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Author Details

Nagsen Gautam
2009
63
21
PMIDPaper TitleJournal TitlePublished Year
35190119Analyte recovery in LC-MS/MS bioanalysis: An old issue revisited.Analytica Chimica Acta2022
35680875Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation.Nature Communications2022
35476515Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.Proceedings of the National Academy of Sciences of the United States of America2022
35402050Urinary BA Indices as Prognostic Biomarkers for Complications Associated with Liver Diseases.International Journal of Hepatology2022
34531390Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles.Nature Communications2021
33959226Bile acid indices as biomarkers for liver diseases I: Diagnostic markers.World Journal of Hepatology2021
34103484Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir.Nature Communications2021
34312680Intramuscular and subcutaneous administration of antiretroviral drugs, compared with oral, enhances delivery to lymphoid tissues in BALB/c mice.Journal of Antimicrobial Chemotherapy2021
34131469Bile acid indices as biomarkers for liver diseases II: The bile acid score survival prognostic model.World Journal of Hepatology2021
32553670The selective PPAR-delta agonist seladelpar reduces ethanol-induced liver disease by restoring gut barrier function and bile acid homeostasis in mice.Transl Res2021
34458739Discovery, synthesis and biological characterization of a series of -(1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-methyl-1-pyrazol-5-yl)acetamide ethers as novel GIRK1/2 potassium channel activators.RSC Medicinal Chemistry2021
32609488KVA-D-88, a Novel Preferable Phosphodiesterase 4B Inhibitor, Decreases Cocaine-Mediated Reward Properties .ACS Chemical Neuroscience2020
31742407Synthesis and Characterization of Long-Acting Darunavir Prodrugs.Molecular Pharmaceutics2020
32341511A year-long extended release nanoformulated cabotegravir prodrug.Nat Mater2020
31610397Direct and indirect quantification of phosphate metabolites of nucleoside analogs in biological samples.Journal of Pharmaceutical and Biomedical Analysis2020
32908958The Synergistic Effect of an ATP-Competitive Inhibitor of mTOR and Metformin on Pancreatic Tumor Growth.Current Developments in Nutrition2020
32679269Head-to-head comparative pharmacokinetic and biodistribution (PK/BD) study of two dexamethasone prodrug nanomedicines on lupus-prone NZB/WF1 mice.Nanomedicine: Nanotechnology, Biology, and Medicine2020
33062163Synthesis and SAR Studies of 1-Pyrrolo[2,3-]pyridine-2-carboxamides as Phosphodiesterase 4B (PDE4B) Inhibitors.ACS Medicinal Chemistry Letters2020
31496683Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation.International Journal of Nanomedicine2019
30289818Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques.AIDS2019
31525692A long acting nanoformulated lamivudine ProTide.Biomaterials2019
31491432Creation of a long-acting rilpivirine prodrug nanoformulation.J Control Release2019
31472458Synthesis of a long acting nanoformulated emtricitabine ProTide.Biomaterials2019
31266936Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.Nature Communications2019
31335938Assessing the lymphoid tissue bioavailability of antiretrovirals in human primary lymphoid endothelial cells and in mice.Journal of Antimicrobial Chemotherapy2019
30718161Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators.Bioorganic and Medicinal Chemistry Letters2019
31299454Determination of the in vitro metabolic stability and metabolites of the anticancer derivative riccardin D-N in human and mouse hepatic S9 fractions using HPLC-Q-LIT-MS.Journal of Pharmaceutical and Biomedical Analysis2019
29402886Creation of a long-acting nanoformulated dolutegravir.Nature Communications2018
28975688Simultaneous LC-MS/MS analysis of eicosanoids and related metabolites in human serum, sputum and BALF.Biomedical Chromatography2018
29059541Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles.Biomaterials2018
29995046ProTide generated long-acting abacavir nanoformulations.Chemical Communications2018
29553879Optimizing the preparation and stability of decorated antiretroviral drug nanocrystals.Nanomedicine2018
29518644Simultaneous quantification of intracellular lamivudine and abacavir triphosphate metabolites by LC-MS/MS.Journal of Pharmaceutical and Biomedical Analysis2018
29785833Species differences in bile acids I. Plasma and urine bile acid composition.Journal of Applied Toxicology2018
29845631Species differences in bile acids II. Bile acid metabolism.Journal of Applied Toxicology2018
28134625Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs.Journal of Clinical Investigation2017
29061742Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques.Antimicrob Agents Chemother2017
27559685Creation of a Long-Acting Nanoformulated 2',3'-Dideoxy-3'-Thiacytidine.Journal of acquired immune deficiency syndromes (1999)2017
27565555Novel fluorinated pyrrolomycins as potent anti-staphylococcal biofilm agents: Design, synthesis, pharmacokinetics and antibacterial activities.European Journal of Medicinal Chemistry2016
27344632Quantitative analysis of endogenous compounds.Journal of Pharmaceutical and Biomedical Analysis2016
27456759Development and characterization of a long-acting nanoformulated abacavir prodrug.Nanomedicine2016
27352248Pharmacokinetic studies of a novel trioxane antimalarial (99/411) in rats and monkeys using LC-MS/MS.Biomedical Chromatography2016
25223962Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IPharmaceutical Research2015
25869245Irreversible binding of an anticancer compound (BI-94) to plasma proteins.Xenobiotica2015
25691324Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal.Journal of Antimicrobial Chemotherapy2015
25344563Urinary bile acids as biomarkers for liver diseases II. Signature profiles in patients.Toxicological Sciences2015
25344562Urinary bile acids as biomarkers for liver diseases I. Stability of the baseline profile in healthy subjects.Toxicological Sciences2015
26218293Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders.Brain, Behavior, and Immunity2015
24258703Liquid chromatography tandem mass spectrometry method for determination of antidiabetic chalcones derivative S001-469 in rat plasma, urine and feces: application to pharmacokinetic study.Drug Research2014
25288084Pharmacokinetics, biodistribution, and toxicity of folic acid-coated antiretroviral nanoformulations.Antimicrob Agents Chemother2014
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