Chem2023
37031320Extrinsic stabilization of antiviral ACE2-Fc fusion proteins targeting SARS-CoV-2.Commun Biol2023
36689472Deciphering the RRM-RNA recognition code: A computational analysis.PLoS Comput Biol2023
36641211Combining NMR, SAXS and SANS to characterize the structure and dynamics of protein complexes.Methods Enzymol2023
34676998Highly Accurate Filters to Flag Frequent Hitters in AlphaScreen Assays by Suggesting their Mechanism.Mol Inform2022
35763700<sup>19</sup>F-NMR Unveils the Ligand-Induced Conformation of a Catalytically Inactive Twisted Homodimer of tRNA-Guanine Transglycosylase.ACS Chem Biol2022
35760371Conformational Effects of a Cancer-Linked Mutation in Pri-miR-30c RNA.J Mol Biol2022
35667441Extended conformational states dominate the Hsp90 chaperone dynamics.J Biol Chem2022
35688849Characterization of SARS-CoV-2 replication complex elongation and proofreading activity.Sci Rep2022
36476511DNA damage independent inhibition of NF-κB transcription by anthracyclines.Elife2022
36437542Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14.Biol Chem2022
36038611Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma.Sci Rep2022
36263945Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery.J Med Chem2022
36194937Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma.Eur J Med Chem2022
35921415Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of <i>MALT1</i>.Sci Adv2022
35063133NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.Mol Cell2022
35166835Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1.Nucleic Acids Res2022
34893887Structural basis of DNA methylation-dependent site selectivity of the Epstein-Barr virus lytic switch protein ZEBRA/Zta/BZLF1.Nucleic Acids Res2022
34789007Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses.Circ Res2022
33147371The Charged Linker Modulates the Conformations and Molecular Interactions of Hsp90.Chembiochem2021
33547294Structural elements in the flexible tail of the co-chaperone p23 coordinate client binding and progression of the Hsp90 chaperone cycle.Nat Commun2021
33598926FARS1-related disorders caused by bi-allelic mutations in cytosolic phenylalanyl-tRNA synthetase genes: Look beyond the lungs!Clin Genet2021
33738974Facile Synthesis of a Croconaine-Based Nanoformulation for Optoacoustic Imaging and Photothermal Therapy.Adv Healthc Mater2021
33818106Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.J Med Chem2021
33784254Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling.J Clin Invest2021
34919431Client binding shifts the populations of dynamic Hsp90 conformations through an allosteric network.Sci Adv2021
34988071Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3-PEX19 Interaction.Front Cell Dev Biol2021
34764289A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes.Nat Commun2021
34376783A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity.Commun Biol2021
34605140PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.EMBO Rep2021
34597510Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents.J Chem Inf Model2021
34389706SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns.Nat Commun2021
34450223Generation of novel long-acting GLP-1R agonists using DARPins as a scaffold.Int J Pharm2021
33969602Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.EMBO Rep2021
34016966Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.Nat Commun2021
33937250Membrane Interactions of the Peroxisomal Proteins PEX5 and PEX14.Front Cell Dev Biol2021
34310942Molecular insights on CALX-CBD12 interdomain dynamics from MD simulations, RDCs, and SAXS.Biophys J2021
33948433Croconaine-based nanoparticles enable efficient optoacoustic imaging of murine brain tumors.Photoacoustics2021
33288957Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler.Nat Chem Biol2021
33049303Albumin-binding domain extends half-life of glucagon-like peptide-1.Eur J Pharmacol2021
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Collaborators

Gottfried Schatz Research Center, Medical University of Graz
Co-authored papers 25
University Grenoble Alpes, CNRS
Co-authored papers 10
Institut Pasteur
Co-authored papers 7
Institute for Advanced Study, Technical University Munich
Co-authored papers 4
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University of Leicester
Co-authored papers 2
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Co-authored papers 2
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University of Wurzburg
Co-authored papers 2
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Co-authored papers 2
University of Munich, German Center for Lung Research (DZL)
Co-authored papers 2
Center for Molecular Biology (ZMBH), Heidelberg University
Co-authored papers 2
Center for Integrated Protein Science, Technische Universitat Munchen
Co-authored papers 2
Technische Universitat Munchen (TUM)
Co-authored papers 2
Universitat Tubingen, Institut fur Arbeitsmedizin
Co-authored papers 2
University of California San Francisco
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Rutgers University
Co-authored papers 1
Leicester Institute of Structural and Chemical Biology, University of Leicester
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The University of Sheffield
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Institute of Integrative Biology, University of Liverpool
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Columbia University
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National Institutes of Health
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Zernike Institute for Advanced Materials, University of Groningen
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