Author details

Full Name

Yongping Yang

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36848985	Rhesus macaque Bcl-6/Bcl-xL B cell immortalization: Discovery of HIV-1 neutralizing antibodies from lymph node.		2023
37766115	Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes.	Vaccines (Basel)	2023
38035446	Transcriptionally activates CCL28 expression to inhibit M2 polarization of macrophages and prevent immune escape in colorectal cancer cells.		2023
37295404	Vaccine elicitation and structural basis for antibody protection against alphaviruses.	Cell	2023
36729903	Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.	MAbs	2023
35413243	Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.	Structure	2022
36344847	Cryo-EM structures of prefusion SIV envelope trimer.	Nat Struct Mol Biol	2022
35489332	Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.	Structure	2022
34551978	Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.	Proceedings of the National Academy of Sciences of the United States of America	2021
34135892	Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.	Front Immunol	2021
34244481	Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.	Nature Communications	2021
33494381	Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses.	Vaccines (Basel)	2021
34788599	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.	Immunity	2021
33238130	Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.	Cell Reports	2020
32268107	Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition.	Cell Rep	2020
32295908	Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.	Journal of Virology	2020
31004012	Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.	Sci Immunol	2019
31893251	Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B.	Pathogens and Immunity	2019
30604750	Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.	Nature Communications	2019
29548671	A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.	Immunity	2018
29867235	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.	Nat Med	2018
30420505	Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.	Proc Natl Acad Sci U S A	2018
29451984	Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.	ACS Infect Dis	2018
28275193	Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.	Journal of Virology	2017
28445724	Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.	Cell Rep	2017
28930230	Angelica sinensis (Oliv.) Diels: Influence of Value Chain on Quality Criteria and Marker Compounds Ferulic Acid and Z-Ligustilide.		2017
29021918	Protection of calves by a prefusion-stabilized bovine RSV F vaccine.	npj Vaccines	2017
29212041	Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains.	Cell Reports	2017
26689967	Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.	Nat Struct Mol Biol	2016
27114034	Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G.	Cell	2016
27299673	Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.	PLoS One	2016
27053554	Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.	J Virol	2016
27174988	Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.	Science	2016
27478931	Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.	Nat Struct Mol Biol	2016
27477385	Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.	Structure	2016
27463224	Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus.	PLoS One	2016
26098893	A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus.	PLoS One	2015
25740988	Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.	Journal of Virology	2015
25865483	Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.	Cell	2015
26098315	Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.	Nat Struct Mol Biol	2015
26004070	Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.	Cell	2015
26468324	Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera.	Sci Transl Med	2015
25001301	Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.	Antimicrobial Agents and Chemotherapy	2014
25296255	Structure and immune recognition of trimeric pre-fusion HIV-1 Env.	Nature	2014
24335316	Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6.	Journal of Virology	2014
24489681	Crystal structures of HIV-1 gp120 envelope glycoprotein in complex with NBD analogues that target the CD4-binding site.	PLoS ONE	2014
24484595	Chemical constituents of Euphorbia tibetica and their biological activities.	Chinese Journal of Natural Medicines	2014
24590074	Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.	Nature	2014
25142607	Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.	J Virol	2014
25165110	Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection.	Journal of Virology	2014