Author details

Full Name

Richard D Kolodner

Affiliation

Ludwig Institute for Cancer Research San Diego Branch

ORCID

Career Start Year

1972

Papers

296

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37424007	Insights into DNA cleavage by MutL homologs from analysis of conserved motifs in eukaryotic Mlh1.	Bioessays	2023
36122480	Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair.	DNA Repair (Amst)	2022
35784486	Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair.	Front Cell Dev Biol	2022
36215471	The unstructured linker of Mlh1 contains a motif required for endonuclease function which is mutated in cancers.	Proc Natl Acad Sci U S A	2022
33417883	Ligation of newly replicated DNA controls the timing of DNA mismatch repair.	Curr Biol	2021
34552065	Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae.	Nat Commun	2021
32472073	Tumour predisposition and cancer syndromes as models to study gene-environment interactions.	Nat Rev Cancer	2020
32719125	FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination.	Proc Natl Acad Sci U S A	2020
32762846	Mechanisms underlying genome instability mediated by formation of foldback inversions in <i>Saccharomyces cerevisiae</i>.	Elife	2020
30652105	Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways.	Microb Cell	2019
31686054	Author Correction: Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners.	Nat Struct Mol Biol	2019
31821785	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31324763	Alternative splicing regulates stochastic NLRP3 activity.	Nat Commun	2019
31409704	Essential <i>Saccharomyces cerevisiae</i> genome instability suppressing genes identify potential human tumor suppressors.	Proc Natl Acad Sci U S A	2019
30827889	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31085179	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
29043616	Analyzing Genome Rearrangements in Saccharomyces cerevisiae.	Methods Mol Biol	2018
30237169	The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair.	J Biol Chem	2018
30206225	The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects.	Nat Commun	2018
30061603	Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners.	Nat Struct Mol Biol	2018
29505562	SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements.	PLoS Genet	2018
29320491	Cdc73 suppresses genome instability by mediating telomere homeostasis.	PLoS Genet	2018
28013290	Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability.	Hum Mol Genet	2017
28265089	Reconstitution of <i>Saccharomyces cerevisiae</i> DNA polymerase Îµ-dependent mismatch repair with purified proteins.	Proc Natl Acad Sci U S A	2017
28684602	Pathways and Mechanisms that Prevent Genome Instability in <i>Saccharomyces cerevisiae</i>.	Genetics	2017
26698650	A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair.	DNA Repair (Amst)	2016
27579875	Correction: Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements.	PLoS Genet	2016
27071721	A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers.	Nat Commun	2016
25956862	Exonuclease 1-dependent and independent mismatch repair.	DNA Repair (Amst)	2015
26170454	Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System.	J Biol Chem	2015
25862369	New insights into the mechanism of DNA mismatch repair.	Chromosoma	2015
24699249	DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures.	PLoS Genet	2014
25247923	Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants.	PLoS One	2014
24981171	PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair.	Mol Cell	2014
24811092	Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae.	PLoS Genet	2014
24550389	Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex.	J Biol Chem	2014
24550002	A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability.	Mol Cell Biol	2014
24710071	S-score: a scoring system for the identification and prioritization of predicted cancer genes.	PLoS One	2014
23810556	Checkpoint kinases regulate a global network of transcription factors in response to DNA damage.	Cell Rep	2013
24101514	DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals.	Proc Natl Acad Sci U S A	2013
24187148	Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins.	Proc Natl Acad Sci U S A	2013
24204293	Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway.	PLoS Genet	2013
23935535	Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements.	PLoS Genet	2013
22396658	Rapid analysis of Saccharomyces cerevisiae genome rearrangements by multiplex ligation-dependent probe amplification.	PLoS Genet	2012
23045530	Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair.	J Biol Chem	2012
23129647	Bioinformatic identification of genes suppressing genome instability.	Proc Natl Acad Sci U S A	2012
22214660	What makes the engine hum: Rad6, a cell cycle supercharger.	Cell Cycle	2012
21637792	A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements.	PLoS Genet	2011
22042866	A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.	Proc Natl Acad Sci U S A	2011
22194578	Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication.	Science	2011

