Author details

Full Name

Benjamin H Kwok

Affiliation

Institute for Research in Immunology and Cancer, Universite de Montreal

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

Sami Nourreddine (CM4AI)

PMID	Paper Title	Journal Title	Published Year
34131133	Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.	Nat Commun	2021
34848715	Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.	Nat Commun	2021
32665245	BMP signaling is essential for sustaining proximo-distal progression in regenerating axolotl limbs.	Development	2020
31951198	Kinesin Kif2C in regulation of DNA double strand break dynamics and repair.	Elife	2020
31919497	Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny.	Hum Mol Genet	2020
30388224	Loss-of-function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish.	Hum Mol Genet	2019
31712417	Structural studies of the eIF4E-VPg complex reveal a direct competition for capped RNA: Implications for translation.	Proc Natl Acad Sci U S A	2019
29980677	Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.	Nat Commun	2018
28944456	DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases.	FEBS Lett	2017
28147230	Multimodal and Polymorphic Interactions between Anillin and Actin: Their Implications for Cytokinesis.	J Mol Biol	2017
27829147	Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells.	Cell Rep	2016
26609108	Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer.	Mol Cancer Res	2016
27797342	High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.	J Clin Invest	2016
25807524	GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.	Sci Rep	2015
24859087	DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases.	FEBS Lett	2014
25332165	Interdomain allosteric regulation of Polo kinase by Aurora B and Map205 is required for cytokinesis.	J Cell Biol	2014
25135640	Structural maintenance of chromosome (SMC) proteins link microtubule stability to genome integrity.	J Biol Chem	2014
24949858	KIF14 binds tightly to microtubules and adopts a rigor-like conformation.	J Mol Biol	2014
23857773	The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex.	J Cell Biol	2013
22949619	An inwardly rectifying K+ channel is required for patterning.	Development	2012
18321079	Efficient identification of phosphorylation by mass spectrometric phosphopeptide fingerprinting.	Anal Chem	2008
18678707	Microtubule cross-linking triggers the directional motility of kinesin-5.	J Cell Biol	2008
17174541	Microtubule flux: drivers wanted.	Curr Opin Cell Biol	2007
16892050	Allosteric inhibition of kinesin-5 modulates its processive directional motility.	Nat Chem Biol	2006
17028580	Probing cell-division phenotype space and Polo-like kinase function using small molecules.	Nat Chem Biol	2006
15875026	The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.	Nature	2005
15149232	Total synthesis of TMC-95A and -B via a new reaction leading to Z-enamides. Some preliminary findings as to SAR.	J Am Chem Soc	2004
15458652	The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5.	Curr Biol	2004
12794861	Simplified synthetic TMC-95A/B analogues retain the potency of proteasome inhibitory activity.	Chembiochem	2003
14521833	Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm.	Curr Biol	2003
12056916	Characterization of a novel mammalian phosphatase having sequence similarity to Schizosaccharomyces pombe PHO2 and Saccharomyces cerevisiae PHO13.	Biochemistry	2002
11514225	The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase.	Chem Biol	2001
10465562	Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology.	Bioorg Med Chem Lett	1999
10468620	Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity.	Proc Natl Acad Sci U S A	1999
10383134	Eponemycin exerts its antitumor effect through the inhibition of proteasome function.	Cancer Res	1999

1 - 35 of 35

Florent Dingli

Institut Curie, PSL Research University

Career Start Year 2011

Number of shared co-authors 0

Neil T Umbreit

University of Washington

Career Start Year 2010

Number of shared co-authors 0

B??rang??re Lombard

Institut Curie, PSL Research University

Career Start Year 2005

Number of shared co-authors 0

Jay R Unruh

Stowers Institute for Medical Research

Career Start Year 2003

Number of shared co-authors 1

Ge Yang

College of Chemistry, Sichuan University

Career Start Year 2003

Number of shared co-authors 1

Alex Zelter

University of Washington

Career Start Year 2003

Number of shared co-authors 0

Gary J Brouhard

McGill University

Career Start Year 2003

Number of shared co-authors 0

Won-Jing Wang

Institute of Biochemistry and Molecular Biology, National Yang Ming University

Career Start Year 2002

Number of shared co-authors 0

Yusuke Toyoda

Institute of Life Science, Kurume University

Career Start Year 2002

Number of shared co-authors 0

Ina Poser

Max Planck Institute of Molecular Cell Biology and Genetics

Career Start Year 2001

Number of shared co-authors 0

Andrew P VanDemark

University of Pittsburgh

Career Start Year 2000

Number of shared co-authors 0

Rachel Toth

University of Dundee

Career Start Year 1999

Number of shared co-authors 0

Daniel W Gerlich

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)

Career Start Year 1998

Number of shared co-authors 1

Torsten Wittmann

University of California san francisco

Career Start Year 1997

Number of shared co-authors 0

Damarys Loew

Institut Curie, PSL Research University

Career Start Year 1996

Number of shared co-authors 0

Ram Dixit

MedStar Health National Center for Human Factors in Healthcare

Career Start Year 1995

Number of shared co-authors 0

Luke M Rice

the University of Texas Southwestern Medical Center

Career Start Year 1994

Number of shared co-authors 0

Jean-Karim H??rich??

