Author details

Full Name

Helena Friesen

Affiliation

University of Toronto

ORCID

Career Start Year

1984

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36909656	PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data.	bioRxiv	2023
38045359	Single-cell imaging of protein dynamics of paralogs reveals mechanisms of gene retention.	bioRxiv	2023
34139168	Single-cell image analysis to explore cell-to-cell heterogeneity in isogenic populations.	Cell Syst	2021
34096681	A genome-scale yeast library with inducible expression of individual genes.	Mol Syst Biol	2021
32064787	Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability.	Mol Syst Biol	2020
28768827	Ubiquitin orchestrates proteasome dynamics between proliferation and quiescence in yeast.	Mol Biol Cell	2017
28122947	Functional Analysis of Kinases and Transcription Factors in <i>Saccharomyces cerevisiae</i> Using an Integrated Overexpression Library.	G3 (Bethesda)	2017
27037080	High-Throughput Microscopy-Based Screening in Saccharomyces cerevisiae.	Cold Spring Harb Protoc	2016
27811238	Exploring genetic suppression interactions on a global scale.	Science	2016
27118708	High-Content Screening for Quantitative Cell Biology.	Trends Cell Biol	2016
26048563	CYCLoPs: A Comprehensive Database Constructed from Automated Analysis of Protein Abundance and Subcellular Localization Patterns in Saccharomyces cerevisiae.	G3 (Bethesda)	2015
25228766	Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation.	Proc Natl Acad Sci U S A	2014
23464215	Kirkpatrick-Baez microscope for hard X-ray imaging of fast ignition experiments.	Rev Sci Instrum	2013
23675312	Bck2 acts through the MADS box protein Mcm1 to activate cell-cycle-regulated genes in budding yeast.	PLoS Genet	2013
22282571	Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs.	Genome Res	2012
22579291	Exploring the yeast acetylome using functional genomics.	Cell	2012
21849475	Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin.	Mol Biol Cell	2011
22156209	Restriction of histone gene transcription to S phase by phosphorylation of a chromatin boundary protein.	Genes Dev	2011
19894211	Dual functions of Mdt1 in genome maintenance and cell integrity pathways in Saccharomyces cerevisiae.	Yeast	2010
20610658	Dissecting BAR domain function in the yeast Amphiphysins Rvs161 and Rvs167 during endocytosis.	Mol Biol Cell	2010
19458192	Regulation of cell polarity through phosphorylation of Bni4 by Pho85 G1 cyclin-dependent kinases in Saccharomyces cerevisiae.	Mol Biol Cell	2009
19823668	Dual regulation by pairs of cyclin-dependent protein kinases and histone deacetylases controls G1 transcription in budding yeast.	PLoS Biol	2009
17850263	Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast.	Mol Microbiol	2007
16394103	Characterization of the yeast amphiphysins Rvs161p and Rvs167p reveals roles for the Rvs heterodimer in vivo.	Mol Biol Cell	2006
16762047	Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae.	J Biol	2006
15802519	Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking.	Genetics	2005
16024810	Components of the ESCRT pathway, DFG16, and YGR122w are required for Rim101 to act as a corepressor with Nrg1 at the negative regulatory element of the DIT1 gene of Saccharomyces cerevisiae.	Mol Cell Biol	2005
14764870	Global mapping of the yeast genetic interaction network.	Science	2004
12857883	Regulation of the yeast amphiphysin homologue Rvs167p by phosphorylation.	Mol Biol Cell	2003
14659014	Yeast functional genomics and cell biology: no longer in the dark.	Genome Biol	2003
9725830	Spe3, which encodes spermidine synthase, is required for full repression through NRE(DIT) in Saccharomyces cerevisiae.	Genetics	1998
9742092	NDT80 and the meiotic recombination checkpoint regulate expression of middle sporulation-specific genes in Saccharomyces cerevisiae.	Mol Cell Biol	1998
8972192	An Ssn6-Tup1-dependent negative regulatory element controls sporulation-specific expression of DIT1 and DIT2 in Saccharomyces cerevisiae.	Mol Cell Biol	1997
7958886	Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation.	Genes Dev	1994
1593623	Mutagenesis of a conserved region of the gene encoding the FLP recombinase of Saccharomyces cerevisiae. A role for arginine 191 in binding and ligation.	J Mol Biol	1992
6087662	A molecular method for detecting the presence of the human Y chromosome.	Am J Med Genet	1984

