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Author Details

Jeffrey R Shearstone
Syros Pharmaceuticals
1999
19
15
PMIDPaper TitleJournal TitlePublished Year
37316562Erythroid lineage chromatin accessibility maps facilitate identification and validation of NFIX as a fetal hemoglobin repressor.Commun Biol2023
28579617HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.Leukemia2018
28060870Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.PLoS One2017
27073918Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2.PLoS One2016
25605023HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma.Oncotarget2015
22308039Integrin β4 regulates SPARC protein to promote invasion.J Biol Chem2012
23213459Effects of β4 integrin expression on microRNA patterns in breast cancer.Biol Open2012
21847081Identification and analysis of mouse erythroid progenitors using the CD71/TER119 flow-cytometric assay.J Vis Exp2011
22076376Global DNA demethylation during mouse erythropoiesis in vivo.Science2011
19911006AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.Cell Death Differ2010
20877475A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression.PLoS Biol2010
19109961TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis.Gastroenterology2009
16624518Accurate and precise transcriptional profiles from 50 pg of total RNA or 100 flow-sorted primary lymphocytes.Genomics2006
16823376A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies.Nat Biotechnol2006
16736506Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts.Arthritis Rheum2006
16947635Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.Arthritis Rheum2006
15718098Application of functional genomic technologies in a mouse model of retinal degeneration.Genomics2005
12019778Nondestructive quality control for microarray production.Biotechniques2002
10187768Biochemical characterization of the small heat shock protein IbpB from Escherichia coli.J Biol Chem1999
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Collaborators

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Center for Computational and Integrative Biology, Massachusetts General Hospital
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Harvard Medical School
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University of Washington School of Medicine
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Norwegian University of Science and Technology
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Kirk Kerkorian School of Medicine of University of Nevada
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University of Washington
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University of Maine
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Howard Hughes Medical Institute, Harvard Medical School
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University of Massachusetts Medical School
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Institute for Cancer Research, Norwegian Radium Hospital
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Harvard School of Dental Medicine
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CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
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