Author details

Full Name

Ingrid Meulenbelt

Affiliation

ORCID

Career Start Year

1991

Papers

172

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37525432	Mechanical stress and inflammation have opposite effects on Wnt signaling in human chondrocytes.		2023
35532170	Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants.	Rheumatology (Oxford)	2023
36040165	Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis.	Rheumatology (Oxford)	2023
36208715	WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes.	Osteoarthritis and Cartilage	2023
36546648	CCN4/WISP1 Promotes Migration of Human Primary Osteoarthritic Chondrocytes.		2023
36927643	Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis.		2023
35088088	A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis.	Human Molecular Genetics	2022
35383365	Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.	Rheumatology (Oxford)	2022
35679866	An epigenome-wide view of osteoarthritis in primary tissues.	Am J Hum Genet	2022
35412619	Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization.	Rheumatology (Oxford)	2022
36056373	Characterizing the secretome of licensed hiPSC-derived MSCs.	Stem Cell Res Ther	2022
36474468	A human 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress.		2022
33989379	The role of TNFRSF11B in development of osteoarthritic cartilage.	Rheumatology	2022
34730803	Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis.	Rheumatology (Oxford)	2022
35227892	ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease.	Osteoarthritis and Cartilage	2022
34600121	How does hip osteoarthritis differ from knee osteoarthritis?	Osteoarthritis and Cartilage	2022
34412027	Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis.	Ann Rheum Dis	2021
37117594	Censoring exosomal crosstalk in osteoarthritis.		2021
34241697	Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells.	Cell Tissue Res	2021
34260695	Clock genes for joint health: if we could turn back time.	Rheumatology	2021
33608843	Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis.	Rheumatology and Therapy	2021
33984465	Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin.	Osteoarthritis and Cartilage	2021
34357595	Cripto favors chondrocyte hypertrophy via TGF-Î² SMAD1/5 signaling during development of osteoarthritis.	Journal of Pathology	2021
32885253	Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.	Rheumatology (Oxford)	2021
33258547	RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.	Arthritis Rheumatol	2021
32896247	Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls.	Clinical and Experimental Rheumatology	2021
33055079	Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify <i>WNT9A</i> as novel osteoarthritis gene.	Ann Rheum Dis	2021
34572569	Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility-Towards Identification of Applicable Early OA Biomarkers.	Biomolecules	2021
34739320	High-impact mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II.	Science advances	2021
34399844	Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.	Arthritis Res Ther	2021
32840049	Elucidating Epigenetic Regulation by Identifying Functional cis-Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage.	Arthritis Rheumatol	2020
32767602	The miRNA-mRNA interactome of murine induced pluripotent stem cell-derived chondrocytes in response to inflammatory cytokines.	FASEB Journal	2020
30649473	Increased WISP1 expression in human osteoarthritic articular cartilage is epigenetically regulated and decreases cartilage matrix production.	Rheumatology	2019
30504444	RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.	Ann Rheum Dis	2019
30298554	Annotating Transcriptional Effects of Genetic Variants in Disease-Relevant Tissue: Transcriptome-Wide Allelic Imbalance in Osteoarthritic Cartilage.	Arthritis Rheumatol	2019
29800616	Osteoarthritis as a disease of the cartilage pericellular matrix.	Matrix Biology	2018
30209244	ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone.	Science Translational Medicine	2018
30388399	Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.	Am J Hum Genet	2018
30367059	Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.	Nat Commun	2018
29253246	Validity, reliability, responsiveness and feasibility of four hand mobility measures in hand osteoarthritis.	Rheumatology	2018
27974301	Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis.	Annals of the Rheumatic Diseases	2017
28855172	Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.	Ann Rheum Dis	2017
28827734	Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.	Sci Rep	2017
30509410	Involvement of epigenetics in osteoarthritis.	Best Practice and Research in Clinical Rheumatology	2017
27028588	The first international workshop on the epigenetics of osteoarthritis.	Connect Tissue Res	2017
27749371	The role of epigenetics in osteoarthritis: current perspective.	Current Opinion in Rheumatology	2017
27701424	Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.	PLoS Genet	2016
25550340	The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress.	Annals of the Rheumatic Diseases	2016
26833098	Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.	Nat Commun	2016
27134727	Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis.	F1000Res	2016