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Author Details

Matthew L Freedman
Dana-Farber Cancer Institute
1993
184
62
PMIDPaper TitleJournal TitlePublished Year
36681680Epigenomic charting and functional annotation of risk loci in renal cell carcinoma.Nat Commun2023
36399432Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.Cancer Discov2023
37857693Author Correction: A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus.Nat Commun2023
38057321The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancer.Nat Commun2023
37865722Liquid biopsy epigenomic profiling for cancer subtyping.Nat Med2023
37612286A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus.Nat Commun2023
37090516Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development.bioRxiv2023
37271632Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs.Eur Urol2023
36546757Optimized high-throughput screening of non-coding variants identified from genome-wide association studies.Nucleic Acids Res2023
36993558Analysis of evolutionary dynamics and clonal architecture in prostate cancer.bioRxiv2023
36681680Epigenomic charting and functional annotation of risk loci in renal cell carcinoma.Nat Commun2023
37038004Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer.Nat Cancer2023
37865722Liquid biopsy epigenomic profiling for cancer subtyping.Nat Med2023
37857693Author Correction: A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus.Nat Commun2023
38057321The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancer.Nat Commun2023
37612286A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus.Nat Commun2023
37090516Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development.bioRxiv2023
36993558Analysis of evolutionary dynamics and clonal architecture in prostate cancer.bioRxiv2023
37038004Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer.Nat Cancer2023
37271632Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs.Eur Urol2023
36546757Optimized high-throughput screening of non-coding variants identified from genome-wide association studies.Nucleic Acids Res2023
36399432Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes.Cancer Discov2023
34907080Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis.Clin Cancer Res2022
36103646Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer.JCO Precis Oncol2022
35509021Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer.Clin Epigenetics2022
35754340Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence.Cancer Discov2022
35943799Patterns of structural variation define prostate cancer across disease states.JCI Insight2022
35562350MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets.Nat Commun2022
35492879A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes.Cell Rep Med2022
36210504Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.J Natl Cancer Inst2022
36071171Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation.Nat Genet2022
35731919The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response.Cancer Res2022
35550030CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.Elife2022
35477723ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer.Nat Commun2022
35603787Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome.JCI Insight2022
36450752Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.Nat Commun2022
35468964HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.Nat Genet2022
36526723Germline variants associated with toxicity to immune checkpoint blockade.Nat Med2022
36526722IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma.Nat Med2022
34907080Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis.Clin Cancer Res2022
35550030CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.Elife2022
35509021Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer.Clin Epigenetics2022
35477723ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer.Nat Commun2022
35731919The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response.Cancer Res2022
35468964HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.Nat Genet2022
35603787Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome.JCI Insight2022
35492879A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes.Cell Rep Med2022
35754340Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence.Cancer Discov2022
35562350MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets.Nat Commun2022
36526723Germline variants associated with toxicity to immune checkpoint blockade.Nat Med2022
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Collaborators

Dana-Farber Cancer Institute
Co-authored papers 61
University of Southern California
Co-authored papers 40
University of Southern California
Co-authored papers 36
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Harvard T. H. Chan School of Public Health
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Cedars-Sinai Medical Center
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Center for Cancer Genetic Epidemiology, University of Cambridge
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National Institute of Data Science in Health and Medicine, Xiamen University
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The Kolling Institute, University of Sydney, and Royal North Shore Hospital
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National Cancer Institute, National Institutes of Health
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Memorial Sloan Kettering Cancer Center
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University of Cambridge
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Dana-Farber Cancer Institute
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Broad Institute of Harvard and Massachusetts Institute of Technology (MIT)
Co-authored papers 17
Brigham and Women's Hospital
Co-authored papers 17
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Memorial Sloan-Kettering Cancer Center
Co-authored papers 15
International Hereditary Cancer Center, Pomeranian Medical University
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Harvard T.H. Chan School of Public Health
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David Geffen School of Medicine, University of California los angeles
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Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine
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Dana-Farber Cancer Institute
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Broad Institute of MIT and Harvard
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