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Author Details

Florentine S Hilbers
Netherlands Cancer Institute
2012
34
17
PMIDPaper TitleJournal TitlePublished Year
38059899Pregnancy After Breast Cancer in Young BRCA Carriers: An International Hospital-Based Cohort Study.JAMA2024
37689749High-dose alkylating chemotherapy in BRCA-altered triple-negative breast cancer: the randomized phase III NeoTN trial.NPJ Breast Cancer2023
34625860Correction to: Tolerability and toxicity of trastuzumab or trastuzumabâ¿¿+â¿¿lapatinib in older patients: a subâ¿¿analysis of the ALTTO trial (BIG 2â¿¿06; NCCTG (Alliance) N063D).Breast Cancer Res Treat2022
35587322Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature.Breast Cancer Res Treat2022
35610260Adaptive immune signature in HER2-positive breast cancer in NCCTG (Alliance) N9831 and NeoALTTO trials.NPJ Breast Cancer2022
36126477Ten-year follow-up of the observational RASTER study, prospective evaluation of the 70-gene signature in ER-positive, HER2-negative, node-negative, early breast cancer.Eur J Cancer2022
33787900Tumor Cellularity and Infiltrating Lymphocytes as a Survival Surrogate in HER2-Positive Breast Cancer.J Natl Cancer Inst2022
35172272Serum thymidine kinase activity in patients with hormone receptor-positive and HER2-negative metastatic breast cancer treated with palbociclib and fulvestrant.Eur J Cancer2022
32951084Tolerability and toxicity of trastuzumab or trastuzumabâ¿¿+â¿¿lapatinib in older patients: a sub-analysis of the ALTTO trial (BIG 2-06; NCCTG (Alliance) N063D).Breast Cancer Res Treat2021
3372156170-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age.Lancet Oncol2021
34183353Genomic and Transcriptomic Analyses of Breast Cancer Primaries and Matched Metastases in AURORA, the Breast International Group (BIG) Molecular Screening Initiative.Cancer Discov2021
34312396Evaluation of multiple transcriptomic gene risk signatures in male breast cancer.NPJ Breast Cancer2021
33401235Body Mass Index and Weight Change in Patients With HER2-Positive Early Breast Cancer: Exploratory Analysis of the ALTTO BIG 2-06 Trial.J Natl Compr Canc Netw2021
32203207Long-term cardiac outcomes of patients with HER2-positive breast cancer treated in the adjuvant lapatinib and/or trastuzumab Treatment Optimization Trial.Br J Cancer2020
32085669Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy.Int J Mol Sci2020
32083990Standard Anthracycline Based Versus Docetaxel-Capecitabine in Early High Clinical and/or Genomic Risk Breast Cancer in the EORTC 10041/BIG 3-04 MINDACT Phase III Trial.J Clin Oncol2020
33052755Road Map to Safe and Well-Designed De-escalation Trials of Systemic Adjuvant Therapy for Solid Tumors.J Clin Oncol2020
33154022Prognostic role of distant disease-free interval from completion of adjuvant trastuzumab in HER2-positive early breast cancer: analysis from the ALTTO (BIG 2-06) trial.ESMO Open2020
32422170Expanding the landscape of actionable genomic alterations in metastatic breast cancer: comprehensive genomic profiling for all?Ann Oncol2020
32383162Clustering of known low and moderate risk alleles rather than a novel recessive high-risk gene in non-BRCA1/2 sib trios affected with breast cancer.Int J Cancer2020
30335191Pregnancies during and after trastuzumab and/or lapatinib in patients with human epidermal growth factor receptor 2-positive early breast cancer: Analysis from the NeoALTTO (BIG 1-06) and ALTTO (BIG 2-06) trials.Cancer2019
31853266An RB-1 loss of function gene signature as a tool to predict response to neoadjuvant chemotherapy plus anti-HER2 agents: a substudy of the NeoALTTO trial (BIG 1-06).Ther Adv Med Oncol2019
31186341Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-<i>BRCA1/2</i> breast cancer families.J Med Genet2019
30814109Plasma miRNA Levels for Predicting Therapeutic Response to Neoadjuvant Treatment in HER2-positive Breast Cancer: Results from the NeoALTTO Trial.Clin Cancer Res2019
31134488Dissecting the effect of hormone receptor status in patients with HER2-positive early breast cancer: exploratory analysis from the ALTTO (BIG 2-06) randomized clinical trial.Breast Cancer Res Treat2019
27233470Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility Gene XRCC2.Hum Mutat2016
26130695FANCM c.5791C&gt;T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor.Hum Mol Genet2015
23383274Exome sequencing of germline DNA from non-BRCA1/2 familial breast cancer cases selected on the basis of aCGH tumor profiling.PLoS One2013
24025038The impact of next generation sequencing on the analysis of breast cancer susceptibility: a role for extremely rare genetic variation?Clin Genet2013
23809231COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration.Breast Cancer Res2013
23409019Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles.PLoS One2013
22100658Genetic variants in TGFβ-1 and PAI-1 as possible risk factors for cardiovascular disease after radiotherapy for breast cancer.Radiother Oncol2012
22464251Rare mutations in XRCC2 increase the risk of breast cancer.Am J Hum Genet2012
23054243Rare variants in XRCC2 as breast cancer susceptibility alleles.J Med Genet2012
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Konstantinos Tryfonidis
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Kim Benstead
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Judith Fraser
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Esther M John
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Larry Norton
Memorial Sloan Kettering Cancer Center
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