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Author Details

Stefan Aigner
University of California San Diego
1992
70
30
PMIDPaper TitleJournal TitlePublished Year
36763002In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target.Blood Cancer Discov2023
37790334A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.bioRxiv2023
37673892A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer.Nat Commun2023
37224531Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling.Nucleic Acids Res2023
35263585Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.Cell Rep2022
35411350Wastewater sequencing uncovers early, cryptic SARS-CoV-2 variant transmission.medRxiv2022
35798029Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission.Nature2022
35703436Sentinel Cards Provide Practical SARS-CoV-2 Monitoring in School Settings.mSystems2022
35778567Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis.Acta Neuropathol2022
32929188The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1.Nat Biomed Eng2021
34909793SARS-CoV-2 Distribution in Residential Housing Suggests Contact Deposition and Correlates with <i>Rothia</i> sp.medRxiv2021
34726486Analysis of SARS-CoV-2 RNA Persistence across Indoor Surface Materials Reveals Best Practices for Environmental Monitoring Programs.mSystems2021
34508652Emergence of an early SARS-CoV-2 epidemic in the United States.Cell2021
34312621Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence.bioRxiv2021
33402748Author Correction: A large-scale binding and functional map of human RNA-binding proteins.Nature2021
32669294The <i>Thermus thermophilus</i> DEAD-box protein Hera is a general RNA binding protein and plays a key role in tRNA metabolism.RNA2020
33287884Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression.Genome Med2020
33226095In vitro evaluation of a novel immediate-release formulation of oxy-codone (RoxyBondâ¿¢) for the potential for abuse via injection.J Opioid Manag2020
33127739Handwashing and Detergent Treatment Greatly Reduce SARS-CoV-2 Viral Load on Halloween Candy Handled by COVID-19 Patients.mSystems2020
32807991Large-scale tethered function assays identify factors that regulate mRNA stability and translation.Nat Struct Mol Biol2020
32943573Context-dependent functional compensation between Ythdf m<sup>6</sup>A reader proteins.Genes Dev2020
32848060Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action.Proc Natl Acad Sci U S A2020
32673563G<sub>4</sub>C<sub>2</sub> Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD.Neuron2020
29608768A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Intranasal Human Abuse Potential Study of Oxycodone ARIR, a Novel, Immediate-Release, Abuse-Deterrent Formulation.Pain Med2019
31588046The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.Cell Stem Cell2019
31278694A Randomized, Crossover Study on the Effect of Food on the Pharmacokinetic Characteristics of Morphine ARER (MorphaBondâ¿¢ ER), an Abuse-Deterrent Formulation of Extended-Release Morphine.Adv Ther2019
31065992Relative Oral Bioavailability of an Abuse-Deterrent, Immediate-Release Formulation of Oxycodone, Oxycodone ARIR in a Randomized Study.Adv Ther2019
30990363Syringeability of morphine ARER, a novel, abuse-deterrent, extended-release morphine formulation.Am J Drug Alcohol Abuse2019
28948968Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development.Mol Psychiatry2018
30049503Relative Oral Bioavailability of an Abuse-deterrent, Extended-release Formulation of Morphine Versus Extended-release Morphine: A 2-period, Single-dose, Randomized Crossover Study in Healthy Subjects.Clin Ther2018
29849845Intranasal Pharmacokinetics of Morphine ARER, a Novel Abuse-Deterrent Formulation: Results from a Randomized, Double-Blind, Four-Way Crossover Study in Nondependent, Opioid-Experienced Subjects.Pain Res Manag2018
27651506A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Intranasal Drug Liking Study on a Novel Abuse-Deterrent Formulation of Morphine-Morphine ARER.Pain Med2017
28440309Glypican-2 levels in cerebrospinal fluid predict the status of adult hippocampal neurogenesis.Sci Rep2017
28218746Early transcriptional and epigenetic regulation of CD8<sup>+</sup> T cell differentiation revealed by single-cell RNA sequencing.Nat Immunol2017
28803727Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9.Cell2017
28925361Generation of a homozygous GBA deletion human embryonic stem cell line.Stem Cell Res2017
27052171mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis.Cell Rep2016
27655340Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model.Genome Med2016
27775709RNA-binding protein CPEB1 remodels host and viral RNA landscapes.Nat Struct Mol Biol2016
27256382Tethered Function Assays as Tools to Elucidate the Molecular Roles of RNA-Binding Proteins.Adv Exp Med Biol2016
27068461Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival.Cell Rep2016
25684324Characterization of a human pluripotent stem cell-derived model of neuronal development using multiplexed targeted proteomics.Proteomics Clin Appl2015
25880497Applications of Cas9 as an RNA-programmed RNA-binding protein.Bioessays2015
24232378Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish.Psychopharmacology (Berl)2014
24381312Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons.Hum Mol Genet2014
24292384Using genetic findings in autism for the development of new pharmaceutical compounds.Psychopharmacology (Berl)2014
23511305Multicellular self-assembled spheroidal model of the blood brain barrier.Sci Rep2013
22399759Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis.J Neurosci2012
21325059In vivo demonstration that alpha-synuclein oligomers are toxic.Proc Natl Acad Sci U S A2011
18508282Grasping the diagonal: controlling attention to illusory stimuli for action and perception.Conscious Cogn2009
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Collaborators

University of California
Co-authored papers 33
University of California, USA Institute for Genomic Medicine
Co-authored papers 14
University of California San Diego
Co-authored papers 8
University of California San Diego
Co-authored papers 6
Herbert Wertheim School of Public Health, University of California
Co-authored papers 6
University of California San Diego
Co-authored papers 6
University of California San Diego
Co-authored papers 5
University of Manchester
Co-authored papers 5
the Scripps Research Institute
Co-authored papers 3
University of California
Co-authored papers 3
The Scripps Research Institute
Co-authored papers 3
Co-authored papers 3
Rega Institute, University of Leuven
Co-authored papers 3
Roche Pharmaceutical Research and Early Development, F. Hoffmann-La Roche Ltd
Co-authored papers 3
Scripps Clinic/Scripps Green Hospital
Co-authored papers 3
The Scripps Research Institute
Co-authored papers 3
University of California San Diego
Co-authored papers 3
California Institute of Technology
Co-authored papers 2
University of California, Davis Center for Valley Fever
Co-authored papers 2
Imperial College London Diabetes Centre
Co-authored papers 2
Bonita Vista High School, University of California San Diego, University of California, San Diego
Co-authored papers 2
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Rady Children's Institute for Genomic Medicine
Co-authored papers 2
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 2
University of California San Diego
Co-authored papers 2
The Scripps Research Institute
Co-authored papers 2
Rady Children's Institute for Genomic Medicine
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of California san francisco
Co-authored papers 2