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Author Details

Mauro W Costa
Australian Regenerative Medicine Institute, Monash University
1992
37
20
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37162857Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice.bioRxiv2023
346243323D-cardiomics: A spatial transcriptional atlas of the mammalian heart.J Mol Cell Cardiol2022
35182466Transcription factor protein interactomes reveal genetic determinants in heart disease.Cell2022
35293863Adult mouse fibroblasts retain organ-specific transcriptomic identity.Elife2022
32130914Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice.Cell Rep2020
30482476Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease.Mol Metab2019
30183475Enhancing the efficacy of glycolytic blockade in cancer cells <i>via</i> RAD51 inhibition.Cancer Biol Ther2019
29636455NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network.Nat Commun2018
29979676Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy.PLoS Genet2018
30110325Correction: Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy.PLoS Genet2018
28352650Point mutations in murine <i>Nkx2-5</i> phenocopy human congenital heart disease and induce pathogenic Wnt signaling.JCI Insight2017
26897459A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.Differentiation2016
27421610The cardiac fibroblast: Origin, identity and role in homeostasis and disease.Differentiation2016
25960956DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.Eur Thyroid J2015
26673252CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts.PLoS One2015
25929466VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.BMC Bioinformatics2015
24650916Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.Circ Res2014
26484127Microarray profiling to analyse adult cardiac fibroblast identity.Genom Data2014
23535658Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy.Nat Commun2013
24265804Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling.PLoS One2013
23661673Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.Circ Cardiovasc Genet2013
23620696Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases.Exp Clin Cardiol2012
21931855Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.PLoS One2011
20874241GATA4 mutations in 357 unrelated patients with congenital heart malformation.Genet Test Mol Biomarkers2010
19533775Molecular analysis of PRKAG2, LAMP2, and NKX2-5 genes in a cohort of 125 patients with accessory atrioventricular connection.Am J Med Genet A2009
19414016Conformational stability and DNA binding specificity of the cardiac T-box transcription factor Tbx20.J Mol Biol2009
18981480BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4.Genes Dev2008
17668378Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy.Am J Hum Genet2007
16510504A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery.Development2006
15843414Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation.Development2005
15537493Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5.Cardiovasc Res2004
14550786Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.Dev Biol2003
12858530Homeodomain factor Nkx2-5 in heart development and disease.Cold Spring Harb Symp Quant Biol2002
10358109Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells.J Physiol1999
8679628Identification of an Spl-like element within the immunoglobulin kappa 3' enhancer necessary for maximal enhancer activity.Biochemistry1996
8429307Molecular cloning and sequence analysis of a segment from Andean potato mottle virus B RNA encoding the putative RNA polymerase.J Gen Virol1993
1623195Complete nucleotide sequence of the 22 kDa coat protein of Andean potato mottle virus.Plant Mol Biol1992
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Cardiovascular Research Institute, University of California san francisco
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Leiden University Medical Center
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University of California San Francisco
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Gladstone Institutes San Francisco
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University of Twente
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Columbia University.
Co-authored papers 1
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Quantitative Biosciences Institute (QBI), University of California san francisco
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Boston Children's Hospital
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