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Author Details

William B Isaacs
The Brady Urological Institute, The Johns Hopkins School of Medicine
1979
510
110
PMIDPaper TitleJournal TitlePublished Year
36567534Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry.Prostate2023
37635043Aggravated Androgen Receptor Activity in Otherwise Indolent Prostate Cancer.Eur Urol2023
37945903Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.Nat Genet2023
37608028Detection of metastases using circulating tumour DNA in uveal melanoma.J Cancer Res Clin Oncol2023
37292833Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry.medRxiv2023
37311464Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.Am J Hum Genet2023
37140987Identification of long noncoding RNAs with aberrant expression in prostate cancer metastases.Endocr Relat Cancer2023
36752203Association of self-identified race and genetic ancestry with the immunogenomic landscape of primary prostate cancer.JCI Insight2023
36872133Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.Eur Urol2023
34533610Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer.Cancer Immunol Immunother2022
35347252Inherited risk assessment and its clinical utility for predicting prostate cancer from diagnostic prostate biopsies.Prostate Cancer Prostatic Dis2022
35452513Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing.Mol Cancer Res2022
36353656Reliability of Ancestry-specific Prostate Cancer Genetic Risk Score in Four Racial and Ethnic Populations.Eur Urol Open Sci2022
36353071Shared Inherited Genetics of Benign Prostatic Hyperplasia and Prostate Cancer.Eur Urol Open Sci2022
35190695Future perspectives of uveal melanoma blood based biomarkers.Br J Cancer2022
35149774KLK3 germline mutation I179T complements DNA repair genes for predicting prostate cancer progression.Prostate Cancer Prostatic Dis2022
35031163A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.Eur Urol2022
35238838The role of genetic testing in prostate cancer screening, diagnosis, and treatment.Curr Opin Oncol2022
35104804Health inequity drives disease biology to create disparities in prostate cancer outcomes.J Clin Invest2022
34674288Association of germline rare pathogenic mutations in guideline-recommended genes with prostate cancer progression: A meta-analysis.Prostate2022
34799695The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients.Br J Cancer2022
32800727Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer.Eur Urol2021
33617332Specific Detection of Prostate Cancer Cells in Urine by RNA In Situ Hybridization.J Urol2021
33724955Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer.JCI Insight2021
34885099Analysis of Circulating Tumour Cells in Early-Stage Uveal Melanoma: Evaluation of Tumour Marker Expression to Increase Capture.Cancers (Basel)2021
33958727Correction: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors.Oncogene2021
34210485Prostate Cancer Predisposition.Urol Clin North Am2021
33956350Association of prostate cancer polygenic risk score with number and laterality of tumor cores in active surveillance patients.Prostate2021
34337548Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine.Eur Urol Open Sci2021
34337532Genetic Susceptibility for Low Testosterone in Men and Its Implications in Biology and Screening: Data from the UK Biobank.Eur Urol Open Sci2021
34024654Incorporation of Polygenic Risk Score into Guidelines for Inherited Risk Assessment for Prostate Cancer.Eur Urol2021
34254341Observed evidence for guideline-recommended genes in predicting prostate cancer risk from a large population-based cohort.Prostate2021
33436325Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study.Eur Urol Oncol2021
33462368Homologous recombination deficiency (HRD) score in germline BRCA2- versus ATM-altered prostate cancer.Mod Pathol2021
33257031Performance of Three Inherited Risk Measures for Predicting Prostate Cancer Incidence and Mortality: A Population-based Prospective Analysis.Eur Urol2021
33398198Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.Nat Genet2021
33473200Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.Nat Genet2021
30908472AUSTRALIAN AND NEW ZEALAND STUDY OF PHOTODYNAMIC THERAPY IN CHOROIDAL AMELANOTIC MELANOMA.Retina2020
31948886Rare Germline Pathogenic Mutations of DNA Repair Genes Are Most Strongly Associated with Grade Group 5 Prostate Cancer.Eur Urol Oncol2020
31978561Low-Pass Whole-Genome Sequencing as a Method of Determining Copy Number Variations in Uveal Melanoma Tissue Samples.J Mol Diagn2020
33258481Validation of a prostate cancer polygenic risk score.Prostate2020
33115829Distinct Genomic Alterations in Prostate Tumors Derived from African American Men.Mol Cancer Res2020
33033260Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy.Nat Commun2020
32581009Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial.Cancer Prev Res (Phila)2020
32830201Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank.Br J Cancer2020
32803894Feasibility and performance of a novel probe panel to detect somatic DNA copy number alterations in clinical specimens for predicting prostate cancer progression.Prostate2020
32989253Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors.Oncogene2020
32694154Genomic and Clinicopathologic Characterization of ATM-deficient Prostate Cancer.Clin Cancer Res2020
32505340Corrigendum to "A systematic comparison of exercise training protocols on animal models of cardiovascular capacity" [Life Sci. 217 (2019) 128-140].Life Sci2020
32415113Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours.Nat Commun2020
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Collaborators

Jianfeng Xu
Co-authored papers 205
Henrik Gr??nberg
Karolinska Institute
Co-authored papers 82
John D Carpten
Co-authored papers 69
Fredrik Wiklund
Co-authored papers 65
George Steven Bova
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 63
Kathleen A Cooney
Duke University School of Medicine, and the Duke Cancer Institute
Co-authored papers 51
Deborah A Meyers
Co-authored papers 45
Janet L Stanford
Fred Hutchinson Cancer Research Center
Co-authored papers 43
Rosalind A Eeles
The Institute of Cancer Research
Co-authored papers 34
Johanna Schleutker
Institute of Biomedicine, University of Turku
Co-authored papers 33
Stephen J Chanock
National Cancer Institute, National Institutes of Health
Co-authored papers 31
Elaine A Ostrander
National Cancer Institute
Co-authored papers 31
Stephen N Thibodeau
Mayo Clinic
Co-authored papers 31
Douglas F Easton
University of Cambridge
Co-authored papers 30
Daniel J Schaid
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Co-authored papers 30
Christopher A Haiman
University of Southern California
Co-authored papers 28
Sonja I Berndt
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Rick A Kittles
Morehouse School of Medicine
Co-authored papers 27
Zsofia Kote-Jarai
The Institute of Cancer Research
Co-authored papers 26
Alan W Partin
The Brady Urological Institute, Johns Hopkins University School of Medicine
Co-authored papers 26
Ethan M Lange
Co-authored papers 24
Sue A Ingles
Co-authored papers 22
Graham G Giles
Co-authored papers 21
John S Witte
Stanford University School of Medicine
Co-authored papers 21
Eugene R Bleecker
Co-authored papers 21
Esther M John
Co-authored papers 19
Tamara L Lotan
Johns Hopkins University School of Medicine
Co-authored papers 19
Brian E Henderson
University of Southern California
Co-authored papers 18
Loic Le Marchand
Co-authored papers 18
Release 1.2