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Author Details

Steven J Isakoff
Massachusetts General Hospital
1995
127
52
PMIDPaper TitleJournal TitlePublished Year
37922440Virtual Molecular and Precision Medicine Clinic to Improve Access to Clinical Trials for Patients With Metastatic Breast Cancer: An Academic/Community Collaboration.JCO Oncol Pract2024
37916958Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.Cancer Discov2024
38060199First-Line Ipatasertib, Atezolizumab, and Taxane Triplet for Metastatic Triple-Negative Breast Cancer: Clinical and Biomarker Results.Clin Cancer Res2024
38092228Response-guided neoadjuvant sacituzumab govitecan for localized triple-negative breast cancer: results from the NeoSTAR trial.Ann Oncol2024
36865255Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and tumor microenvironment, overcoming multiple obstacles of CAR T therapy for solid tumors.Res Sq2023
37714830Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment.Nat Commun2023
37076495Utilizing cell-free DNA to predict risk of developing brain metastases in patients with metastatic breast cancer.NPJ Breast Cancer2023
37103597Feasibility of introducing a smartphone navigation application into the care of breast cancer patients (The FIONA Study).Breast Cancer Res Treat2023
36643653Adjuvant trastuzumab and vinorelbine for early-stage HER2+ breast cancer.Ther Adv Med Oncol2023
36772966Therapeutic Role of Tamoxifen for Triple-Negative Breast Cancer: Leveraging the Interaction Between ERβ and Mutant p53.Oncologist2023
34752147Immunogenicity and Reactogenicity of SARS-CoV-2 Vaccines in Patients With Cancer: The CANVAX Cohort Study.J Clin Oncol2022
35441995Pilot study to assess prolonged overnight fasting in breast cancer survivors (longfast).Breast Cancer Res Treat2022
35671420Breast Medical Oncologists' Perspectives of Telemedicine for Breast Cancer Care: A Survey Study.JCO Oncol Pract2022
35788722Neoadjuvant study of niraparib in patients with HER2-negative, BRCA-mutated, resectable breast cancer.Nat Cancer2022
35852437Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network.Oncologist2022
35592673An Initial Evaluation of Human Plasma cMLC-1: A Potential Protein Biomarker for Trastuzumab-Induced Cardiotoxicity, Breast Cancer Screening and Progression.Front Oncol2022
35714678The Evolving Role of Neoadjuvant Therapy for Operable Breast Cancer.J Natl Compr Canc Netw2022
35714673Breast Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2022
36450763Treatment discontinuation, patient-reported toxicities and quality-of-life by age following trastuzumab emtansine or paclitaxel/trastuzumab (ATEMPT).NPJ Breast Cancer2022
35931884Author Correction: Neoadjuvant study of niraparib in patients with HER2-negative, BRCA-mutated, resectable breast cancer.Nat Cancer2022
36051470Immunogenicity of SARS-CoV-2 vaccines in patients with breast cancer.Ther Adv Med Oncol2022
34860318Ipatasertib plus paclitaxel for PIK3CA/AKT1/PTEN-altered hormone receptor-positive HER2-negative advanced breast cancer: primary results from cohort B of the IPATunity130 randomized phase 3 trial.Breast Cancer Res Treat2022
34907082Functional Mapping of AKT Signaling and Biomarkers of Response from the FAIRLANE Trial of Neoadjuvant Ipatasertib plus Paclitaxel for Triple-Negative Breast Cancer.Clin Cancer Res2022
35173164Cardiac outcomes of subjects on adjuvant trastuzumab emtansine vs paclitaxel in combination with trastuzumab for stage I HER2-positive breast cancer (ATEMPT) study (TBCRC033): a randomized controlled trial.NPJ Breast Cancer2022
34990776Local Therapy Outcomes and Toxicity From the ATEMPT Trial (TBCRC 033): A Phase II Randomized Trial of Adjuvant Trastuzumab Emtansine Versus Paclitaxel in Combination With Trastuzumab in Women With Stage I HER2-Positive Breast Cancer.Int J Radiat Oncol Biol Phys2022
33153384The adjuvant use of capecitabine for residual disease following pre-operative chemotherapy for breast cancer: Challenges applying CREATE-X to a US population.J Oncol Pharm Pract2021
33713742A Phase 1 Dose-Escalation Trial of Radiation Therapy and Concurrent Cisplatin for Stage II and III Triple-Negative Breast Cancer.Int J Radiat Oncol Biol Phys2021
33761455Clinical Outcomes With Abemaciclib After Prior CDK4/6 Inhibitor Progression in Breast Cancer: A Multicenter Experience.J Natl Compr Canc Netw2021
33504549Tumor Tissue- versus Plasma-based Genotyping for Selection of Matched Therapy and Impact on Clinical Outcomes in Patients with Metastatic Breast Cancer.Clin Cancer Res2021
