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Author Details

Patricia Pearl O'Rourke
Harvard Medical School
1982
61
24
PMIDPaper TitleJournal TitlePublished Year
34998990Responding to signals of mental and behavioral health risk in pragmatic clinical trials: Ethical obligations in a healthcare ecosystem.Contemp Clin Trials2022
36484509Clarifying the Ethics and Oversight of Chimeric Research.Hastings Cent Rep2022
32342753Expert Perspectives on Oversight for Unregulated mHealth Research: Empirical Data and Commentary.J Law Med Ethics2020
30008546Pragmatic Tools for Sharing Genomic Research Results with the Relatives of Living and Deceased Research Participants.J Law Med Ethics2018
28661755The Final Rule: When the Rubber Meets the Road.Am J Bioeth2017
27294961Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research.J Pers Med2016
25406606Central institutional review board review for an academic trial network.Acad Med2015
26479560Canadian Research Ethics Board Leadership Attitudes to the Return of Genetic Research Results to Individuals and Their Families.J Law Med Ethics2015
26479559Return of Genetic Research Results to Participants and Families: IRB Perspectives and Roles.J Law Med Ethics2015
26479555Returning a Research Participant's Genomic Results to Relatives: Analysis and Recommendations.J Law Med Ethics2015
26374678Harmonization and streamlining of research oversight for pragmatic clinical trials.Clin Trials2015
26041702Global implementation of genomic medicine: We are not alone.Sci Transl Med2015
24763287Framework for development of physician competencies in genomic medicine: report of the Competencies Working Group of the Inter-Society Coordinating Committee for Physician Education in Genomics.Genet Med2014
22935716Return of research results from genomic biobanks: cost matters.Genet Med2013
23872832Genomic medicine: too great expectations?Clin Pharmacol Ther2013
23738513The OHRP and SUPPORT.N Engl J Med2013
23386185Return of research results from genomic biobanks: a call for data.Genet Med2013
22881849Part-human animal research: the imperative to move beyond a philosophical debate.Am J Bioeth2012
21156933Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group.Circ Cardiovasc Genet2010
21131720Mainstreaming animal-assisted therapy.ILAR J2010
18397750Centralized banks for human embryonic stem cells: a worthwhile challenge.Cell Stem Cell2008
17710705An immodest proposal: banking embryonic stem cells for solid organ transplantation is problematic and premature.Am J Bioeth2007
16769458The Bartlett et al extracorporeal membrane oxygenation case series from 1977, with expert commentary provided by Dr P. Pearl O'Rourke.J Crit Care2006
11269465Effect of extracorporeal membrane oxygenation on left ventricular function of swine.Ann Thorac Surg2001
11269466Left ventricular dysfunction during extracorporeal membrane oxygenation in a hypoxemic swine model.Ann Thorac Surg2001
10757192Nonpulmonary organ failure and outcome in children treated with high-frequency oscillatory ventilation.J Crit Care2000
10834717Attitudes toward limitation of support in a pediatric intensive care unit.Crit Care Med2000
10446832Clinical uses and controversies of neuromuscular blocking agents in infants and children.Crit Care Med1999
9034268High-frequency oscillatory ventilation with partial liquid ventilation in a model of acute respiratory failure.Crit Care Med1997
9034277Morphine pharmacokinetics during continuous infusion of morphine sulfate for infants receiving extracorporeal membrane oxygenation.Crit Care Med1997
7858689A prospective study of femoral catheter-related thrombosis in children.Arch Pediatr Adolesc Med1995
8547564High-frequency oscillatory ventilation in the management of infants with pulmonary hemorrhage after cardiac surgery.J Cardiothorac Vasc Anesth1995
7785266Cardiac rhabdomyoma with cardiac arrest.West J Med1995
8365238Congenital diaphragmatic hernia: are there reliable clinical predictors?Crit Care Med1993
8516067Bronchiolitis obliterans: a complication of group B streptococcal disease treated with extracorporeal membrane oxygenation.Pediatrics1993
8483064Extracorporeal membrane oxygenation: support for overwhelming pulmonary failure in the pediatric population. Collective experience from the extracorporeal life support organization.J Pediatr Surg1993
8308230Spontaneous pneumomediastinum.J Emerg Med1993
8374648Drowning and immersion injuries in children.Curr Opin Pediatr1993
8239341Repair of a laryngotracheoesophageal cleft in an infant by means of extracorporeal membrane oxygenation.Ann Otol Rhinol Laryngol1993
1443693Extracorporeal membrane oxygenation.Anesth Analg1992
1501013Delayed repair and preoperative ECMO does not improve survival in high-risk congenital diaphragmatic hernia.J Pediatr Surg1992
1521432Use of extracorporeal life support in patients with congenital heart disease: state of the art?Crit Care Med1992
1956735Cardiotoxicity during treatment of severe childhood asthma.Pediatrics1991
10145498ECMO: where have we been? Where are we going?Respir Care1991
2023071The effect of extracorporeal membrane oxygenation on the survival of neonates with high-risk congenital diaphragmatic hernia: 45 cases from a single institution.J Pediatr Surg1991
1934407Extracorporeal life support for cardiac assist in pediatric patients. Review of ELSO Registry data.Circulation1991
2308029Pediatric applications of extracorporeal membrane oxygenation.J Pediatr1990
10145335Complications of mechanical ventilation in a children's hospital multidisciplinary intensive care unit.Respir Care1990
2395598Oxygen extraction in lamb skeletal muscle.Pediatr Res1990
2811427Role of extracorporeal membrane oxygenation in selected pediatric respiratory problems.J Thorac Cardiovasc Surg1989
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Collaborators

Center for Biomedical Ethics and Society, Vanderbilt University Medical Center
Co-authored papers 6
Boston Children's Hospital
Co-authored papers 6
University of Utah School of Medicine
Co-authored papers 6
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 4
University of Washington School of Medicine.
Co-authored papers 4
Patient-Centered Outcomes Research Institute
Co-authored papers 3
Law School and Medical School, University of Minnesota
Co-authored papers 3
Baylor College of Medicine.
Co-authored papers 3
The Heart Institute, Cincinnati Children's Hospital Medical Center
Co-authored papers 2
University of Washington
Co-authored papers 2
University of Minnesota
Co-authored papers 2
University of Louisville
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Mt Sinai School of Medicine
Co-authored papers 2
University of California-San Francisco.
Co-authored papers 2
University of Minnesota
Co-authored papers 2
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
Co-authored papers 2
Queensland University of Technology
Co-authored papers 2
Seattle Children's Hospital, University of Washington School of Medicine
Co-authored papers 2
University of Washington
Co-authored papers 2
Departments of Pharmaceutical Sciences.
Co-authored papers 2
University of Alabama at Birmingham
Co-authored papers 2
University of Maryland School of Medicine
Co-authored papers 2
University of Michigan, 1150 West Medical Center Dr. MSRB II ann arbor
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Johns Hopkins University, Berman Institute of Bioethics
Co-authored papers 2
University of Minnesota
Co-authored papers 2
Biomedical Ethics, Mayo Clinic and Foundation
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
George Washington University School of Medicine and Health Sciences
Co-authored papers 2