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Author Details

Chao Wang
Gladstone Institutes
2011
17
17
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35063084Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.Cell2022
35413950Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.Nat Commun2022
33852912Reducing acetylated tau is neuroprotective in brain injury.Cell2021
33854069Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.Nat Commun2021
31906970Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.Mol Neurodegener2020
30735499Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.PLoS Biol2019
31367015Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes.Nat Genet2019
29028540Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases.Curr Opin Neurobiol2018
29924488Transcription Factor-Mediated Differentiation of Human iPSCs into Neurons.Curr Protoc Cell Biol2018
29198827Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes.Stem Cell Reports2017
28966121Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.Stem Cell Reports2017
27041503Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Neuron2016
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
25261995Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.Nat Med2014
23371364Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.Acta Neuropathol2013
23024364Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein.J Biol Chem2012
22051244Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.J Neuroinflammation2011
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