34994617Phase II Single-Arm Study to Assess Trastuzumab and Vinorelbine in Advanced Breast Cancer Patients With HER2-Negative Tumors and HER2-Positive Circulating Tumor Cells.JCO Precis Oncol2021
34794122NCCN Guidelines® Insights: Breast Cancer, Version 4.2021.J Natl Compr Canc Netw2021
34404686Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer.Cancer Discov2021
34417675Phase II trial of veliparib and temozolomide in metastatic breast cancer patients with and without BRCA1/2 mutations.Breast Cancer Res Treat2021
34077270Adjuvant Trastuzumab Emtansine Versus Paclitaxel in Combination With Trastuzumab for Stage I HER2-Positive Breast Cancer (ATEMPT): A Randomized Clinical Trial.J Clin Oncol2021
34302589A phase II study of efficacy, toxicity, and the potential impact of genomic alterations on response to eribulin mesylate in combination with trastuzumab and pertuzumab in women with human epidermal growth factor receptor 2 (HER2)+ metastatic breast cancer.Breast Cancer Res Treat2021
34349115Phase 1b clinical trial of ado-trastuzumab emtansine and ribociclib for HER2-positive metastatic breast cancer.NPJ Breast Cancer2021
34120223Chemotherapy-related amenorrhea (CRA) after adjuvant ado-trastuzumab emtansine (T-DM1) compared to paclitaxel in combination with trastuzumab (TH) (TBCRC033: ATEMPT Trial).Breast Cancer Res Treat2021
33978307Phase II and Biomarker Study of Cabozantinib in Metastatic Triple-Negative Breast Cancer Patients.Oncologist2021
34168046RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer.Clin Cancer Res2021
31492767Patient Preferences for Use of Archived Biospecimens from Oncology Trials When Adequacy of Informed Consent Is Unclear.Oncologist2020
35050782Rising Circulating Tumor DNA As a Molecular Biomarker of Early Disease Progression in Metastatic Breast Cancer.JCO Precis Oncol2020
32101669Case 7-2020: A 52-Year-Old Man with a Mass in the Left Breast.N Engl J Med2020
32046998Pathologic Complete Response after Neoadjuvant Chemotherapy and Impact on Breast Cancer Recurrence and Survival: A Comprehensive Meta-analysis.Clin Cancer Res2020
32097092TBCRC 031: Randomized Phase II Study of Neoadjuvant Cisplatin Versus Doxorubicin-Cyclophosphamide in Germline <i>BRCA</i> Carriers With HER2-Negative Breast Cancer (the INFORM trial).J Clin Oncol2020
31796517Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and <i>BRCA1/2</i> Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis.Clin Cancer Res2020
32610007Case 22-2020: A 62-Year-Old Woman with Early Breast Cancer during the Covid-19 Pandemic.N Engl J Med2020
32712878A system for risk stratification and prioritization of breast cancer surgeries delayed by the COVID-19 pandemic: preparing for re-entry.Breast Cancer Res Treat2020
32571788Identification of Somatically Acquired <i>BRCA1/2</i> Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer.Clin Cancer Res2020
32700046Integration of Physician and Nursing Professional Efforts to Deliver Supportive Scalp Cooling Care to Oncology Patients at Risk for Alopecia.Oncol Ther2020
32417409Optimizing Radiation Therapy to Boost Systemic Immune Responses in Breast Cancer: A Critical Review for Breast Radiation Oncologists.Int J Radiat Oncol Biol Phys2020
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Collaborators

Massachusetts General Hospital Cancer Center
Co-authored papers 30
Dana-Farber Cancer Institute
Co-authored papers 20
Dana-Farber Cancer Institute
Co-authored papers 18
Vanderbilt University Medical Center
Co-authored papers 16
Co-authored papers 14
Co-authored papers 14
The University of Texas MD Anderson Cancer Center
Co-authored papers 12
Dana-Farber Cancer Institute
Co-authored papers 10
Massachusetts General Hospital
Co-authored papers 9
Massachusetts General Hospital
Co-authored papers 9
Co-authored papers 8
Co-authored papers 8
University of California
Co-authored papers 8
Mayo Clinic
Co-authored papers 8
Co-authored papers 7
Memorial Sloan Kettering Cancer Center, USA American Society of Clinical Oncology
Co-authored papers 7
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 7
University of California San Diego
Co-authored papers 6
Co-authored papers 5
Massachusetts General Hospital
Co-authored papers 5
Co-authored papers 4
Dartmouth Cancer Center
Co-authored papers 4
Co-authored papers 4
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 4
Mayo Clinic
Co-authored papers 4
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Massachusetts General Hospital/Harvard Medical School
Co-authored papers 3
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Co-authored papers 3