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Author Details

Samah El Ghamrasni
Princess Margaret Cancer Centre, University Health Network
2010
20
12
PMIDPaper TitleJournal TitlePublished Year
36736318IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.Cancer Cell2023
37697435RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.Nucleic Acids Res2023
37987734Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality.Cancer Res2023
34556523Mutations in Noncoding <i>Cis</i>-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer.Mol Cancer Res2022
36108220Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.Cancer Discov2022
36070391The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER<sup>+</sup> breast cancer with mitotic aberrations.Sci Adv2022
35896551Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.Nat Commun2022
34234122Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.Nat Commun2021
33529165RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.J Clin Invest2021
34446728Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.Nat Commun2021
32345369Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor.Genome Med2020
27558965RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.Nat Commun2016
24858046Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.Oncogene2015
23382699Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.PLoS Genet2013
24324146RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.Proc Natl Acad Sci U S A2013
23681708Systemic ceramide accumulation leads to severe and varied pathological consequences.EMBO Mol Med2013
22343728Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis.Blood2012
21625617Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.PLoS Genet2011
20385750Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer.J Exp Med2010
20696928Dysregulation of the mevalonate pathway promotes transformation.Proc Natl Acad Sci U S A2010
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Collaborators

Razqallah Hakem
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 11
Anne Hakem
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 10
Jeff P Bruce
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Otto Sanchez
Ontario Tech University
Co-authored papers 5
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
David W Cescon
Princess Margaret Cancer Centre
Co-authored papers 4
Robert G Bristow
University of Toronto
Co-authored papers 3
Parasvi S Patel
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Benjamin Haibe-Kains
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Hal K Berman
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Kevin Y Yip
Co-authored papers 2
Stephenie D Prokopec
University Health Network
Co-authored papers 2
Jennifer Cruickshank
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers 2
Linda Z Penn
University of Toronto
Co-authored papers 2
Andrew J Elia
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 2
Fei-Fei Liu
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
Andrea Jurisicova
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 2
Jeffrey L Wrana
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 1
Philippe L Bedard
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Anna Martirosyan
West Virginia University
Co-authored papers 1
Minggao Liang
University of Toronto
Co-authored papers 1
Fereshteh Khosravi
b Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Cherry Have
University Health Network
Co-authored papers 1
James R Hawley
Princess Margaret Cancer Research Centre
Co-authored papers 1
Daniel Durocher
The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 1
Susan J Done
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Paul C Boutros
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