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Author Details

Marcel Kool
Hopp Children's Cancer Center (KiTZ)
1990
329
90
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36356895Rare embryonal and sarcomatous central nervous system tumours: State-of-the art and future directions.Eur J Med Genet2023
36356895Rare embryonal and sarcomatous central nervous system tumours: State-of-the art and future directions.Eur J Med Genet2023
37679810Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours.Genome Med2023
37835571The Site of Origin of Medulloblastoma: Surgical Observations Correlated to Molecular Groups.Cancers (Basel)2023
37883081Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial.JAMA Oncol2023
37093271Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.Acta Neuropathol2023
36715306Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than 2 subgroups.Neuro Oncol2023
37277823Group-specific cellular metabolism in Medulloblastoma.J Transl Med2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37020198The potential of PARP as a therapeutic target across pediatric solid malignancies.BMC Cancer2023
37020038Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities.Oncogene2023
36765089Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.Nat Commun2023
36702933Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.Nat Cancer2023
36635768Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses.Acta Neuropathol Commun2023
37450044Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.Acta Neuropathol2023
37441939Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.Eur J Cancer2023
37379234Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.Neuro Oncol2023
37183219Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.J Neurooncol2023
36459208Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.Acta Neuropathol2023
37501103Mitochondrial DNA mutations in Medulloblastoma.Acta Neuropathol Commun2023
36782314CNS tumor with EP300::BCOR fusion: discussing its prevalence in adult population.Acta Neuropathol Commun2023
37835571The Site of Origin of Medulloblastoma: Surgical Observations Correlated to Molecular Groups.Cancers (Basel)2023
37883081Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial.JAMA Oncol2023
37501103Mitochondrial DNA mutations in Medulloblastoma.Acta Neuropathol Commun2023
37679810Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours.Genome Med2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37020198The potential of PARP as a therapeutic target across pediatric solid malignancies.BMC Cancer2023
37020038Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities.Oncogene2023
37450044Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.Acta Neuropathol2023
37183219Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.J Neurooncol2023
37379234Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.Neuro Oncol2023
37277823Group-specific cellular metabolism in Medulloblastoma.J Transl Med2023
37441939Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.Eur J Cancer2023
37093271Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.Acta Neuropathol2023
36782314CNS tumor with EP300::BCOR fusion: discussing its prevalence in adult population.Acta Neuropathol Commun2023
36715306Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than 2 subgroups.Neuro Oncol2023
36765089Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.Nat Commun2023
36635768Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses.Acta Neuropathol Commun2023
36459208Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.Acta Neuropathol2023
36702933Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.Nat Cancer2023
33283872Corrigendum to: Molecular subgrouping of atypical teratoid/rhabdoid tumors-a reinvestigation and current consensus.Neuro Oncol2022
36182817Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program 'iTHER'.Eur J Cancer2022
36180532Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D.Nat Protoc2022
35771282Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression.Acta Neuropathol2022
35446794SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome.Am J Surg Pathol2022
36291912Improved Long-Term Survival of Patients with Recurrent Medulloblastoma Treated with a "MEMMAT-like" Metronomic Antiangiogenic Approach.Cancers (Basel)2022
35831316The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.Nat Commun2022
35501487ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance.Acta Neuropathol2022
36137662Imaging Characteristics of CNS Neuroblastoma-<i>FOXR2</i>: A Retrospective and Multi-Institutional Description of 25 Cases.AJNR Am J Neuroradiol2022
36127323Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.Cell Death Dis2022
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Collaborators

Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 198
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 133
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 110
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 72
Paul A Northcott
St Jude Children's Research Hospital
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Andreas von Deimling
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Peter Lichter
German Cancer Research Center (DKFZ)
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Ulrich Sch??ller
University Medical Center Hamburg-Eppendorf
Co-authored papers 47
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
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Marina Ryzhova
N.N. Burdenko Neurosurgical Institute
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Stefan Rutkowski
University Medical Center Hamburg-Eppendorf
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Till Milde
Hopp Children's Cancer Center Heidelberg (KiTZ)
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Pascal D Johann
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Michael C Frühwald
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Torsten Pietsch
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Dominik Sturm
Hopp Children's Cancer Center Heidelberg (KiTZ)
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Felix Sahm
Hopp Children's Cancer Center Heidelberg (KiTZ)
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Nada Jabado
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 38
Olaf Witt
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 38
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 36
Kristian W Pajtler
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg University
Co-authored papers 36
David Capper
Charite University Medicine Berlin
Co-authored papers 33
Martin Sill
Co-authored papers 31
Hendrik Witt
Co-authored papers 31
Jan Koster
Amsterdam University Medical Centers location AMC
Co-authored papers 30
Katja von Hoff
Co-authored papers 29
David W Ellison
St. Jude Children's Research Hospital
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Natalie J??ger
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Christine Haberler
Co-authored papers 25
Lukas Chavez
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Release 1.2