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Author Details

Huiying Li
University of California irvine
1991
175
51
PMIDPaper TitleJournal TitlePublished Year
37433128Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors.J Med Chem2023
35248417The impact of fixed orthodontic appliances and clear aligners on the oral microbiome and the association with clinical parameters: A longitudinal comparative study.Am J Orthod Dentofacial Orthop2022
357722852-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.Bioorg Med Chem2022
35427129A Rigorous Method for Identifying a One-Dimensional Reaction Coordinate in Complex Molecules.J Chem Theory Comput2022
36459640Exact reaction coordinates for flap opening in HIV-1 protease.Proc Natl Acad Sci U S A2022
35951409Origin of Protein Quake: Energy Waves Conducted by a Precise Mechanical Machine.J Chem Theory Comput2022
36346639Reactive Vortexes in a Naturally Activated Process: Non-Diffusive Rotational Fluxes at Transition State Uncovered by Persistent Homology.J Phys Chem B2022
35250944Integrative Assessments on Molecular Taxonomy of <i>Acidiferrobacter thiooxydans</i> ZJ and Its Environmental Adaptation Based on Mobile Genetic Elements.Front Microbiol2022
34152261YhjC is a novel transcriptional regulator required for Shigella flexneri virulence.Virulence2021
32397065MG-MLST: Characterizing the Microbiome at the Strain Level in Metagenomic Data.Microorganisms2020
31673077The subgingival microbiome associated with periodontitis in type 2 diabetes mellitus.ISME J2020
31941813Porphyrin Production and Regulation in Cutaneous Propionibacteria.mSphere2020
33102255Cervical-Vaginal Microbiome and Associated Cytokine Profiles in a Prospective Study of HPV 16 Acquisition, Persistence, and Clearance.Front Cell Infect Microbiol2020
32991841Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.Cell2020
32843557Cervicovaginal Microbiome Composition Is Associated with Metabolic Profiles in Healthy Pregnancy.mBio2020
32895384Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring.Nat Commun2020
32242146Author Correction: The balance of metagenomic elements shapes the skin microbiome in acne and health.Sci Rep2020
32302123First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.J Med Chem2020
32543022Caenorhabditis elegans mounts a p38 MAPK pathway-mediated defence to Cutibacterium acnes infection.Cell Microbiol2020
30592215Correction to Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.J Med Chem2019
31431508A Microbiome-Based Index for Assessing Skin Health and Treatment Effects for Atopic Dermatitis in Children.mSystems2019
30802056Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.J Med Chem2019
30843879Propionibacterium acnes-induced immunopathology correlates with health and disease association.JCI Insight2019
30633512Correction to Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.J Med Chem2019
30632097Acne, the Skin Microbiome, and Antibiotic Treatment.Am J Clin Dermatol2019
29020266Propionibacterium avidum: A Virulent Pathogen Causing Hip Periprosthetic Joint Infection.Clin Infect Dis2018
30335983Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides.Biochemistry2018
29410379Methicillin-Resistant Staphylococcus aureus Colonization Is Associated with Decreased Skin Commensal Bacteria in Atopic Dermatitis.J Invest Dermatol2018
26988937Shaping of cutaneous function by encounters with commensals.J Physiol2017
28422508Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.J Med Chem2017
29130432Corrigendum: Proposal to reclassify Propionibacterium acnes type I as Propionibacterium acnes subsp. acnes subsp. nov. and Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov.Int J Syst Evol Microbiol2017
29091437Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.J Med Chem2017
28776992Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.J Med Chem2017
27890696Nitric oxide synthase and structure-based inhibitor design.Nitric Oxide2017
27050842Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.J Med Chem2016
26448477Elucidating nitric oxide synthase domain interactions by molecular dynamics.Protein Sci2016
27670798Emendation of Propionibacterium acnes subsp. acnes (Deiko et al. 2015) and proposal of Propionibacterium acnes type II as Propionibacterium acnes subsp. defendens subsp. nov.Int J Syst Evol Microbiol2016
28066812The Denture-Associated Oral Microbiome in Health and Stomatitis.mSphere2016
28000755The balance of metagenomic elements shapes the skin microbiome in acne and health.Sci Rep2016
27303708Strain-Level Differences in Porphyrin Production and Regulation in Propionibacterium acnes Elucidate Disease Associations.mSphere2016
27474122The skin microbiome is different in pediatric versus adult atopic dermatitis.J Allergy Clin Immunol2016
27555369Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis.Sci Rep2016
27250740Electrostatic Control of Isoform Selective Inhibitor Binding in Nitric Oxide Synthase.Biochemistry2016
26807481Correction to Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.J Med Chem2016
25522110Structure-based design of bacterial nitric oxide synthase inhibitors.J Med Chem2015
26469213Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.J Med Chem2015
26283260The diversity and host interactions of Propionibacterium acnes bacteriophages on human skin.ISME J2015
261207332-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.J Med Chem2015
26091171Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus.Chem Biol2015
26035438Probing the Hydrogen Bonding of the Ferrous-NO Heme Center of nNOS by Pulsed Electron Paramagnetic Resonance.J Phys Chem A2015
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Collaborators

University of California los angeles
Co-authored papers 5
university of california los angeles
Co-authored papers 5
The Genome Center at Washington University, Washington University School of Medicine
Co-authored papers 3
The Genome Institute at Washington University
Co-authored papers 3
and the California NanoSystems Institute, University of California los angeles
Co-authored papers 2
University of Wisconsin
Co-authored papers 2
University of California
Co-authored papers 2
David Geffen School of Medicine at University of California los angeles
Co-authored papers 2
University of California Riverside School of Medicine
Co-authored papers 1
University of California berkeley
Co-authored papers 1
University of Cincinnati College of Medicine
Co-authored papers 1
Cedars-Sinai Medical Center
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
The J. Craig Venter Institute.
Co-authored papers 1
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 1
Instituto Oswaldo Cruz
Co-authored papers 1
University of California san francisco
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Co-authored papers 1
European Cancer Stem Cell Research Institute, Cardiff University
Co-authored papers 1
University of California berkeley
Co-authored papers 1
university of california san diego School of Medicine
Co-authored papers 1
J. Craig Venter Institute
Co-authored papers 1
Harvard T.H. Chan School of Public Health
Co-authored papers 1
Northwestern University
Co-authored papers 1
Ludwig Institute for Cancer Research
Co-authored papers 1
The University of Southern California
Co-authored papers 1
J. Craig Venter Institute
Co-authored papers 1