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Author Details

Jayati Sengupta
Institute of Child Health
1982
60
19
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35930049The clinical relevance of native vitamin D in pediatric kidney disease.Pediatr Nephrol2023
35324173Ligand-Dependent Modulation of the Dynamics of Intracellular Loops Dictates Functional Selectivity of 5-HT<sub>2A</sub>R.J Chem Inf Model2022
35034725The role of membranes in function and dysfunction of intrinsically disordered amyloidogenic proteins.Adv Protein Chem Struct Biol2022
32649051Hibernating ribosomes exhibit chaperoning activity but can resist unfolded protein-mediated subunit dissociation.FEBS J2021
33761323Structural insights into the interplay of protein biogenesis factors with the 70S ribosome.Structure2021
33532719Integrative approaches in cryogenic electron microscopy: Recent advances in structural biology and future perspectives.iScience2021
34478701Hidden electrostatic energy contributions define dynamic allosteric communications within p53 during molecular recognition.Biophys J2021
33941845Conformational distortion in a fibril-forming oligomer arrests alpha-Synuclein fibrillation and minimizes its toxic effects.Commun Biol2021
33449359Dynamics and electrostatics define an allosteric druggable site within the receptor-binding domain of SARS-CoV-2 spike protein.FEBS Lett2021
31469412Comprehensive structural modeling and preparation of human 5-HT<sub>2A</sub> G-protein coupled receptor in functionally active form.Biopolymers2020
33659368Expression and Purification of Functionally Active Serotonin 5-HT<sub>2A</sub> Receptor in Insect Cells Using Low-titer Viral Stock.Bio Protoc2020
31845055Free vitamin D levels in steroid-sensitive nephrotic syndrome and healthy controls.Pediatr Nephrol2020
33188638Structure, dynamics and lipid interactions of serotonin receptors: excitements and challenges.Biophys Rev2020
32656435Heptameric Peptide Interferes with Amyloid-β Aggregation by Structural Reorganization of the Toxic Oligomers.ACS Omega2020
32270361Resveratrol as a nontoxic excipient stabilizes insulin in a bioactive hexameric form.J Comput Aided Mol Des2020
32163280Retrospect and Prospect of Single Particle Cryo-Electron Microscopy: The Class of Integral Membrane Proteins as an Example.J Chem Inf Model2020
30448945Structural modules of the stress-induced protein HflX: an outlook on its evolution and biological role.Curr Genet2019
31314496Tumor Suppressor p53-Mediated Structural Reorganization of the Transcriptional Coactivator p300.Biochemistry2019
29412102Cloning, Expression, Purification and Characterization of Oligomeric States of the Native 5HT2A G-Protein-Coupled Receptor.Protein Pept Lett2018
29930203The universally conserved GTPase HflX is an RNA helicase that restores heat-damaged <i>Escherichia coli</i> ribosomes.J Cell Biol2018
28725977The effect of vitamin D and calcium supplementation in pediatric steroid-sensitive nephrotic syndrome.Pediatr Nephrol2017
28963859Unfolded protein exhibits antiassociation activity toward the 50S subunit facilitating 70S ribosome dissociation.FEBS J2017
28984254Yield of Imaging Performed as per Indian Society of Pediatric Nephrology Guidelines in Children with Urinary Tract Infection.Indian Pediatr2017
27099964Mechanistic Insight into the Reactivation of BCAII Enzyme from Denatured and Molten Globule States by Eukaryotic Ribosomes and Domain V rRNAs.PLoS One2016
27060894Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity.J Mol Graph Model2016
26822933E. coli metabolic protein aldehyde-alcohol dehydrogenase-E binds to the ribosome: a unique moonlighting action revealed.Sci Rep2016
27102067A rare case of myelofibrosis secondary to juvenile idiopathic arthritis.Br J Haematol2016
26723252Disassembly of yeast 80S ribosomes into subunits is a concerted action of ribosome-assisted folding of denatured protein.Biochem Biophys Res Commun2016
22890513Outcome of severe steroid-dependent nephrotic syndrome treated with mycophenolate mofetil.Pediatr Nephrol2013
23708762Vitamin D in nephrotic syndrome remission: a case-control study.Pediatr Nephrol2013
23397219Structural insights into the mechanism of translational inhibition by the fungicide sordarin.J Comput Aided Mol Des2013
22384065Structural diversity in bacterial ribosomes: mycobacterial 70S ribosome structure reveals novel features.PLoS One2012
20643101Intrinsic molecular properties of the protein-protein bridge facilitate ratchet-like motion of the ribosome.Biochem Biophys Res Commun2010
20584915Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit.J Cell Biol2010
19122150Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis.Proc Natl Acad Sci U S A2009
18606549Exploration of parameters in cryo-EM leading to an improved density map of the E. coli ribosome.J Struct Biol2008
18644383Visualization of the eEF2-80S ribosome transition-state complex by cryo-electron microscopy.J Mol Biol2008
17434183Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments.J Mol Biol2007
18003906The process of mRNA-tRNA translocation.Proc Natl Acad Sci U S A2007
16682558Functional conformations of the L11-ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations.RNA2006
15680982The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer.FEBS Lett2005
15949441Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies.Mol Cell2005
15334071Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM.Nat Struct Mol Biol2004
15577927Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome.EMBO Rep2004
15226561Comparative evaluation of cefpodoxime versus cefixime in children with lower respiratory tract infections.Indian J Pediatr2004
12511960A cryo-electron microscopic study of ribosome-bound termination factor RF2.Nature2003
14566331Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy.Nat Struct Biol2003
12809609Study of the structural dynamics of the E coli 70S ribosome using real-space refinement.Cell2003
12859903Locking and unlocking of ribosomal motions.Cell2003
12093756Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.EMBO J2002
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Collaborators

Joachim Frank
Columbia University
Co-authored papers 18
Mikel Valle
Center for Cooperative Research in Biosciences (CIC bioGUNE)
Co-authored papers 7
Rajendra K Agrawal
School of Public Health, University at Albany
Co-authored papers 4
Haixiao Gao
Howard Hughes Medical Institute, Inc. at the Wadsworth Center
Co-authored papers 3
Scott M Stagg
Florida State University
Co-authored papers 2
Stephen C Harvey
University of Pennsylvania
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Michael S Chapman
University of Missouri
Co-authored papers 1
Andrei A Korostelev
RNA Therapeutics Institute, University of Massachusetts Chan Medical School
Co-authored papers 1
Patrick Van Roey
Center for Medical Sciences
Co-authored papers 1
Narayanan Eswar
University of California at San Francisco
Co-authored papers 1
Derek J Taylor
Case Western Reserve University
Co-authored papers 1
Elizabeth Villa
University of California San Diego, USA Howard Hughes Medical Institute
Co-authored papers 1
Christian M T Spahn
Institut fur Medizinische Physik und Biophysik, Charite-Universitatsmedizin Berlin
Co-authored papers 1
Release 1.2