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Author Details

Darryl R Overby
Imperial College London
2001
84
37
PMIDPaper TitleJournal TitlePublished Year
37358489Pressure Clamping During Ocular Perfusions Drives Nitric Oxide-Mediated Washout.Invest Ophthalmol Vis Sci2023
35129590Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.Invest Ophthalmol Vis Sci2022
35432302Emergent Temporal Signaling in Human Trabecular Meshwork Cells: Role of TRPV4-TRPM4 Interactions.Front Immunol2022
35525299Measurement of postmortem outflow facility using iPerfusion.Exp Eye Res2022
36845355Model of inverse bleb growth explains giant vacuole dynamics during cell mechanoadaptation.PNAS Nexus2022
36273576Segmental outflow dynamics in the trabecular meshwork of living mice.Exp Eye Res2022
32931425Infusion Mechanisms in Brain White Matter and Their Dependence on Microstructure: An Experimental Study of Hydraulic Permeability.IEEE Trans Biomed Eng2021
33532718The role of Piezo1 in conventional aqueous humor outflow dynamics.iScience2021
33634081<i>Smarce1</i> and <i>Tensin 4</i> Are Putative Modulators of Corneoscleral Stiffness.Front Bioeng Biotechnol2021
33253900The vital role for nitric oxide in intraocular pressure homeostasis.Prog Retin Eye Res2021
33418484Deletion of the gene encoding prostamide/prostaglandin F synthase reveals an important role in regulating intraocular pressure.Prostaglandins Leukot Essent Fatty Acids2021
33239414The role of EP<sub>2</sub> receptors in mediating the ultra-long-lasting intraocular pressure reduction by JV-GL1.Br J Ophthalmol2021
33439773The ocular pulse decreases aqueous humor outflow resistance by stimulating nitric oxide production.Am J Physiol Cell Physiol2021
32203982The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice.Invest Ophthalmol Vis Sci2020
33376757siRNA targeting Schlemm's canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model.Mol Ther Methods Clin Dev2020
32845955Aqueous Humor Outflow Requires Active Cellular Metabolism in Mice.Invest Ophthalmol Vis Sci2020
32672595The Effect of High-Intensity Focused Ultrasound on Aqueous Humor Dynamics in Patients with Glaucoma.Ophthalmol Glaucoma2020
32242066Shear Stress in Schlemm's Canal as a Sensor of Intraocular Pressure.Sci Rep2020
32407519Age and Menopause Effects on Ocular Compliance and Aqueous Outflow.Invest Ophthalmol Vis Sci2020
30958169A model of the oscillatory mechanical forces in the conventional outflow pathway.J R Soc Interface2019
31709244Measurement of Ocular Compliance Using iPerfusion.Front Bioeng Biotechnol2019
31588175Ultrastructural variability of the juxtacanalicular tissue along the inner wall of Schlemm's canal.Mol Vis2019
31473215Aqueous Humor Dynamics in Uveitic Eyes.Am J Ophthalmol2019
31351057Reduced humidity experienced by mice in vivo coincides with reduced outflow facility measured ex vivo.Exp Eye Res2019
31143498Detection of proteoglycan loss from articular cartilage using Brillouin microscopy, with applications to osteoarthritis.Biomed Opt Express2019
29190025Quantification of Scleral Biomechanics and Collagen Fiber Alignment.Methods Mol Biol2018
30065366Water content, not stiffness, dominates Brillouin spectroscopy measurements in hydrated materials.Nat Methods2018
29526795Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.Exp Eye Res2018
29631366Pharmacological regulation of outflow resistance distal to Schlemm's canal.Am J Physiol Cell Physiol2018
29654113Effect of phacoemulsification on facility of outflow.Br J Ophthalmol2018
26850315Unconventional aqueous humor outflow: A review.Exp Eye Res2017
28358961Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2017
28358962VEGF as a Paracrine Regulator of Conventional Outflow Facility.Invest Ophthalmol Vis Sci2017
28221702Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma.Adv Mater2017
28158775Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.Hum Mol Genet2017
28091584Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia.Sci Rep2017
29114841Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents.Invest Ophthalmol Vis Sci2017
28512791Peptide-Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite-Mediated Nitration.Adv Healthc Mater2017
28720436Direct measurement of pressure-independent aqueous humour flow using iPerfusion.Exp Eye Res2017
26949939Measurement of Outflow Facility Using iPerfusion.PLoS One2016
26689753Transport across Schlemm's canal endothelium and the blood-aqueous barrier.Exp Eye Res2016
27014939Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop.Endocrinology2016
26982549The Value of Mouse Models for Glaucoma Drug Discovery.J Ocul Pharmacol Ther2016
27085895Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes.Eur J Pharmacol2016
25223880Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction.Prog Retin Eye Res2015
26720486Physical Factors Affecting Outflow Facility Measurements in Mice.Invest Ophthalmol Vis Sci2015
26051991Animal models of glucocorticoid-induced glaucoma.Exp Eye Res2015
26040898Role of nitric oxide in murine conventional outflow physiology.Am J Physiol Cell Physiol2015
25450060Colocalization of outflow segmentation and pores along the inner wall of Schlemm's canal.Exp Eye Res2015
23721097The design and development of a high-throughput magneto-mechanostimulation device for cartilage tissue engineering.Tissue Eng Part C Methods2014
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Collaborators

Haiyan Gong
Boston University School of Medicine
Co-authored papers 8
Abbot F Clark
North Texas Eye Research Institute, University of North Texas Health Science Center
Co-authored papers 3
Sina Farsiu
Duke University
Co-authored papers 3
Joanne C Wen
Duke University
Co-authored papers 2
Colleen M McDowell
University of Wisconsin-Madison
Co-authored papers 2
Yutao Liu
Augusta University
Co-authored papers 2
Louis R Pasquale
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Steven Folz
Co-authored papers 2
Joel S Schuman
NYU Grossman School of Medicine
Co-authored papers 2
Mark H Ginsberg
University of California
Co-authored papers 1
Val C Sheffield
Carver College of Medicine, University of Iowa
Co-authored papers 1
Larry Kagemann
University of Pittsburgh
Co-authored papers 1
H Ishikawa
Mie University School of Medicine, NYU School of Medicine, New York Medical College, New York University School of Medicine, Oregon Health & Science University, Tufts University School of Medicine, University of Pittsburgh School of Medicine, University of Pittsburgh School of Mediine
Co-authored papers 1
Ian A Sigal
University of Pittsburgh
Co-authored papers 1
Gadi Wollstein
NYU College of Arts and Sciences
Co-authored papers 1
Bo Wang
Institute of Biophysics, Chinese Academy of Sciences
Co-authored papers 1
Hao F Zhang
Northwestern University
Co-authored papers 1
Brian C Leonard
Co-authored papers 1
Ningli Wang
Beijing Tongren Hospital, Capital Medical University
Co-authored papers 1
J Crawford Downs
University of Alabama at Birmingham
Co-authored papers 1
Paul Russell
The Scripps Research Institute
Co-authored papers 1
Andrew W Francis
University of California san francisco
Co-authored papers 1
Murray Johnstone
University of Washington
Co-authored papers 1
Release 1.2