Author details

Full Name

Yaroslav Tsybovsky

Affiliation

ORCID

Career Start Year

2000

Papers

113

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37098956	Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.		2023
36411391	A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.	Nat Chem Biol	2023
37766115	Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes.	Vaccines (Basel)	2023
37738240	Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus.	PLoS Pathog	2023
38096058	Antigen spacing on protein nanoparticles influences antibody responses to vaccination.		2023
37794071	Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera.	Nat Commun	2023
37553406	Self-assembling SARS-CoV-2 spike-HBsAg nanoparticles elicit potent and durable neutralizing antibody responses via genetic delivery.	NPJ Vaccines	2023
36906406	Characterization of Flu MOSAIC nanoparticle vaccine candidate using high performance size-exclusion chromatography to support vaccine process development.		2023
37436899	HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.	Cell Rep	2023
36932063	Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.		2023
37428933	Increased neutralization potency and breadth elicited by a SARS-CoV-2 mRNA vaccine forming virus-like particles.		2023
37295404	Vaccine elicitation and structural basis for antibody protection against alphaviruses.	Cell	2023
37292995	Antigen spacing on protein nanoparticles influences antibody responses to vaccination.		2023
35324257	Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.	Science	2022
36306784	Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.	Immunity	2022
35841885	Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.	Structure	2022
35709309	Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4.	PLoS Pathogens	2022
36302375	Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants.	Cell Reports	2022
36356572	Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.	Immunity	2022
35383176	Structure-based design of stabilized recombinant influenza neuraminidase tetramers.	Nat Commun	2022
36344847	Cryo-EM structures of prefusion SIV envelope trimer.	Nat Struct Mol Biol	2022
35677079	Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins.	bioRxiv	2022
35609088	Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron.	PLoS ONE	2022
35982676	Breathing and tilting: mesoscale simulations illuminate influenza glycoprotein vulnerabilities.	bioRxiv	2022
36380759	Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups.	Res Sq	2022
36589893	Breathing and Tilting: Mesoscale Simulations Illuminate Influenza Glycoprotein Vulnerabilities.	ACS Cent Sci	2022
35319830	Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2.	Advanced Science	2022
35013550	Structure of putative tumor suppressor ALDH1L1.	Communications Biology	2022
34587480	Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.	Cell Rep	2021
34020817	A non-affinity purification process for GMP production of prefusion-closed HIV-1 envelope trimers from clades A and C for clinical evaluation.	Vaccine	2021
33803622	Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria.	Vaccines	2021
33741916	A comprehensive influenza reporter virus panel for high-throughput deep profiling of neutralizing antibodies.	Nature Communications	2021
33688659	Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants.	bioRxiv	2021
34210892	Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.	Science	2021
34098567	Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.	Nature	2021
33826898	Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base.	Cell Reports	2021
33655252	Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.	bioRxiv	2021
33442681	Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.	bioRxiv	2021
34244481	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.	Nature Communications	2021
33494381	Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses.	Vaccines (Basel)	2021
34679128	Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens.	PLoS Pathogens	2021
34461095	SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.	J Biol Chem	2021
34551978	Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.	Proceedings of the National Academy of Sciences of the United States of America	2021
35018379	Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron.		2021
34956199	Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine.	Frontiers in Immunology	2021
34887575	A multiclade env-gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques.	Nature Medicine	2021
33271067	Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.	Cell Host Microbe	2020
32295908	Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.	Journal of Virology	2020
32034141	Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses.	Nature Communications	2020
33318483	Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.	NPJ Vaccines	2020