Author details

Full Name

Alec J Hirsch

Affiliation

Vaccine & Gene Therapy Institute, Oregon Health & Science University

ORCID

Career Start Year

1992

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36682515	Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease.	Brain Behav Immun	2023
37923717	Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.	Nat Commun	2023
35172138	Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination.	Cell Rep	2022
35755126	Titration and neutralizing antibody quantification by focus forming assay for Powassan virus.	STAR Protoc	2022
34696518	Nonhuman Primate Models of Zika Virus Infection and Disease during Pregnancy.	Viruses	2021
33835811	Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.	J Med Chem	2021
31616920	Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques.	J Infect Dis	2020
31935257	A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.	PLoS One	2020
32117091	The E3 Ubiquitin Ligase SIAH1 Targets MyD88 for Proteasomal Degradation During Dengue Virus Infection.	Front Microbiol	2020
32367369	Isolation and Detection of Zika Virus-Infected Rhesus Macaques Lymph Node Cells and Splenocytes.	Methods Mol Biol	2020
32367359	Analysis of Serum Anti-Zika Virus Antibodies by Focus Reduction Neutralization Test.	Methods Mol Biol	2020
31413072	Risk of Zika microcephaly correlates with features of maternal antibodies.	J Exp Med	2019
31747595	Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency.	Cell Rep	2019
29343712	Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology.	Nat Commun	2018
29967348	Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates.	Nat Med	2018
29709563	Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions.	Antiviral Res	2018
28465426	A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.	mBio	2017
28278237	Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.	PLoS Pathog	2017
28380070	Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues.	PLoS Pathog	2017
28148804	A MicroRNA Screen Identifies the Wnt Signaling Pathway as a Regulator of the Interferon Response during Flavivirus Infection.	J Virol	2017
24599995	Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling.	J Virol	2014
23824813	Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.	J Virol	2013
22345437	Induction of the cellular microRNA, Hs_154, by West Nile virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors.	J Virol	2012
21795337	Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence.	J Virol	2011
20143951	The use of RNAi-based screens to identify host proteins involved in viral replication.	Future Microbiol	2010
21151986	Immune response to the West Nile virus in aged non-human primates.	PLoS One	2010
20973722	High-content assay to identify inhibitors of dengue virus infection.	Assay Drug Dev Technol	2010
19369347	West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function.	J Virol	2009
19901080	Key role of T cell defects in age-related vulnerability to West Nile virus.	J Exp Med	2009
18385233	West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of alphavbeta3 integrin.	J Virol	2008
17452483	Sultam thiourea inhibition of West Nile virus.	Antimicrob Agents Chemother	2007
17686866	West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis.	J Virol	2007
16140770	The Src family kinase c-Yes is required for maturation of West Nile virus particles.	J Virol	2005
15254210	Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12.	J Virol	2004
9847345	Human cytomegalovirus inhibits transcription of the CC chemokine MCP-1 gene.	J Virol	1999
8196652	A novel basic helix-loop-helix protein is expressed in muscle attachment sites of the Drosophila epidermis.	Mol Cell Biol	1994
8458019	Homologous sensitisation of embryonic chick atrial myocytes to adenosine: mediation by adenosine A1 receptor and guanine nucleotide binding protein.	Cardiovasc Res	1993
1619916	Molecular mechanism of contractile dysfunction in cardiac allograft rejection.	J Surg Res	1992

1 - 38 of 38

Kathleen M Voss

Center for Innate Immunity and Immune Disease, University of Washington

Career Start Year 2016

Number of shared co-authors 6

Veronica V Rezelj

Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)

Career Start Year 2015

Number of shared co-authors 2

David Sachs

Icahn School of Medicine at Mount Sinai

Career Start Year 2013

Number of shared co-authors 0

Chao Shan

Wuhan Institute of Virology, Chinese Academy of Sciences

Career Start Year 2012

Number of shared co-authors 1

Romel Rosales

Icahn School of Medicine at Mount Sinai

Career Start Year 2012

Number of shared co-authors 0

Maxime Chazal

CNRS UMR9, Institut Pasteur, Universite de Paris Cite

Career Start Year 2012

Number of shared co-authors 0

Vinod R M T Balasubramaniam

Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia

Career Start Year 2011

Number of shared co-authors 1

Craig B Wilen

Yale School of Medicine

Career Start Year 2010

Number of shared co-authors 3

Xuping Xie

University of Texas Medical Branch

Career Start Year 2010

Number of shared co-authors 4

Hans-Heinrich Hoffmann

The Rockefeller University

Career Start Year 2008

Number of shared co-authors 2

Kristin L McNally

National Institute of Allergy and Infectious Diseases

Career Start Year 2008

Number of shared co-authors 1

Alexander N Freiberg

University of Texas Medical Branch

Career Start Year 2008

Number of shared co-authors 2

Colm Atkins

Rutgers University

Career Start Year 2007

Number of shared co-authors 0

Koen Bartholomeeusen

Institute of Tropical Medicine

Career Start Year 2007

Number of shared co-authors 0

Shannan L Rossi

Institute for Human Infection and Immunity, University of Texas Medical Branch

Career Start Year 2005

Number of shared co-authors 3

Prasad N Paradkar

DUKE-NUS Graduate Medical School

Career Start Year 2004

Number of shared co-authors 1

Nolwenn Jouvenet

CNRS UMR9, Institut Pasteur, Universite de Paris Cite

Career Start Year 2003

Number of shared co-authors 1

Yaw Shin Ooi

Duke-NUS Medical School

Career Start Year 2003

Number of shared co-authors 0

Shirit Einav

Stanford University School of Medicine

Career Start Year 2002

Number of shared co-authors 1

Sonja M Best

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Career Start Year 1998

Number of shared co-authors 3

J??rgen Haas

University of Edinburgh

Career Start Year 1996

Number of shared co-authors 1

Christopher F Basler

Icahn School of Medicine at Mount Sinai

Career Start Year 1996

Number of shared co-authors 3

Pei-Yong Shi

University of Texas Medical Branch

Career Start Year 1996

Number of shared co-authors 7

Abraham L Brass

University of Massachusetts Medical School

Career Start Year 1995

Number of shared co-authors 1

Benhur Lee

Icahn School of Medicine at Mount Sinai

Career Start Year 1995

Number of shared co-authors 5

Sara Cherry

University of Pennsylvania

Career Start Year 1993

Number of shared co-authors 4

Robert A Davey

Boston University

Career Start Year 1991

Number of shared co-authors 0

Amy S Espeseth

Merck & Co., Inc.

Career Start Year 1989

Number of shared co-authors 0

Wendy Maury

Carver College of Medicine, University of Iowa

Career Start Year 1978

Number of shared co-authors 0

Robert F Garry

Tulane University School of Medicine

Career Start Year 1974

Number of shared co-authors 1

row(s) 1 - 30 of 30

Jessica L Smith