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Author Details
Full Name
Mariel O Brok
Affiliation
Princess Maxima Center for Pediatric Oncology
ORCID
Career Start Year
1995
Papers
16
H Index
13
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35916583
Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes.
EMBO Mol Med
2022
32685929
An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions.
STAR Protoc
2020
33280256
Genome-wide off-rates reveal how DNA binding dynamics shape transcription factor function.
Mol Syst Biol
2020
26700642
A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.
BMC Biol
2015
24952590
Cell cycle population effects in perturbation studies.
Mol Syst Biol
2014
24766815
Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.
Cell
2014
23185333
Exploring gene expression signatures for predicting disease free survival after resection of colorectal cancer liver metastases.
PLoS One
2012
21596317
The specificity and topology of chromatin interaction pathways in yeast.
Mol Cell
2011
21145464
Functional overlap and regulatory links shape genetic interactions between signaling pathways.
Cell
2010
18180247
Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification.
Nucleic Acids Res
2008
15970668
Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps.
Cancer Biol Ther
2005
15251980
Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.
Blood
2004
12869630
Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill.
Mol Pharmacol
2003
11854447
Inactivation of the Saccharomyces cerevisiae SKY1 gene induces a specific modification of the yeast anticancer drug sensitivity profile accompanied by a mutator phenotype.
Mol Pharmacol
2002
12385009
Deletion of chromosomal region 6q14-16 in prostate cancer.
Int J Cancer
2002
7632462
Distinct changes in HIV type 1 RNA versus p24 antigen levels in serum during short-term zidovudine therapy in asymptomatic individuals with and without progression to AIDS.
AIDS Res Hum Retroviruses
1995
1 - 16 of 16
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row(s) 1 - 30 of 30
Collaborators
Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers
10
Patrick Kemmeren
Princess Maxima Center for Pediatric Oncology
Co-authored papers
8
Marian J A Groot Koerkamp
Princess Maxima Center for Pediatric Oncology Research
Co-authored papers
7
Dik van Leenen
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University
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7
Philip Lijnzaad
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Co-authored papers
6
Sander R van Hooff
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Co-authored papers
5
Tineke L Lenstra
the Netherlands Cancer Institute, Oncode Institute
Co-authored papers
5
Joris J Benschop
Center for Molecular Medicine, University Medical Center Utrecht
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5
Thanasis Margaritis
Princess Maxima Center for Pediatric Oncology
Co-authored papers
4
Katrin Sameith
Center for Molecular and Cellular Bioengineering
Co-authored papers
4
Nathalie Brabers
University Medical Centre Utrecht, Universiteitsweg
Co-authored papers
4
Cheuk W Ko
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3
Sake van Wageningen
Oncode Institute, The Netherlands Cancer Institute
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3
Berend Snel
Utrecht University
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3
Loes A L van de Pasch
University Medical Centre Utrecht, Universiteitsweg
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3
Eva Apweiler
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Linda V Bakker
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Antony J Miles
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