University of California san francisco

Career Start Year 1994

Number of shared co-authors 0

Yannick Gachet

Universite de Toulouse, CNRS

Career Start Year 1993

Number of shared co-authors 0

Nico Stuurman

University of California san francisco

Career Start Year 1989

Number of shared co-authors 0

Matthias Peter

Institute of Biochemistry, ETH Zurich

Career Start Year 1989

Number of shared co-authors 1

Peter K Jackson

Stanford University School of Medicine, Center for Clinical Sciences Research

Career Start Year 1989

Number of shared co-authors 1

Stefan Knapp

Institute of Pharmaceutical Chemistry, Goethe University

Career Start Year 1983

Number of shared co-authors 0

Ashok R Venkitaraman

University of Cambridge, Hutchison Research Centre

Career Start Year 1982

Number of shared co-authors 0

Stephen J Elledge

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School

Career Start Year 1982

Number of shared co-authors 1

Trisha N Davis

University of Washington

Career Start Year 1982

Number of shared co-authors 0

Thomas S Hays

University of Minnesota

Career Start Year 1982

Number of shared co-authors 0

J. Wade Harper

Harvard Medical School

Career Start Year 1981

Number of shared co-authors 1

Lawrence S B Goldstein

university of california san diego

Career Start Year 1975

Number of shared co-authors 0

Anthony A Hyman

Max Planck Institute of Molecular Cell Biology and Genetics

Career Start Year 1971

Number of shared co-authors 0

row(s) 1 - 30 of 30

S??bastien Carreno

Institute for Research in Immunology and Cancer, Universite de Montreal

Co-authored papers 4

Khaled Ben El Kadhi

New York University

Co-authored papers 4

Michael A Koldobskiy

Co-authored papers 2

Mathieu Tremblay

Universite de Montreal, Institute for Research in Immunology and Cancer

Co-authored papers 1

Iman Fares

Dana-Farber Cancer Institute

Co-authored papers 1

Veronique Litalien

Walter and Eliza Hall Institute of Medical Research

Co-authored papers 1

Bastien Gerby

Universite de Toulouse, Inserm, Universite Toulouse III-Paul Sabatier

Co-authored papers 1

Young-Goo Han

St. Jude Children's Research Hospital

Co-authored papers 1

Guy Sauvageau

Universite de Montreal

Co-authored papers 1

Cristina Risi

Eastern Virginia Medical School

Co-authored papers 1

Brian T Chait

The Rockefeller University

Co-authored papers 1

Diogo F T Veiga

University of Campinas (UNICAMP)

Co-authored papers 1

Genevi??ve Lavoie

Institute for Research in Immunology and Cancer (IRIC)

Co-authored papers 1

Marie-Jos??e H??bert

Universite de Montreal

Co-authored papers 1

Vitold E Galkin

Eastern Virginia Medical School

Co-authored papers 1

Milena Kosic

Leslie Dan Faculty of Pharmacy and Department of Biochemistry, University of Toronto

Co-authored papers 1

Sami Nourreddine (CM4AI)

University of California San Diego

Co-authored papers 1

Rachel H Giles

University Medical Center Utrecht

Co-authored papers 1

Julianne Ouellette

Co-authored papers 1

David Feny??

Institute for Systems Genetics, NYU Grossman School of Medicine

Co-authored papers 1

Elizabeth Ottoni

Universite de Montreal

Co-authored papers 1

Trang Hoang

Department of Biomedical Science and Center for Bio-Nanomaterials, Daegu University

Co-authored papers 1

Joel Ryan

McGill University

Co-authored papers 1

Dominique Geoffrion

Centre hospitalier universitaire de l'Universite de Montreal (CHUM)

Co-authored papers 1

Anne Marinier

Institute for Research in Immunology and Cancer

Co-authored papers 1

Philippe P Roux

IRIC - University of Montreal

Co-authored papers 1

Jana Krosl

The Leucegene Project at Institute for Research in Immunology and Cancer.

Co-authored papers 1

Andr?? Haman

Universite de Montreal, Institute for Research in Immunology and Cancer

Co-authored papers 1

Jalila Chagraoui

Institute for Research in Immunology and Cancer, University of Montreal

Co-authored papers 1

Paul S Maddox

University of North Carolina at Chapel Hill

Co-authored papers 1

1 - 30

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