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Author Details

Jeremy A Squire
University of Sao Paulo
1982
344
79
PMIDPaper TitleJournal TitlePublished Year
36977733Pan-cancer genomic analysis shows hemizygous PTEN loss tumors are associated with immune evasion and poor outcome.Sci Rep2023
37482055Xp22.33p22.13 Duplication in a Male Patient Carrying a Recombinant X Chromosome Derived from an Inherited Intrachromosomal Insertion.Cytogenet Genome Res2023
37120668Precision medicine for prostate cancer-improved outcome prediction for low-intermediate risk disease using a six-gene copy number alteration classifier.Br J Cancer2023
37343766Artificial Intelligence-Based PTEN Loss Assessment as an Early Predictor of Prostate Cancer Metastasis After Surgery: A Multicenter Retrospective Study.Mod Pathol2023
32884130High throughput assessment of biomarkers in tissue microarrays using artificial intelligence: PTEN loss as a proof-of-principle in multi-center prostate cancer cohorts.Mod Pathol2021
33593207Multitarget fluorescence in situ hybridization diagnostic applications in solid and hematological tumors.Expert Rev Mol Diagn2021
34946849Epithelial-Mesenchymal Transition Signaling and Prostate Cancer Stem Cells: Emerging Biomarkers and Opportunities for Precision Therapeutics.Genes (Basel)2021
34502458The Role of Somatic Mutations on the Immune Response of the Tumor Microenvironment in Prostate Cancer.Int J Mol Sci2021
32129857Risk Stratification of Prostate Cancer Through Quantitative Assessment of PTEN Loss (qPTEN).J Natl Cancer Inst2020
32021597Partial Monosomy 4p and Trisomy 12q due to a t(4;12)(p16.3;q24.31) Familial Translocation in Two Cousins.Mol Syndromol2020
32439105The Dual Role of Serotonin in Colorectal Cancer.Trends Endocrinol Metab2020
32327707Emerging role of PTEN loss in evasion of the immune response to tumours.Br J Cancer2020
32456563Contributions of HOX genes to cancer hallmarks: Enrichment pathway analysis and review.Tumour Biol2020
31038736Serotonin synthesis protects the mouse colonic crypt from DNA damage and colorectal tumorigenesis.J Pathol2019
29339834Use of multicolor fluorescence in situ hybridization to detect deletions in clinical tissue sections.Lab Invest2018
30200929The Terry Fox Research Institute Canadian Prostate Cancer Biomarker Network: an analysis of a pan-Canadian multi-center cohort for biomarker validation.BMC Urol2018
29520053Correction to: Use of multicolor fluorescence in situ hybridization to detect deletions in clinical tissue sections.Lab Invest2018
29460925Clinical implications of PTEN loss in prostate cancer.Nat Rev Urol2018
29308088Distinct subtypes of genomic <i>PTEN</i> deletion size influence the landscape of aneuploidy and outcome in prostate cancer.Mol Cytogenet2018
29303938Increased STAT1 Expression in High Grade Serous Ovarian Cancer Is Associated With a Better Outcome.Int J Gynecol Cancer2018
28454331Centrosome amplification in chondrosarcomas: A primary cell culture and cryopreserved tumor sample study.Oncol Lett2017
28232783Complex Mosaic Ring Chromosome 11 Associated with Hemizygous Loss of 8.6 Mb of 11q24.2qter in Atypical Jacobsen Syndrome.Mol Syndromol2017
26753905Lacrimal gland anaplastic kinase-positive large B-cell lymphoma (LBCL-ALK+) with an atypical clinical presentation.Clin Exp Ophthalmol2016
26649044Extracellular Vesicles: Evolving Factors in Stem Cell Biology.Stem Cells Int2016
27917296STAT1-associated intratumoural T<sub>H</sub>1 immunity predicts chemotherapy resistance in high-grade serous ovarian cancer.J Pathol Clin Res2016
27174589Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH.Mod Pathol2016
26861919In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in situ hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgrading.Virchows Arch2016
26775196First application of the Automated QUantitative Analysis (AQUA) technique to quantify PTEN protein expression in ovarian cancer: A correlative study of NCIC CTG OV.16.Gynecol Oncol2016
26973172Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery.Expert Rev Proteomics2016
24993522PTEN loss is associated with upgrading of prostate cancer from biopsy to radical prostatectomy.Mod Pathol2015
26551891Current state of biomarkers in ovarian cancer prognosis.Future Oncol2015
