Author details

Full Name

Shozeb Haider

Affiliation

ORCID

Career Start Year

2002

Papers

146

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36985425	The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer.		2023
37850746	Natural protein engineering in the Î©-loop: the role of Y221 in ceftazidime and ceftolozane resistance in -derived cephalosporinase.		2023
36655992	Future COVID19 surges prediction based on SARS-CoV-2 mutations surveillance.		2023
36826989	Gating interactions steer loop conformational changes in the active site of the L1 metallo-Î²-lactamase.		2023
36879130	Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts.	Nat Med	2023
36628526	Optimizing a therapeutic humanized follicle-stimulating hormone-blocking antibody formulation by protein thermal shift assay.	Ann N Y Acad Sci	2023
37253099	Rare variants in ANO1, encoding a calcium-activated chloride channel, predispose to moyamoya disease.	Brain	2023
37126322	Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.	JAMA Neurol	2023
34715668	Genomic approaches to improve the clinical diagnosis and management of patients with congenital hydrocephalus.	Journal of Neurosurgery: Pediatrics	2022
36244453	Control of cell surface expression of GABA receptors by a conserved region at the end of the N-terminal extracellular domain of receptor subunits.	Journal of Biological Chemistry	2022
35456614	In Vivo Investigation of (2-Hydroxypropyl)-Î²-cyclodextrin-Based Formulation of Spironolactone in Aqueous Solution for Paediatric Use.	Pharmaceutics	2022
36293303	Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening.	International Journal of Molecular Sciences	2022
35678782	Rare pathogenic variants in WNK3 cause X-linked intellectual disability.	Genet Med	2022
35792385	Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance.	European Journal of Medicinal Chemistry	2022
36412088	Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other Î²-coronaviruses by simulations and crystallography.	eLife	2022
36454409	The blood-to-plasma ratio and predicted GABA-binding affinity of designer benzodiazepines.	Forensic Toxicology	2022
34989224	Mechanistic Insights into the Ligand-Induced Unfolding of an RNA G-Quadruplex.	Journal of the American Chemical Society	2022
35253434	Triggered Assembly of a DNA-Based Membrane Channel.	Journal of the American Chemical Society	2022
34604302	Inter-Subunit Dynamics Controls Tunnel Formation During the Oxygenation Process in Hemocyanin Hexamers.	Frontiers in Molecular Biosciences	2021
34079818	An Integrated Computational and Experimental Approach to Identifying Inhibitors for SARS-CoV-2 3CL Protease.	Frontiers in Molecular Biosciences	2021
33755013	Allosteric communication in class A Î²-lactamases occurs via cooperative coupling of loop dynamics.	eLife	2021
34125151	DIAPH1 Variants in Non-East Asian Patients With Sporadic Moyamoya Disease.	JAMA Neurol	2021
34124899	Dynamic Profiling of Î²-Coronavirus 3CL M Protease Ligand-Binding Sites.	Journal of Chemical Information and Modeling	2021
33737712	Suppressor of cytokine signaling-1 mimetic peptides attenuate lymphocyte activation in the MRL/lpr mouse autoimmune model.	Scientific Reports	2021
34319231	Structural basis of the effect of activating mutations on the EGF receptor.	eLife	2021
34023403	Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.	Journal of Molecular Biology	2021
33432185	Author Correction: Mutations disrupting neuritogenesis genes confer risk for cerebral palsy.	Nat Genet	2021
34468536	Nutritional assessment of servicemen in relation to area of duty and feeding habits: a Pakistani prospective.	Brazilian Journal of Biology	2021
34621251	The Role of Hydrophobic Nodes in the Dynamics of Class A Î²-Lactamases.	Frontiers in Microbiology	2021
34720710	Dynamical nonequilibrium molecular dynamics reveals the structural basis for allostery and signal propagation in biomolecular systems.	European Physical Journal B	2021
31541192	Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.	Oncogene	2020
32118142	Electrostatic Switching Controls Channel Dynamics of the Sensor Protein VirB10 in Type IV Secretion System.	ACS Omega	2020
32350300	A Self-Assembling Lipidic Peptide and Selective Partial V2 Receptor Agonist Inhibits Urine Production.	Scientific Reports	2020
31712217	A Standard Numbering Scheme for Class C Î²-Lactamases.	Antimicrob Agents Chemother	2020
32280897	Synergistic Effect of Chlorogenic Acid and Caffeic Acid with Fosfomycin on Growth Inhibition of a Resistant Strain.	ACS Omega	2020
32453431	Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.	Nucleic Acids Research	2020
33262690	Selective Modulation of Î±5 GABA Receptors Exacerbates Aberrant Inhibition at Key Hippocampal Neuronal Circuits in Mouse Model of Alzheimer's Disease.	Frontiers in Cellular Neuroscience	2020
32657326	Structure-based enzyme engineering improves donor-substrate recognition of Arabidopsis thaliana glycosyltransferases.	Biochemical Journal	2020
32989326	Mutations disrupting neuritogenesis genes confer risk for cerebral palsy.	Nat Genet	2020
32879142	Role of in silico structural modeling in predicting immunogenic neoepitopes for cancer vaccine development.	JCI Insight	2020
32650066	In silico drug repositioning of FDA-approved drugs to predict new inhibitors for alpha-synuclein aggregation.		2020
33080032	BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers.	Nucleic Acids Research	2020
32519816	Beyond bone biology: Lessons from team science.	J Orthop Res	2020
33077954	Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.	Nat Med	2020
33127753	First-in-class humanized FSH blocking antibody targets bone and fat.	Proc Natl Acad Sci U S A	2020
32513693	Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass.	Proceedings of the National Academy of Sciences of the United States of America	2020
31460307	Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH Pathway.	ACS Omega	2019
31633931	Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant.	Biochemistry	2019
31627059	Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor.	European Journal of Medicinal Chemistry	2019
31616254	Recessive Inheritance of Congenital Hydrocephalus With Other Structural Brain Abnormalities Caused by Compound Heterozygous Mutations in <i>ATP1A3</i>.	Front Cell Neurosci	2019