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Author Details

Owen R Davies
Institute of Cell Biology, University of Edinburgh
2000
46
24
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36635604Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3.Nat Struct Mol Biol2023
37862414SYCP1 head-to-head assembly is required for chromosome synapsis in mouse meiosis.Sci Adv2023
37493353Protein target highlights in CASP15: Analysis of models by structure providers.Proteins2023
37159901Meiotic Chromosome Structure, the Synaptonemal Complex, and Infertility.Annu Rev Genomics Hum Genet2023
36946995The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein.J Cell Biol2023
37416798Molecular insights into LINC complex architecture through the crystal structure of a luminal trimeric coiled-coil domain of SUN1.Front Cell Dev Biol2023
36071143Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip.Commun Biol2022
33393904A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies.Elife2021
33502312SUMO is a pervasive regulator of meiosis.Elife2021
34880391Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12.Commun Biol2021
34262048A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.Nat Commun2021
34373646Structural basis of meiotic chromosome synaptic elongation through hierarchical fibrous assembly of SYCE2-TEX12.Nat Struct Mol Biol2021
32133991Extending the scope of coiled-coil crystal structure solution by AMPLE through improved ab initio modelling.Acta Crystallogr D Struct Biol2020
32023061Obtaining Tertiary Protein Structures by the ab Initio Interpretation of Small Angle X-ray Scattering Data.J Chem Theory Comput2020
33325825Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.Elife2020
32917591Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility.Sci Adv2020
33021498Helical ensembles outperform ideal helices in molecular replacement.Acta Crystallogr D Struct Biol2020
30607510Molecular structure of human synaptonemal complex protein SYCE1.Chromosoma2019
31442339Target highlights in CASP13: Experimental target structures through the eyes of their authors.Proteins2019
31220082Crossover recombination and synapsis are linked by adjacent regions within the N terminus of the Zip1 synaptonemal complex protein.PLoS Genet2019
31023827A molecular model for self-assembly of the synaptonemal complex protein SYCE3.J Biol Chem2019
30745144Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1.Dev Cell2019
29588430An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy.J Am Soc Nephrol2018
29915389Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly.Nat Struct Mol Biol2018
30559341Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1.Nat Commun2018
28287952Single-molecule observation of DNA compaction by meiotic protein SYCP3.Elife2017
26742086Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.Elife2016
27796301C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility.Nat Commun2016
25558984CtIP tetramer assembly is required for DNA-end resection and repair.Nat Struct Mol Biol2015
24950965A molecular model for the role of SYCP3 in meiotic chromosome organisation.Elife2014
23395635Tcf15 primes pluripotent cells for differentiation.Cell Rep2013
22870393Structural analysis of the human SYCE2-TEX12 complex provides molecular insights into synaptonemal complex assembly.Open Biol2012
21554938Single shot tetanus vaccine manufactured by a supercritical fluid encapsulation technology.Int J Pharm2011
20220147Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition.J Biol Chem2010
18046455Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.EMBO J2008
32907149Macroporous surface modified microparticles.Soft Matter2008
18558783Surface modification of microspheres with steric stabilizing and cationic polymers for gene delivery.Langmuir2008
18069079Applications of supercritical CO2 in the fabrication of polymer systems for drug delivery and tissue engineering.Adv Drug Deliv Rev2008
17515903Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats.Nat Struct Mol Biol2007
16388993Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.DNA Repair (Amst)2006
16814929Structural analysis and classification of native proteins from E. coli commonly co-purified by immobilised metal affinity chromatography.Biochim Biophys Acta2006
16914443A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange.Nucleic Acids Res2006
16524830Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery.Philos Trans R Soc Lond B Biol Sci2006
15588896The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying.J Control Release2005
15910422The assessment of hookworm calreticulin as a potential vaccine for necatoriasis.Parasite Immunol2005
10976527Synthesis and characterisation of polyamine-poly(ethylene glycol) constructs for DNA binding and gene delivery.Bioorg Med Chem2000
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Collaborators

Tom L Blundell
Heartand Lung Research Institute, University of Cambridge
Co-authored papers 4
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Co-authored papers 3
Krzysztof Fidelis
University of California davis
Co-authored papers 2
Andriy Kryshtafovych
University of California davis
Co-authored papers 2
George N Phillips
Rice University
Co-authored papers 2
Maya Topf
Leibniz-Institut fur Virologie (LIV)
Co-authored papers 2
John Moult
Institute for Bioscience and Biotechnology Research
Co-authored papers 2
Sovan Sarkar
CRUK MRC Oxford Institute for Radiation Oncology, University of Oxford
Co-authored papers 2
Neil Hunter
IDR/Westmead Institute for Medical Research
Co-authored papers 2
Torsten Schwede
University of Basel
Co-authored papers 2
Sean R Collins
University of California davis
Co-authored papers 1
Mitchell D Miller
Rice University
Co-authored papers 1
Paul N Barlow
University of Edinburgh
Co-authored papers 1
Nikhil Bhagwat
Howard Hughes Medical Institute, University of California at Davis
Co-authored papers 1
Sheena D'Arcy
The University of Texas at Dallas
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Mahmud K K Shivji
Medical Research Council Cancer Unit, University of Cambridge
Co-authored papers 1
Srujan Kopparapu
University of California Davis
Co-authored papers 1
Masaru Ito
Institute for Protein Research, Osaka University
Co-authored papers 1
David F Burke
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 1
Philip Poa
University of California Davis
Co-authored papers 1
Alexander Ditzel
University of California Davis
Co-authored papers 1
Yufeng Tong
University of Windsor
Co-authored papers 1
Meghan Mahalawat
University of California Davis
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Bruno Lemaitre
Global Health Institute, Ecole Polytechnique Federale de Lausanne (EPFL)
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Jeffrey R Johnson
Gladstone Institutes
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Release 1.2