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Author Details

Allen M Spiegel
Albert Einstein College of Medicine
1969
354
96
PMIDPaper TitleJournal TitlePublished Year
29337307A double negative: inhibition of hepatic Gi signaling improves glucose homeostasis.J Clin Invest2018
29337307A double negative: inhibition of hepatic Gi signaling improves glucose homeostasis.J Clin Invest2018
26994139Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.J Biol Chem2016
26994139Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.J Biol Chem2016
26019216Research in academic medical centers: two threats to sustainable support.Sci Transl Med2015
26052899The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).Endocrinology2015
26019216Research in academic medical centers: two threats to sustainable support.Sci Transl Med2015
26052899The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).Endocrinology2015
23802519G proteins--the disease spectrum expands.N Engl J Med2013
23802519G proteins--the disease spectrum expands.N Engl J Med2013
23874014The stem cell wars: a dispatch from the front.Trans Am Clin Climatol Assoc2013
23874014The stem cell wars: a dispatch from the front.Trans Am Clin Climatol Assoc2013
22232093'Personalized medicine' to identify genetic risks for type 2 diabetes and focus prevention: can it fulfill its promise?Health Aff (Millwood)2012
22232093'Personalized medicine' to identify genetic risks for type 2 diabetes and focus prevention: can it fulfill its promise?Health Aff (Millwood)2012
21448150Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors.Nat Rev Clin Oncol2011
21448150Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors.Nat Rev Clin Oncol2011
20520019Commentary: new guidelines for NIH peer review: improving the system or undermining it?Acad Med2010
21167386Future diagnostic and therapeutic trends in endocrine cancers.Semin Oncol2010
20520019Commentary: new guidelines for NIH peer review: improving the system or undermining it?Acad Med2010
21167386Future diagnostic and therapeutic trends in endocrine cancers.Semin Oncol2010
19208834Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.Cancer Res2009
19208834Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.Cancer Res2009
18310293Parathyroid tumor development involves deregulation of homeobox genes.Endocr Relat Cancer2008
18310293Parathyroid tumor development involves deregulation of homeobox genes.Endocr Relat Cancer2008
17243861Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca(2+) receptor.J Bone Miner Res2007
17986833Inherited endocrine diseases involving G proteins and G protein-coupled receptors.Endocr Dev2007
17979873Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators.J Cell Mol Med2007
17356705Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation.Neoplasia2007
17299066The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations.J Clin Endocrinol Metab2007
17243861Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca(2+) receptor.J Bone Miner Res2007
16988000Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor.Mol Endocrinol2007
17986833Inherited endocrine diseases involving G proteins and G protein-coupled receptors.Endocr Dev2007
17979873Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators.J Cell Mol Med2007
17299066The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations.J Clin Endocrinol Metab2007
17356705Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation.Neoplasia2007
16988000Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor.Mol Endocrinol2007
16604156Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.PLoS Genet2006
16397572NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health.Nat Med2006
16735501A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.J Biol Chem2006
16604156Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.PLoS Genet2006
16930585Genetic interactions between Drosophila melanogaster menin and Jun/Fos.Dev Biol2006
16735501A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.J Biol Chem2006
16930585Genetic interactions between Drosophila melanogaster menin and Jun/Fos.Dev Biol2006
16397572NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health.Nat Med2006
15591042A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.J Biol Chem2005
15915376Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas.Ann Surg Oncol2005
15856061Obesity on the brain.Nat Neurosci2005
15591042A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.J Biol Chem2005
16002822Executive summary of the Strategic Plan for National Institutes of Health Obesity Research.Am J Clin Nutr2005
16001329Menin molecular interactions: insights into normal functions and tumorigenesis.Horm Metab Res2005
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Collaborators

Stephen J Marx
National Institutes of Digestive Disease and Kidney, National Institutes of Health
Co-authored papers 137
Francis S Collins
University of Michigan ann arbor
Co-authored papers 46
Settara C Chandrasekharappa
National Institutes of Health
Co-authored papers 40
Sunita K Agarwal
National Institute of Diabetes and Digestive and Kidney Diseases
Co-authored papers 35
Michael R Emmert-Buck
The Francis Crick Institute
Co-authored papers 21
Zhengping Zhuang
National Cancer Institute, National Institutes of Health
Co-authored papers 19
Irina A Lubensky
National Cancer Institute, National Institutes of Health
Co-authored papers 19
Lance A Liotta
Co-authored papers 18
William F Simonds
Co-authored papers 17
Peter C Scacheri
Case Western Reserve University School of Medicine
Co-authored papers 9
Robert J Lefkowitz
Co-authored papers 7
Pablo V Gejman
Co-authored papers 5
Kenneth A Jacobson
National Institutes of Health
Co-authored papers 4
Mark S Boguski
Precision Medicine Network Inc.
Co-authored papers 4
Alexander O Vortmeyer
Indiana University School of Medicine
Co-authored papers 3
Michael R Erdos
Center for Precision Health Research, National Human Genome Research Institute
Co-authored papers 2
Craig J Thomas
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Maria J Merino
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Elliot S Gershon
University of Chicago
Co-authored papers 2
Stephen M Hewitt
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Michael T Collins
National Institute of Dental and Craniofacial Research
Co-authored papers 2
Robert J Weil
Rhode Island Hospital
Co-authored papers 2
Edward H Oldfield
National Institutes of Health
Co-authored papers 1
Thomas Ried
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Jorge Silvio Gutkind
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Gregory Campbell
Co-authored papers 1
Robert C Smallridge
Mayo Clinic School of Medicine, Mayo Clinic
Co-authored papers 1
Kris Ylaya
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Ravi Iyengar
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Release 1.2