Author details

Full Name

Yixuan Zhang

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36459715	Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.	Redox Biology	2022
36307318	Corrigendum to "Diagnostic and predictive values of circulating tetrahydrobiopterin levels as a novel biomarker in patients with thoracic and abdominal aortic aneurysms" [Redox Biol. 56 (2022) 102444].	Redox Biol	2022
35651727	Reversal of NADPH Oxidase-Dependent Early Oxidative and Inflammatory Responses in Chronic Obstructive Pulmonary Disease by Puerarin.	Oxidative Medicine and Cellular Longevity	2022
35830752	Novel and robust treatment of pulmonary hypertension with netrin-1 and netrin-1-derived small peptides.	Redox Biology	2022
35624768	Flavored and Nicotine-Containing E-Cigarettes Induce Impaired Angiogenesis and Diabetic Wound Healing via Increased Endothelial Oxidative Stress and Reduced NO Bioavailability.	Antioxidants	2022
36116158	Diagnostic and predictive values of circulating tetrahydrobiopterin levels as a novel biomarker in patients with thoracic and abdominal aortic aneurysms.	Redox Biol	2022
34509916	Therapeutic application of estrogen for COVID-19: Attenuation of SARS-CoV-2 spike protein and IL-6 stimulated, ACE2-dependent NOX2 activation, ROS production and MCP-1 upregulation in endothelial cells.	Redox Biology	2021
34176283	Targeting MicroRNA-192-5p, a Downstream Effector of NOXs (NADPH Oxidases), Reverses Endothelial DHFR (Dihydrofolate Reductase) Deficiency to Attenuate Abdominal Aortic Aneurysm Formation.	Hypertension	2021
34127487	Toll-Like Receptor 2 (TLR2) Knockout Abrogates Diabetic and Obese Phenotypes While Restoring Endothelial Function via Inhibition of NOX1.		2021
34025456	More to Explore: Further Definition of Risk Factors for COPD - Differential Gender Difference, Modest Elevation in PM., and e-Cigarette Use.	Frontiers in Physiology	2021
33126053	Targeting feed-forward signaling of TGFÎ²/NOX4/DHFR/eNOS uncoupling/TGFÎ² axis with anti-TGFÎ² and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics.	Redox Biology	2021
31591535	NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets.	Nature Reviews Cardiology	2020
30954686	Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.	Redox Biology	2019
30571557	Novel Treatment of Hypertension by Specifically Targeting E2F for Restoration of Endothelial Dihydrofolate Reductase and eNOS Function Under Oxidative Stress.	Hypertension	2019
27912196	NOX isoforms in the development of abdominal aortic aneurysm.	Redox Biology	2017
28583438	Editorial commentary: Endothelial-to-mesenchymal transition: When the good one goes bad.	Trends in Cardiovascular Medicine	2017
28366876	Endothelial cell calpain as a critical modulator of angiogenesis.	Biochimica et Biophysica Acta - Molecular Basis of Disease	2017
27872190	Protein Phosphotyrosine Phosphatase 1B (PTP1B) in Calpain-dependent Feedback Regulation of Vascular Endothelial Growth Factor Receptor (VEGFR2) in Endothelial Cells: IMPLICATIONS IN VEGF-DEPENDENT ANGIOGENESIS AND DIABETIC WOUND HEALING.	Journal of Biological Chemistry	2017
24962575	NADPH oxidase 4 induces cardiac arrhythmic phenotype in zebrafish.	J Biol Chem	2014
24442997	CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1.	Hepatology	2014
23223021	Amyloid-Î² induces hepatic insulin resistance in vivo via JAK2.		2013
23643589	Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase.	J Mol Cell Cardiol	2013
23469233	Gene expression profile analysis of type 2 diabetic mouse liver.	PLoS ONE	2013
21827732	Ligand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in mice.	Journal of Hepatology	2012
22476949	Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity.	Diabetologia	2012
22339580	Identification of the topology and functional domains of PAQR10.	Biochemical Journal	2012
22911796	Attenuation of p38-mediated miR-1/133 expression facilitates myoblast proliferation during the early stage of muscle regeneration.	PLoS ONE	2012
22522613	Amyloid-Î² induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway.		2012
22819981	Oxidative and nitrosative stress in the maintenance of myocardial function.	Free Radical Biology and Medicine	2012
22814753	Progesterone and adipoQ receptor 11 links ras signaling to cardiac development in zebrafish.	Arteriosclerosis, Thrombosis, and Vascular Biology	2012
21968647	PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus.	Cell Research	2012
22231784	Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis.	J Lipid Res	2012
21998399	WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis.	Diabetes	2011
20193037	Apolipoprotein A-I possesses an anti-obesity effect associated with increase of energy expenditure and up-regulation of UCP1 in brown fat.	Journal of Cellular and Molecular Medicine	2011
21622818	Modulating endothelial nitric oxide synthase: a new cardiovascular therapeutic strategy.	American Journal of Physiology - Heart and Circulatory Physiology	2011
22035495	Recent progress in the study of brown adipose tissue.	Cell and Bioscience	2011
20452699	Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22.	Journal of Hepatology	2010
19778564	Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.	Neurochem Int	2010
20857515	Overexpression of Wld(S) or Nmnat2 in mauthner cells by single-cell electroporation delays axon degeneration in live zebrafish.	J Neurosci Res	2010
20603618	RKTG inhibits angiogenesis by suppressing MAPK-mediated autocrine VEGF signaling and is downregulated in clear-cell renal cell carcinoma.	Oncogene	2010
19884349	Regulation of G-protein signaling by RKTG via sequestration of the G betagamma subunit to the Golgi apparatus.	Molecular and Cellular Biology	2010
18550569	Suppressive function of RKTG on chemical carcinogen-induced skin carcinogenesis in mouse.	Carcinogenesis	2008
18515281	RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells.	Carcinogenesis	2008
17639303	Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism.	Diabetologia	2007