|
| 33540918 | Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose. | Antioxidants | 2021 |
| 32637608 | Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. | Sci Adv | 2020 |
| 31947584 | Signaling Response to Transient Redox Stress in Human Isolated T Cells: Molecular Sensor Role of Syk Kinase and Functional Involvement of IL2 Receptor and L-Selectine. | Sensors | 2020 |
| 32759276 | Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype. | Sci Transl Med | 2020 |
| 30723303 | Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours. | British Journal of Cancer | 2019 |
| 29764854 | Preclinical Antitumor Activity of a Novel Anti-c-KIT Antibody-Drug Conjugate against Mutant and Wild-type c-KIT-Positive Solid Tumors. | Clinical Cancer Research | 2018 |
| 28561063 | Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer. | Nat Commun | 2017 |
| 27716743 | Ruxolitinib therapy and telomere length in myelofibrosis. | Blood Cancer Journal | 2016 |
| 27473052 | Telomere length shortening is associated with treatment-free remission in chronic myeloid leukemia patients. | Journal of Hematology and Oncology | 2016 |
| 24816908 | Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab. | Targeted Oncology | 2015 |
| 25632036 | IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies. | Sci Transl Med | 2015 |
| 25572700 | T cell tyrosine phosphorylation response to transient redox stress. | Cellular Signalling | 2015 |
| 26243863 | HER2 activating mutations are targets for colorectal cancer treatment. | Cancer Discov | 2015 |
| 24685132 | Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3. | Cell Rep | 2014 |
| 25071179 | Astrocytes contribute to gamma oscillations and recognition memory. | Proc Natl Acad Sci U S A | 2014 |
| 23729478 | Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer. | Cancer Discov | 2013 |
| 22562252 | Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer. | Oncogene | 2013 |
| 24122767 | TRAIL receptor agonist conatumumab with modified FOLFOX6 plus bevacizumab for first-line treatment of metastatic colorectal cancer: A randomized phase 1b/2 trial. | Cancer | 2013 |
| 23665971 | MACC1 mRNA levels predict cancer recurrence after resection of colorectal cancer liver metastases. | Ann Surg | 2013 |
| 23510984 | A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer. | Annals of Oncology | 2013 |
| 23370314 | A randomized phase 2 study of paclitaxel and carboplatin with or without conatumumab for first-line treatment of advanced non-small-cell lung cancer. | Journal of Thoracic Oncology | 2013 |
| 21500189 | A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors. | Int J Cancer | 2012 |
| 22753922 | International, randomized, placebo-controlled, double-blind phase III study of motesanib plus carboplatin/paclitaxel in patients with advanced nonsquamous non-small-cell lung cancer: MONET1. | J Clin Oncol | 2012 |
| 22700995 | A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer. | Ann Oncol | 2012 |
| 22392911 | Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas. | Clin Cancer Res | 2012 |
| 22455973 | Microvesicles derived from endothelial progenitor cells enhance neoangiogenesis of human pancreatic islets. | Cell Transplant | 2012 |
| 21447729 | Genetic and expression analysis of MET, MACC1, and HGF in metastatic colorectal cancer: response to met inhibition in patient xenografts and pathologic correlations. | Clin Cancer Res | 2011 |
| 22586653 | A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer. | Cancer Discov | 2011 |
| 21286667 | Molecular analysis of Fanconi anemia and mismatch repair genes in patients with colorectal carcinoma. | Oncology Reports | 2011 |
| 20628031 | Inhibition of Src impairs the growth of met-addicted gastric tumors. | Clin Cancer Res | 2010 |
| 19996456 | Only a subset of Met-activated pathways are required to sustain oncogene addiction. | Sci Signal | 2009 |
| 19559089 | In vivo manipulation of gene expression in non-human primates using lentiviral vectors as delivery vehicles. | Methods | 2009 |
| 20046894 | Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas. | Aging | 2009 |
| 20039471 | Only a subset of Met-activated pathways are required to sustain oncogene addiction. | Sci Signal | 2009 |
| 18614774 | Macrophage stimulating protein may promote tubular regeneration after acute injury. | J Am Soc Nephrol | 2008 |
| 17627301 | Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis. | Journal of Clinical Investigation | 2007 |
| 17465751 | Creating prodynorphin-expressing stem cells alerted for a high-throughput of cardiogenic commitment. | Regenerative Medicine | 2007 |
| 17267443 | Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis. | Development (Cambridge) | 2007 |
| 16473276 | Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. | Cancer Cell | 2006 |
| 16874803 | Fate of endogenous stem/progenitor cells following spinal cord injury. | Journal of Comparative Neurology | 2006 |
| 17050683 | Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates. | Proceedings of the National Academy of Sciences of the United States of America | 2006 |
| 16981910 | Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation. | Am J Transplant | 2006 |
| 15572598 | A role for bone marrow-derived cells in the vasculature of noninjured CNS. | Blood | 2005 |
| 15585415 | Development of ecdysone-regulated lentiviral vectors. | Molecular Therapy | 2005 |
| 15123829 | CRE recombinase-inducible RNA interference mediated by lentiviral vectors. | Proceedings of the National Academy of Sciences of the United States of America | 2004 |
| 12912919 | Reversal of human cellular senescence: roles of the p53 and p16 pathways. | EMBO J | 2003 |
| 12543651 | Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES. | Antimicrobial Agents and Chemotherapy | 2003 |
| 14614508 | CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. | Nature | 2003 |
| 12351379 | Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors. | Blood | 2002 |
| 11892251 | Opportunities for the use of lentiviral vectors in human gene therapy. | Current Topics in Microbiology and Immunology | 2002 |