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Author Details

Olaf Witt
Hopp Children's Cancer Center Heidelberg (KiTZ)
1993
231
63
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37978284The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.Nat Med2024
37944912Pediatric low-grade glioma: State-of-the-art and ongoing challenges.Neuro Oncol2024
37978284The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.Nat Med2024
37875569Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.Nat Med2024
37944912Pediatric low-grade glioma: State-of-the-art and ongoing challenges.Neuro Oncol2024
37875569Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.Nat Med2024
35977048BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.Neuro Oncol2023
36181342ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P-glycoprotein.Mol Oncol2023
35882450The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.Neuro Oncol2023
36255618Evaluation of Antitumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft Model.Methods Mol Biol2023
35977048BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.Neuro Oncol2023
37738646Optimizing preclinical pediatric low-grade glioma models for meaningful clinical translation.Neuro Oncol2023
37733309Dabrafenib plus Trametinib in Pediatric Glioma with <i>BRAF</i> V600 Mutations.N Engl J Med2023
37643378Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory <i>BRAF</i> V600-Mutant Pediatric High-Grade Glioma.J Clin Oncol2023
37783879Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells.J Neurooncol2023
37776353Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.Acta Neuropathol2023
36959034Corrigendum to 'Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry' [Eur J Cancer 180 (2023) 71-84].Eur J Cancer2023
36639156Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.J Immunother Cancer2023
37075810LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.Neuro Oncol2023
37260252Neurosurgical morbidity in pediatric supratentorial midline low-grade glioma: Results from the German LGG studies.Int J Cancer2023
36871657Cerebellar Mutism Syndrome After Posterior Fossa Tumor Surgery in Children-A Retrospective Single-Center Study.World Neurosurg2023
37441736Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.Clin Pharmacol Ther2023
37379234Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.Neuro Oncol2023
37308967Beyond germline genetic testing - heterozygous pathogenic variants in PMS2 in two children with Osteosarcoma and Ependymoma.Hered Cancer Clin Pract2023
37183219Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.J Neurooncol2023
36933012Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions.Acta Neuropathol2023
36542877Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.Eur J Cancer2023
36928815Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.Nat Med2023
37364231Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.JCO Precis Oncol2023
36459208Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.Acta Neuropathol2023
37500667MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.Nat Commun2023
37541273Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study.Lancet Oncol2023
37783879Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells.J Neurooncol2023
37738646Optimizing preclinical pediatric low-grade glioma models for meaningful clinical translation.Neuro Oncol2023
37776353Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.Acta Neuropathol2023
37733309Dabrafenib plus Trametinib in Pediatric Glioma with <i>BRAF</i> V600 Mutations.N Engl J Med2023
37541273Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study.Lancet Oncol2023
37500667MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.Nat Commun2023
37643378Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory <i>BRAF</i> V600-Mutant Pediatric High-Grade Glioma.J Clin Oncol2023
36959034Corrigendum to 'Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry' [Eur J Cancer 180 (2023) 71-84].Eur J Cancer2023
37183219Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.J Neurooncol2023
37379234Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.Neuro Oncol2023
37441736Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.Clin Pharmacol Ther2023
37308967Beyond germline genetic testing - heterozygous pathogenic variants in PMS2 in two children with Osteosarcoma and Ependymoma.Hered Cancer Clin Pract2023
37075810LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.Neuro Oncol2023
37364231Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.JCO Precis Oncol2023
37260252Neurosurgical morbidity in pediatric supratentorial midline low-grade glioma: Results from the German LGG studies.Int J Cancer2023
36542877Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.Eur J Cancer2023
36871657Cerebellar Mutism Syndrome After Posterior Fossa Tumor Surgery in Children-A Retrospective Single-Center Study.World Neurosurg2023
36639156Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.J Immunother Cancer2023
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Collaborators

Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 98
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 91
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 74
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 58
Co-authored papers 55
Co-authored papers 45
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 38
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 37
Co-authored papers 34
German Cancer Research Center (DKFZ)
Co-authored papers 34
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 33
Co-authored papers 30
Charite University Medicine Berlin
Co-authored papers 27
Co-authored papers 26
Co-authored papers 25
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 24
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 22
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg University
Co-authored papers 21
The Hospital for Sick Children
Co-authored papers 21
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 20
N.N. Burdenko Neurosurgical Institute
Co-authored papers 19
St Jude Children's Research Hospital
Co-authored papers 19
Co-authored papers 19
University Medical Center Hamburg-Eppendorf
Co-authored papers 19
Co-authored papers 18
Co-authored papers 18
Co-authored papers 17
Co-authored papers 17
Co-authored papers 17
Amsterdam University Medical Centers location AMC
Co-authored papers 16