1 - 50 of 296

Shannon N Owens

Howard Hughes Medical Institute, University of California davis

Career Start Year 2013

Number of shared co-authors 1

Jessica P Lao

University of California san francisco

Career Start Year 2007

Number of shared co-authors 1

Michael Chang

Columbia University Medical Center

Career Start Year 2001

Number of shared co-authors 4

Xiaolan Zhao

Memorial Sloan-Kettering Cancer Center

Career Start Year 1998

Number of shared co-authors 2

Svetlana Makovets

Institute of Cell Biology, University of Edinburgh

Career Start Year 1998

Number of shared co-authors 1

Karine Dubrana

Universite Paris Cite, Universite Paris-Saclay, INSERM

Career Start Year 1997

Number of shared co-authors 3

Ayelet Arbel-Eden

Hebrew University of Jerusalem

Career Start Year 1997

Number of shared co-authors 2

Peter H Thorpe

Queen Mary University

Career Start Year 1997

Number of shared co-authors 2

Simon J Boulton

The Francis Crick Institute

Career Start Year 1996

Number of shared co-authors 4

Robert J D Reid

Columbia University Vagelos College of Physicians & Surgeons

Career Start Year 1994

Number of shared co-authors 2

Edgar Hartsuiker

North West Cancer Research Institute, Bangor University

Career Start Year 1994

Number of shared co-authors 1

Peter J McHugh

MRC Weatherall Institute of Molecular Medicine, University of Oxford

Career Start Year 1993

Number of shared co-authors 4

Grant W Brown

University of Toronto, 1 King's College Circle

Career Start Year 1991

Number of shared co-authors 10

Ke Zhang

College of Life Science, Zhejiang University

Career Start Year 1989

Number of shared co-authors 4

Tanya T Paull

University of Texas at Austin

Career Start Year 1988

Number of shared co-authors 3

Dana L Smith

University of California san francisco

Career Start Year 1988

Number of shared co-authors 1

Stephen P Jackson

Mission Therapeutics Ltd. Glenn Berge Building

Career Start Year 1987

Number of shared co-authors 3

David Lydall

Institute for Cell and Molecular Biosciences, Newcastle University Medical School

Career Start Year 1986

Number of shared co-authors 2

Monika Tsai-Pflugfelder

Friedrich Miescher Institute for Biomedical Research

Career Start Year 1984

Number of shared co-authors 6

Bennett Van Houten

UPMC-Hillman Cancer Center, University of Pittsburgh

Career Start Year 1982

Number of shared co-authors 4

Stephen J Elledge

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School

Career Start Year 1982

Number of shared co-authors 8

Kalappa Muniyappa

Indian Institute of Science

Career Start Year 1979

Number of shared co-authors 0

Jef D Boeke

Institute for Systems Genetics, NYU School of Medicine

Career Start Year 1978

Number of shared co-authors 4

Leona D Samson

Massachusetts Institute of Technology

Career Start Year 1977

Number of shared co-authors 2

Vladimir Larionov

National Cancer Institute

Career Start Year 1977

Number of shared co-authors 2

Jasper Rine

University of California berkeley

Career Start Year 1977

Number of shared co-authors 1

Philip Hieter

University of British Columbia

Career Start Year 1974

Number of shared co-authors 7

Ronald W Davis

Stanford University

Career Start Year 1968

Number of shared co-authors 3

David Botstein

Calico Life Sciences LLC

Career Start Year 1968

Number of shared co-authors 4

Thomas E Wilson

University of Michigan ann arbor

Career Start Year 1955

Number of shared co-authors 1

row(s) 1 - 30 of 30

Winfried Edelmann

Albert Einstein College of Medicine

Co-authored papers 13

Raju Kucherlapati

Harvard Medical School

Co-authored papers 10

Huilin Zhou

Co-authored papers 10

Judy E Garber

Dana-Farber Cancer Institute

Co-authored papers 10

Hans Hombauer

German Cancer Research Center (DKFZ)

Co-authored papers 9

Claudio P Albuquerque

Co-authored papers 8

Clark Chen

University of Minnesota

Co-authored papers 7

Wolf-Dietrich Heyer

University of California davis

Co-authored papers 7

Susan T Lovett

Brandeis University

Co-authored papers 5

Daniel J Mazur

Feinberg School of Medicine, Northwestern University

Co-authored papers 5

Webster K Cavenee

Ludwig Institute for Cancer Research, University of California San Diego

Co-authored papers 4

Clark C Chen

University of Minnesota

Co-authored papers 4

David N Norris

Harvard Medical School

Co-authored papers 3

Jason E Chan

Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center

Co-authored papers 3

Anthony A James

University of California irvine

Co-authored papers 3

Marcus B Smolka

Weill Institute for Cell and Molecular Biology, Cornell University

Co-authored papers 3

David J Burn

Population Health Sciences Institute, Newcastle University

Co-authored papers 3

John F de Groot

Co-authored papers 3

Erik P Sulman

NYU Grossman School of Medicine

Co-authored papers 3

Sandro J de Souza

Universidade Federal do Rio Grande do Norte

Co-authored papers 3

Massimo Loda

Weill Medical College of Cornell University

Co-authored papers 3

Andrew K Shiau

Co-authored papers 3

James E Haber

Brandeis University

Co-authored papers 3

Frank B Furnari

University of California San Diego

Co-authored papers 3

Eric J Jaehnig

Baylor College of Medicine

Co-authored papers 3

Suely Kazue Nagahashi Marie

Co-authored papers 3

Jorge Estefano Santana de Souza

Instituto Metropole Digital, Universidade Federal do Rio Grande do Norte

Co-authored papers 2

Kenneth W Kinzler

Co-authored papers 2

Hoda Anton-Culver

University of California irvine

Co-authored papers 2

John A Tainer

The University of Texas MD Anderson Cancer Center

Co-authored papers 2

1 - 30

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