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Author Details

Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
1997
79
39
PMIDPaper TitleJournal TitlePublished Year
37147424NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia.Leukemia2023
37147424NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia.Leukemia2023
35920299Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context.FASEB J2022
36195275Advances in the development of chordoma models for drug discovery and precision medicine.Biochim Biophys Acta Rev Cancer2022
35920299Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context.FASEB J2022
36195275Advances in the development of chordoma models for drug discovery and precision medicine.Biochim Biophys Acta Rev Cancer2022
34321240Mutant <i>Idh2</i> Cooperates with a <i>NUP98-HOXD13</i> Fusion to Induce Early Immature Thymocyte Precursor ALL.Cancer Res2021
34321240Mutant <i>Idh2</i> Cooperates with a <i>NUP98-HOXD13</i> Fusion to Induce Early Immature Thymocyte Precursor ALL.Cancer Res2021
32111629Deposition of Centromeric Histone H3 Variant CENP-A/Cse4 into Chromatin Is Facilitated by Its C-Terminal Sumoylation.Genetics2020
32111629Deposition of Centromeric Histone H3 Variant CENP-A/Cse4 into Chromatin Is Facilitated by Its C-Terminal Sumoylation.Genetics2020
32032354Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast.PLoS Genet2020
32706863Distinct DNA Methylation Signatures in Neuroendocrine Tumors Specific for Primary Site and Inherited Predisposition.J Clin Endocrinol Metab2020
32819572Cathepsin K is a potent disaggregase of α-synuclein fibrils.Biochem Biophys Res Commun2020
33112233A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells.Elife2020
32839292Genome-Wide Analysis of the FOXA1 Transcriptional Network Identifies Novel Protein-Coding and Long Noncoding RNA Targets in Colorectal Cancer Cells.Mol Cell Biol2020
32999459Repeat expansions confer WRN dependence in microsatellite-unstable cancers.Nature2020
32032354Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast.PLoS Genet2020
33112233A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells.Elife2020
32999459Repeat expansions confer WRN dependence in microsatellite-unstable cancers.Nature2020
32706863Distinct DNA Methylation Signatures in Neuroendocrine Tumors Specific for Primary Site and Inherited Predisposition.J Clin Endocrinol Metab2020
32819572Cathepsin K is a potent disaggregase of α-synuclein fibrils.Biochem Biophys Res Commun2020
32839292Genome-Wide Analysis of the FOXA1 Transcriptional Network Identifies Novel Protein-Coding and Long Noncoding RNA Targets in Colorectal Cancer Cells.Mol Cell Biol2020
30565669Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.Int J Cancer2019
31748606Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice.Sci Rep2019
31622281A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.JCI Insight2019
30565669Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.Int J Cancer2019
31511320HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction.RNA2019
30872698Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells.Sci Rep2019
30992267Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.Blood2019
31748606Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice.Sci Rep2019
31622281A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.JCI Insight2019
31511320HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction.RNA2019
30992267Engineered Bcor mutations lead to acute leukemia of progenitor B-1 lymphocyte origin in a sensitized background.Blood2019
30872698Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells.Sci Rep2019
29191831Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy.J Biol Chem2018
29632643Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient.Oncotarget2018
29191831Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy.J Biol Chem2018
29632643Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient.Oncotarget2018
29296821Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways.Blood Adv2017
29296821Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways.Blood Adv2017
28196408Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.Genes Chromosomes Cancer2017
28196408Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.Genes Chromosomes Cancer2017
27087319Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.Am J Hum Genet2016
27132513TNF-α modulates genome-wide redistribution of οNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.Oncogene2016
27087319Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.Am J Hum Genet2016
27132513TNF-α modulates genome-wide redistribution of οNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.Oncogene2016
24662829A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.Oncogene2015
25916672Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling.Nat Commun2015
26301570Tryptophan probes reveal residue-specific phospholipid interactions of apolipoprotein C-III.Biochim Biophys Acta2015
26191074miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1.Front Genet2015
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Collaborators

Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 74
National Cancer Institute, National Institutes of Health
Co-authored papers 25
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
Co-authored papers 23
Co-authored papers 23
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 16
Center for Cancer Research, National Cancer Institute
Co-authored papers 15
From Foundation Medicine
Co-authored papers 13
Zhujiang Hospital, Southern Medical University
Co-authored papers 8
INSERM U, PSL Research University, Institut Curie Research Center
Co-authored papers 8
Suburban Hospital Department of Pathology
Co-authored papers 6
National Cancer Institute, National Institutes of Health
Co-authored papers 5
Osteosarcoma Institute
Co-authored papers 5
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 4
West China Second Hospital, Sichuan University
Co-authored papers 4
University of California San Francisco
Co-authored papers 4
Co-authored papers 3
National Cancer Institute (NCI), National Institutes of Health (NIH)
Co-authored papers 3
National Cancer Institute, Center for Cancer Research
Co-authored papers 3
Departments of Bioinformatics and Clinical Genomics, Illumina Inc.
Co-authored papers 3
Yonsei University College of Medicine, Republic of Korea S. Biomedics Co.
Co-authored papers 3
National Cancer Institute
Co-authored papers 3
University of Virginia
Co-authored papers 3
Inc.Foster CityCA.
Co-authored papers 3
Nanfang Hospital and Basic Medical College, Southern Medical University
Co-authored papers 3
Illumina Inc.
Co-authored papers 3
Westmead Institute for Medical Research, University of Sydney
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Westmead Institute for Medical Research, The University of Sydney
Co-authored papers 2
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2