Author details

Full Name

Iain C Macaulay

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37225862	Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells.		2023
37796765	Identification of a non-canonical ciliate nuclear genetic code where UAA and UAG code for different amino acids.		2023
37786726	Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons.		2023
38054620	Automated Purification of DNA Origami with SPRI Beads.		2023
37770432	Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.	Nat Commun	2023
37370129	Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.	Genome Biol	2023
35537880	Into the multiverse: advances in single-cell multiomic profiling.	Trends in Genetics	2022
35377414	High expression of the MADS-box gene VRT2 increases the number of rudimentary basal spikelets in wheat.	Plant Physiology	2022
36061866	Computational prediction and experimental validation of <i>Salmonella</i> Typhimurium SopE-mediated fine-tuning of autophagy in intestinal epithelial cells.	Front Cell Infect Microbiol	2022
36125951	Single-cell genomics reveals population structures from evolutionary studies of .	Microbial genomics	2022
34880245	Free fatty-acid transport via CD36 drives Î²-oxidation-mediated hematopoietic stem cell response to infection.	Nature Communications	2021
33587817	Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment.	J Thromb Haemost	2021
33615674	Meiosis and beyond - understanding the mechanistic and evolutionary processes shaping the germline genome.	Biological Reviews	2021
33602930	Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients.	Nat Commun	2021
34734190	Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.	Nat Cancer	2021
33225533	A low-cost pipeline for soil microbiome profiling.	MicrobiologyOpen	2020
32396200	Sequencing smart: De novo sequencing and assembly approaches for a non-model mammal.	GigaScience	2020
30401703	Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.	Blood	2019
31727843	ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection.	Proceedings of the National Academy of Sciences of the United States of America	2019
31624491	Spatially resolved transcriptomics reveals plant host responses to pathogens.	Plant Methods	2019
29493594	Erratum: Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.	Nature	2018
29928511	SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements.	Cell Discov	2018
29644800	Defining Cell Identity with Single-Cell Omics.	Proteomics	2018
28089370	Single-Cell Multiomics: Multiple Measurements from Single Cells.	Trends Genet	2017
28768204	Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation.	Cell Rep	2017
28538171	Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.	Cell Rep	2017
29186120	Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.	Nature	2017
28087841	Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types.	Genome Res	2017
28263961	Power analysis of single-cell RNA-sequencing experiments.	Nat Methods	2017
28052056	Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.	Nature	2017
27685099	Separation and parallel sequencing of the genomes and transcriptomes of single cells using G&T-seq.	Nat Protoc	2016
26752769	Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.	Nat Methods	2016
26804912	Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells.	Cell Rep	2016
27015307	Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos.	Cell	2016
27383781	Resolving early mesoderm diversification through single-cell expression profiling.	Nature	2016
27009448	Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.	Nat Commun	2016
26694097	Dynamic spatio-temporal contribution of single Î²5t+ cortical epithelial precursors to the thymus medulla.	Eur J Immunol	2016
27695000	Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.	Nat Immunol	2016
26323090	Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes.	PLoS ONE	2015
25915121	G&T-seq: parallel sequencing of single-cell genomes and transcriptomes.	Nat Methods	2015
25664528	Decoding the regulatory network of early blood development from single-cell gene expression measurements.	Nat Biotechnol	2015
26004780	Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations.	Cell Stem Cell	2015
25980517	PDGFRÎ± demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium.	Nature Communications	2015
25224068	Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.	Genome Res	2014
25258084	Transcriptional diversity during lineage commitment of human blood progenitors.	Science	2014
24497842	Single cell genomics: advances and future perspectives.	PLoS Genet	2014
24835589	Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.	Cancer Cell	2014
23727242	FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.	Cell Rep	2013
23934107	Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.	Nature	2013
24054998	Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.		2013