Author details

Full Name

Sarah Sebastian

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36785938	Preclinical immunogenicity of an adenovirus-vectored vaccine for herpes zoster.		2023
37791379	HBV001: Phase I study evaluating the safety and immunogenicity of the therapeutic vaccine ChAdOx1-HBV.		2023
36323434	Intravenous administration of viral vectors expressing prostate cancer antigens enhances the magnitude and functionality of CD8+ T cell responses.	Journal for ImmunoTherapy of Cancer	2022
33654106	ChAdOx1-vectored Lassa fever vaccine elicits a robust cellular and humoral immune response and protects guinea pigs against lethal Lassa virus challenge.	NPJ Vaccines	2021
32455764	A Multi-Filovirus Vaccine Candidate: Co-Expression of Ebola, Sudan, and Marburg Antigens in a Single Vector.	Vaccines	2020
31740525	Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria.	Infection and Immunity	2020
32295168	The Design and Development of a Multi-HBV Antigen Encoded in Chimpanzee Adenoviral and Modified Vaccinia Ankara Viral Vectors; A Novel Therapeutic Vaccine Strategy against HBV.	Vaccines	2020
31170144	A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters.	PLoS Neglected Tropical Diseases	2019
29794983	Clinical Advances in Viral-Vectored Influenza Vaccines.	Vaccines	2018
28869761	Novel viral vectors in infectious diseases.	Immunology	2018
30301933	Development of a Molecular Adjuvant to Enhance Antigen-Specific CD8 T Cell Responses.	Scientific Reports	2018
29083948	Chimpanzee adenoviral vectors as vaccines for outbreak pathogens.	Human Vaccines and Immunotherapeutics	2017
28374245	Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector.	Methods in Molecular Biology	2017
26511884	Recombinant modified vaccinia virus Ankara-based malaria vaccines.	Expert Review of Vaccines	2016
29527232	Simian adenoviruses as vaccine vectors.	Future Virology	2016
24594931	Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca[2+] signals at key decision points in the life cycle of malaria parasites.	PLoS Biol	2014
23245327	A tetracycline-repressible transactivator system to study essential genes in malaria parasites.		2012
22817984	A Plasmodium calcium-dependent protein kinase controls zygote development and transmission by translationally activating repressed mRNAs.	Cell Host Microbe	2012
22078707	TRIM5Î± associates with proteasomal subunits in cells while in complex with HIV-1 virions.	Retrovirology	2011
19153241	An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding.	Journal of Virology	2009
17397894	The role of lysine 186 in HIV-1 integrase multimerization.	Virology	2007
17324355	The retroviral restriction factor TRIM5alpha.	Current Infectious Disease Reports	2007
16439561	Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner.	Journal of Virology	2006
16203999	Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells.	Proceedings of the National Academy of Sciences of the United States of America	2005
15919943	Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues.	Journal of Virology	2005
15967037	TRIM5alpha selectively binds a restriction-sensitive retroviral capsid.	Retrovirology	2005
14767062	HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.	Molecular Biology of the Cell	2004
15479815	Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA.	Journal of Virology	2004