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Author Details

Gary W Williams
Scripps Clinic
1977
48
22
PMIDPaper TitleJournal TitlePublished Year
30077426Molecular mechanisms of autophagic memory in pathogenic T cells in human arthritis.J Autoimmun2018
27624289Increased autophagy in CD4<sup>+</sup> T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance.Eur J Immunol2016
25790160A genome sequencing program for novel undiagnosed diseases.Genet Med2015
20538127The editor's roundtable: effect of nonsteroidal anti-inflammatory drugs on blood pressure.Am J Cardiol2010
20816131AJC Editor's consensus: Selective and nonselective nonsteroidal anti-inflammatory drugs and cardiovascular risk.Am J Cardiol2010
19101156Discovery of 13-oxa prostaglandin analogs as antiglaucoma agents: synthesis and biological activity.Bioorg Med Chem2009
18929707The editor's roundtable: nonsteroidal antiinflammatory drugs and cardiovascular risk.Am J Cardiol2008
17419053Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity.Bioorg Med Chem Lett2007
16678642A comparison of valdecoxib and naproxen in the treatment of rheumatoid arthritis symptoms.Clin Ther2006
17076623Preclinical pharmacology of AL-12182, a new ocular hypotensive 11-oxa prostaglandin analog.J Ocul Pharmacol Ther2006
15857278Ocular hypotensive DP-class prostaglandin receptor affinities determined by quantitative autoradiography on human eye sections.J Ocul Pharmacol Ther2005
16282038An update on nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors.Curr Pain Headache Rep2005
16310447The Editor's roundtable: cyclooxygenase-2 inhibitors and cardiovascular risk.Am J Cardiol2005
15357985AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey.Bioorg Med Chem Lett2004
15684809Molecular pharmacology of the DP/EP2 class prostaglandin AL-6598 and quantitative autoradiographic visualization of DP and EP2 receptor sites in human eyes.J Ocul Pharmacol Ther2004
1518683115-Fluoro prostaglandin FP agonists: a new class of topical ocular hypotensives.Bioorg Med Chem2004
15482641Cloned human 5-HT1A receptor pharmacology determined using agonist binding and measurement of cAMP accumulation.J Pharm Pharmacol2004
12490597Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost, unoprostone, and other analogs via endogenous mouse, rat, and cloned human FP prostaglandin receptors.J Pharmacol Exp Ther2003
14733708Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in cultured cells.J Ocul Pharmacol Ther2003
14578406Pharmacological characterization of a serotonin receptor (5-HT7) stimulating cAMP production in human corneal epithelial cells.Invest Ophthalmol Vis Sci2003
14613272Comparing the efficacy of cyclooxygenase 2-specific inhibitors in treating osteoarthritis: appropriate trial design considerations and results of a randomized, placebo-controlled trial.Arthritis Rheum2003
12538087Bimatoprost (Lumigan((R))) is an agonist at the cloned human ocular FP prostaglandin receptor: real-time FLIPR-based intracellular Ca(2+) mobilization studies.Prostaglandins Leukot Essent Fatty Acids2003
119373633-Oxa-15-cyclohexyl prostaglandin DP receptor agonists as topical antiglaucoma agents.Bioorg Med Chem2002
11740958Bimatoprost and its free acid are prostaglandin FP receptor agonists.Eur J Pharmacol2001
11293555Comparison of once-daily and twice-daily administration of celecoxib for the treatment of osteoarthritis of the knee.Clin Ther2001
10772998Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: focus on DP class prostanoids.J Pharmacol Exp Ther2000
19078452Treatment of osteoarthritis with a once-daily dosing regimen of celecoxib: a randomized, controlled trial.J Clin Rheumatol2000
11082108Pharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligand.Br J Pharmacol2000
10454045[3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travoprost (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor.J Pharm Pharmacol1999
9694973Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data.J Pharmacol Exp Ther1998
9152393FP prostaglandin receptors mediating inositol phosphates generation and calcium mobilization in Swiss 3T3 cells: a pharmacological study.J Pharmacol Exp Ther1997
9211463A new chromatographic method for measurement of rubidium transport activities in cultured bovine retinal pigment epithelial cells.Ophthalmic Res1997
7566362Affinities of muscarinic drugs for [3H]N-methylscopolamine (NMS) and [3H]oxotremorine (OXO) binding to a mixture of M1-M4 muscarinic receptors: use of NMS/OXO-M ratios to group compounds into potential agonist, partial agonist, and antagonist classes.Neurochem Res1995
10150686Low back pain: cost-effective diagnosis and treatment.Contemp Intern Med1995
8483844Comparison of the pharmacokinetics and pharmacodynamics of the aldose reductase inhibitors, AL03152 (RS), AL03802 (R), and AL03803 (S).Pharm Res1993
25635159Vitamin A Homeostasis in the Diabetic Rat.J Clin Biochem Nutr1993
2199116Steroid-related osteonecrosis of the knee. Two case reports and a literature review.Clin Orthop Relat Res1990
2350604A simple, sensitive liquid chromatographic method for quantitation of D-galactose and D-glucose in blood plasma.Biomed Chromatogr1990
6203888Studies of the antibacterial effect of the scandium complex of enterochelin.J Antibiot (Tokyo)1984
6421256Weighted criteria for the diagnosis of systemic lupus erythematosus.Arch Intern Med1984
7460395Brain-reactive lymphocytotoxic antibody in the cerebrospinal fluid of patients with systemic lupus erythematosus: correlation with central nervous system involvement.Clin Immunol Immunopathol1981
7468611Cerebrospinal fluid antibodies to neuronal cells: association with neuropsychiatric manifestations of systemic lupus erythematosus.Am J Med1981
33680Ribavirin treatment in murine autoimmune disease. I. Therapeutic efficacy and effect on the immune response.Arthritis Rheum1979
84675Immunofluorescence studies of anti-T cell antibodies and T cells in systemic lupus erythematosus. Selective loss of brightly staining T cells in active disease.Arthritis Rheum1979
27199Study of the multiple factors in the pathogenesis of autoimmunity in New Zealand mice.Arthritis Rheum1978
637886Therapeutic studies in NZB/NZW mice. VI. Age-dependent effects of concanavalin A stimulated spleen cell supernate.Arthritis Rheum1978
352210Influenza immunization in systemic lupus eruthematosus. A double-blind trial.Ann Intern Med1978
299957Ribavirin: efficacy in the treatment of murine autoimmune disease.Science1977
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Collaborators

Co-authored papers 2
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The Scripps Research Translational Institute, The Scripps Research Institute
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University of California, Rady Children's Hospital San Diego
Co-authored papers 1
Scripps Clinic
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Fred Hutchinson Cancer Center
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University of California San Diego
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Universidade Federal de Sao Paulo
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Scripps Clinic Torrey Pines
Co-authored papers 1
University of California
Co-authored papers 1
University of California Los Angeles
Co-authored papers 1
1] The Scripps Translational Science Institute
Co-authored papers 1
Salk Institute of Biological Studies
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Co-authored papers 1
Scripps Clinic Medical Group
Co-authored papers 1
Scripps Science Institute
Co-authored papers 1
Allergy and Clinical Immunology, University of California at Davis
Co-authored papers 1
Scripps Clinic and Scripps Translational Science Institute
Co-authored papers 1
Scripps Clinic
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University of California los angeles
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1