1 - 36 of 36

Jiewei Xu

Quantitative Biosciences Institute (QBI), University of California san francisco

Career Start Year 2012

Number of shared co-authors 4

Matthew Jessulat

University of Regina

Career Start Year 2006

Number of shared co-authors 6

Li Ni

College of Life Science, Shaanxi Normal University

Career Start Year 2001

Number of shared co-authors 4

Allyson F O'Donnell

University of Pittsburgh

Career Start Year 2000

Number of shared co-authors 1

Michael Davey

BC Children's Hospital Research Institute, University of British Columbia

Career Start Year 2000

Number of shared co-authors 5

Assen Roguev

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Career Start Year 2000

Number of shared co-authors 10

Peter H Thorpe

Queen Mary University

Career Start Year 1997

Number of shared co-authors 1

Chandra L Theesfeld

Lewis-Sigler Institute for Integrative Genomics, Princeton University

Career Start Year 1996

Number of shared co-authors 13

Tsuyoshi Miyake

University of Virginia School of Medicine

Career Start Year 1995

Number of shared co-authors 0

Kristin Baetz

Ottawa Institute of Systems Biology, University of Ottawa, University of Calgary

Career Start Year 1994

Number of shared co-authors 11

Aim??e M Dudley

Pacific Northwest Research Institute

Career Start Year 1994

Number of shared co-authors 2

Won-Ki Huh

Seoul National University

Career Start Year 1991

Number of shared co-authors 5

J??rg B??hler

University College London

Career Start Year 1991

Number of shared co-authors 12

Erin K O'Shea

Howard Hughes Medical Institute

Career Start Year 1989

Number of shared co-authors 2

Eric G D Muller

University of Washington

Career Start Year 1989

Number of shared co-authors 1

John D Aitchison

Center for Global Infectious Disease Research, Seattle Children's Research Institute

Career Start Year 1988

Number of shared co-authors 3

Michele H Jones

University of Colorado Boulder

Career Start Year 1987

Number of shared co-authors 0

Mar??a Molina

UCM & Instituto Ramon y Cajal de Investigaciones Sanitarias (IRYCIS)

Career Start Year 1987

Number of shared co-authors 1

Mark Winey

University of California davis

Career Start Year 1986

Number of shared co-authors 3

Ursula Fleig

Institute of Functional Microbial Genomics, Heinrich-Heine-University

Career Start Year 1986

Number of shared co-authors 1

Hiten D Madhani

University of California san francisco

Career Start Year 1986

Number of shared co-authors 7

Yolanda Sanchez

Collegeville

Career Start Year 1985

Number of shared co-authors 1

Stanley Fields

University of Washington

Career Start Year 1985

Number of shared co-authors 7

Mark Johnston

University of Colorado School of Medicine

Career Start Year 1984

Number of shared co-authors 7

David G Drubin

University of California berkeley

Career Start Year 1983

Number of shared co-authors 10

Trisha N Davis

University of Washington

Career Start Year 1982

Number of shared co-authors 7

Michael Shales

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Career Start Year 1980

Number of shared co-authors 10

Pamela A Silver

Harvard Medical School

Career Start Year 1979

Number of shared co-authors 3

Curt Wittenberg

The Scripps Research Institute

Career Start Year 1978

Number of shared co-authors 2

Philip Hieter

University of British Columbia

Career Start Year 1974

Number of shared co-authors 16

row(s) 1 - 30 of 30

Brenda J Andrews

University of Toronto

Co-authored papers 27

Charles Boone

University of Toronto

Co-authored papers 12

Michael Costanzo

Co-authored papers 3

Chad L Myers

University of Minnesota - Twin Cities

Co-authored papers 3

Jason Moffat

University of Toronto

Co-authored papers 2

Zhijian Li

University of Toronto

Co-authored papers 2

Mike Tyers

Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal

Co-authored papers 2

Frederick P Roth

University of Toronto

Co-authored papers 2

Jeffrey Fillingham

Toronto Metropolitan University

Co-authored papers 2

Amy Hin Yan Tong

University of Toronto

Co-authored papers 2

Patrick Aloy

Institucio Catalana de Recerca i Estudis Avancats (ICREA)

Co-authored papers 2

Ashton Breitkreutz

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Co-authored papers 2

Ainslie B Parsons

University of Toronto

Co-authored papers 2

David Botstein

Calico Life Sciences LLC

Co-authored papers 2

Anne-Claude Gingras

Lunenfeld-Tanenbaum Research Institute

Co-authored papers 2

Christine Humphries

University of Toronto

Co-authored papers 2

Carles Pons

Co-authored papers 2

Yuen Ho

University of Toronto

Co-authored papers 2

Jennifer Haynes

Joan C. Edwards School of Medicine, Marshall University

Co-authored papers 1

Joshua N Levinson

MedStar Washington Hospital Center

Co-authored papers 1

Patrice Menard

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark

Co-authored papers 1

Guillaume Lesage

Institute of Molecular Biology, University of Zurich

Co-authored papers 1

Chris Sander

Broad Institute of MIT and Harvard

Co-authored papers 1

Rose Oughtred

Lewis-Sigler Institute for Integrative Genomics, Princeton University

Co-authored papers 1

Grace He

Co-authored papers 1

Xin Cheng

New York University School of Medicine

Co-authored papers 1

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 1

Gary C Hon

Cecil H. and Ida Green Center for Reproductive Biology Sciences

Co-authored papers 1

Lan V Zhang

Harvard Medical School

Co-authored papers 1

Anne-Marie Sdicu

McGill University

Co-authored papers 1

1 - 30

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