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Author Details

Amit Choudhary
Broad Institute of MIT and Harvard
2009
53
21
PMIDPaper TitleJournal TitlePublished Year
36865221FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.bioRxiv2023
37477631Proximity-inducing modalities: the past, present, and future.Chem Soc Rev2023
37339634Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.Cell Metab2023
37461636Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.bioRxiv2023
37075753FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.Cell Metab2023
36945568A molecular glue approach to control the half-life of CRISPR-based technologies.bioRxiv2023
37066279Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation.bioRxiv2023
36865221FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.bioRxiv2023
36945568A molecular glue approach to control the half-life of CRISPR-based technologies.bioRxiv2023
37339634Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.Cell Metab2023
37075753FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.Cell Metab2023
37477631Proximity-inducing modalities: the past, present, and future.Chem Soc Rev2023
37066279Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation.bioRxiv2023
37461636Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation.bioRxiv2023
36396978A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules.Nat Cell Biol2022
35385189Rational Design of Silicon-Based Zinc Ionophores.Angew Chem Int Ed Engl2022
35641438Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins.Angew Chem Int Ed Engl2022
36396978A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules.Nat Cell Biol2022
35641438Synthetic Reprogramming of Kinases Expands Cellular Activities of Proteins.Angew Chem Int Ed Engl2022
35385189Rational Design of Silicon-Based Zinc Ionophores.Angew Chem Int Ed Engl2022
33253976Chemical and optical control of CRISPR-associated nucleases.Curr Opin Chem Biol2021
34130532The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes.SLAS Discov2021
34270935Bifunctional modalities for repurposing protein function.Cell Chem Biol2021
33514654Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells.Life Sci Alliance2021
33253976Chemical and optical control of CRISPR-associated nucleases.Curr Opin Chem Biol2021
33514654Harnessing reaction-based probes to preferentially target pancreatic β-cells and β-like cells.Life Sci Alliance2021
34130532The Use of Informer Sets in Screening: Perspectives on an Efficient Strategy to Identify New Probes.SLAS Discov2021
34270935Bifunctional modalities for repurposing protein function.Cell Chem Biol2021
32403926A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems.Biochemistry2020
32175731Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells.J Am Chem Soc2020
32403926A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems.Biochemistry2020
34094293Correction: A universal method for sensitive and cell-free detection of CRISPR-associated nucleases.Chem Sci2020
33208361A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells.Sci Adv2020
33376784Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes.ACS Cent Sci2020
32792475Engineering designer beta cells with a CRISPR-Cas9 conjugation platform.Nat Commun2020
33335055Core commitments for field trials of gene drive organisms.Science2020
32787262Phosphorylation-Inducing Chimeric Small Molecules.J Am Chem Soc2020
32610142Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives.Cell Rep2020
34094293Correction: A universal method for sensitive and cell-free detection of CRISPR-associated nucleases.Chem Sci2020
33376784Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes.ACS Cent Sci2020
33335055Core commitments for field trials of gene drive organisms.Science2020
33208361A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of β cells.Sci Adv2020
32792475Engineering designer beta cells with a CRISPR-Cas9 conjugation platform.Nat Commun2020
32787262Phosphorylation-Inducing Chimeric Small Molecules.J Am Chem Soc2020
32610142Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives.Cell Rep2020
32175731Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells.J Am Chem Soc2020
30640437Precision Control of CRISPR-Cas9 Using Small Molecules and Light.Biochemistry2019
30640437Precision Control of CRISPR-Cas9 Using Small Molecules and Light.Biochemistry2019
31051099A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9.Cell2019
30996981A universal method for sensitive and cell-free detection of CRISPR-associated nucleases.Chem Sci2019
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Collaborators

Ronald T Raines
Massachusetts Institute of Technology
Co-authored papers 20
Bridget K Wagner
Co-authored papers 12
Vedagopuram Sreekanth
Co-authored papers 8
Donghyun Lim
Co-authored papers 8
Vlado Dan????k
Broad Institute
Co-authored papers 5
Stuart L Schreiber
Broad Institute
Co-authored papers 5
Paul A Clemons
Broad Institute
Co-authored papers 5
Jonas Sieber
Co-authored papers 2
Martine Therrien
Co-authored papers 2
Anne E Carpenter
Broad Institute of MIT and Harvard
Co-authored papers 2
Moran Dvela-Levitt
Co-authored papers 2
Eriene-Heidi Sidhom
Co-authored papers 2
Valentino M Gantz
University of California San Diego
Co-authored papers 2
Jillian L Shaw
Co-authored papers 2
Beth Stevens
Co-authored papers 2
Maria Kost-Alimova
Co-authored papers 2
Juan Lorenzo Pablo
Co-authored papers 2
Melina Claussnitzer
Broad Institute of MIT and Harvard
Co-authored papers 2
Shantanu Singh
Co-authored papers 2
Clary B Clish
Broad Institute of MIT and Harvard
Co-authored papers 2
Nicolas Wieder
Co-authored papers 2
Choah Kim
Co-authored papers 2
David R Liu
Co-authored papers 2
Steven A Carr
Broad Institute of MIT and Harvard
Co-authored papers 2
Hilary K Finucane
Co-authored papers 2
Ranjan Devkota
Co-authored papers 2
Eric G Sheu
Co-authored papers 2
George M Church
Harvard Medical School
Co-authored papers 2
Anna Greka
Co-authored papers 2
Jason Flannick
Co-authored papers 2
Release 1.2