26695556A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer.Br J Cancer2015
25939393A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer.Prostate2015
25983041A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195.Invest New Drugs2015
25754347ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer Cells.Clin Cancer Res2015
25605819Phase II study of PX-866 in recurrent glioblastoma.Neuro Oncol2015
25561528Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.Proc Natl Acad Sci U S A2015
25374307Composite mantle cell and primary cutaneous anaplastic large cell lymphoma: case report and review of the literature.Am J Dermatopathol2015
24835790Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.PLoS One2014
25434580Recurrent copy number alterations in prostate cancer: an in silico meta-analysis of publicly available genomic data.Cancer Genet2014
25456371Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study.Lancet Oncol2014
25264457Smoking-induced chromosomal segregation anomalies identified by FISH analysis of sperm.Mol Cytogenet2014
23136250Copy number and expression alterations of miRNAs in the ovarian cancer cell line OVCAR-3: impact on kallikrein 6 protein expression.Clin Chem2013
24237932Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer.BMC Cancer2013
23918607TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair.Clin Cancer Res2013
23908594Flavopiridol synergizes with sorafenib to induce cytotoxicity and potentiate antitumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems.Neoplasia2013
23623180Analysis of genomic abnormalities in tumors: a review of available methods for Illumina two-color SNP genotyping and evaluation of performance.Cancer Genet2013
23672928Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. A trial of the NCIC Clinical Trials Group (NCIC CTG IND 199).Gynecol Oncol2013
23720736MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.J Biol Chem2013
23433318Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics.Orphanet J Rare Dis2013
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Collaborators

Jane Bayani
Ontario Institute for Cancer Research
Co-authored papers 72
Brenda L Gallie
The Eye Cancer Clinic, Princess Margaret Cancer Centre, Hospital for Sick Children
Co-authored papers 17
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 16
Andrew J Evans
Princess Margaret Cancer Center, University Health Network.
Co-authored papers 13
James T Rutka
Hospital for Sick Children
Co-authored papers 11
Anthony M Joshua
The Kinghorn Cancer Centre, St. Vincent's Hospital Sydney
Co-authored papers 11
Suzanne Kamel-Reid
Toronto General Hospital, University Health Network, University of Toronto
Co-authored papers 10
Roseline Godbout
University of Alberta
Co-authored papers 8
Wan L Lam
British Columbia Cancer Research Institute
Co-authored papers 8
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 8
Madeline Li
University of Toronto
Co-authored papers 8
Robert G Bristow
University of Toronto
Co-authored papers 7
Tarek A Bismar
University of Calgary Cumming School of Medicine, Rockyview General Hospital
Co-authored papers 7
Theodorus H van der Kwast
University Health Network, University of Toronto
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Tamara Jamaspishvili
Queen's University
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Razqallah Hakem
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 7
Frances A Shepherd
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 6
Ladan Fazli
University of British Columbia
Co-authored papers 6
Martin E Gleave
University of British Columbia
Co-authored papers 6
Silvia Regina Caminada de Toledo
Pediatric Oncology Institute (IOP/GRAACC), Federal University of Sao Paulo
Co-authored papers 5
Anne Hakem
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Tamara L Lotan
Johns Hopkins University School of Medicine
Co-authored papers 5
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
David M Berman
Queen's University
Co-authored papers 5
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
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Peter B Dirks
The Hospital for Sick Children, University of Toronto
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Cynthia Hawkins
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Release 1.2