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Author Details
Full Name
Jeffrey R Shearstone
Affiliation
Syros Pharmaceuticals
ORCID
Career Start Year
1999
Papers
19
H Index
15
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37316562
Erythroid lineage chromatin accessibility maps facilitate identification and validation of NFIX as a fetal hemoglobin repressor.
Commun Biol
2023
28579617
HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.
Leukemia
2018
28060870
Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.
PLoS One
2017
27073918
Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2.
PLoS One
2016
25605023
HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma.
Oncotarget
2015
22308039
Integrin β4 regulates SPARC protein to promote invasion.
J Biol Chem
2012
23213459
Effects of β4 integrin expression on microRNA patterns in breast cancer.
Biol Open
2012
21847081
Identification and analysis of mouse erythroid progenitors using the CD71/TER119 flow-cytometric assay.
J Vis Exp
2011
22076376
Global DNA demethylation during mouse erythropoiesis in vivo.
Science
2011
19911006
AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Cell Death Differ
2010
20877475
A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression.
PLoS Biol
2010
19109961
TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis.
Gastroenterology
2009
16624518
Accurate and precise transcriptional profiles from 50 pg of total RNA or 100 flow-sorted primary lymphocytes.
Genomics
2006
16823376
A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies.
Nat Biotechnol
2006
16736506
Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts.
Arthritis Rheum
2006
16947635
Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
Arthritis Rheum
2006
15718098
Application of functional genomic technologies in a mouse model of retinal degeneration.
Genomics
2005
12019778
Nondestructive quality control for microarray production.
Biotechniques
2002
10187768
Biochemical characterization of the small heat shock protein IbpB from Escherichia coli.
J Biol Chem
1999
1 - 19 of 19
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