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Author Details
Full Name
Jeff P Bruce
Affiliation
Princess Margaret Cancer Centre, University Health Network
ORCID
Career Start Year
2010
Papers
54
H Index
29
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36833203
Molecular Genetic Characteristics of <i>FANCI</i>, a Proposed New Ovarian Cancer Predisposing Gene.
Genes (Basel)
2023
37481477
Germline whole genome sequencing in adults with multiple primary tumors.
Fam Cancer
2023
37327320
Identifying Mechanisms of Resistance by Circulating Tumor DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at Time of PARP Inhibitor Progression.
Clin Cancer Res
2023
34556523
Mutations in Noncoding <i>Cis</i>-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer.
Mol Cancer Res
2022
35379580
All is not lost: learning from 9p21 loss in cancer.
Trends Immunol
2022
36875717
Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer.
Cancer Res Commun
2022
36037303
A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.
Clin Cancer Res
2022
36129469
CD8+ Tumor-Infiltrating Lymphocyte Abundance Is a Positive Prognostic Indicator in Nasopharyngeal Cancer.
Clin Cancer Res
2022
35896551
Author Correction: Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.
Nat Commun
2022
36328595
Myeloma immunoglobulin rearrangement and translocation detection through targeted capture sequencing.
Life Sci Alliance
2022
33417860
Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy.
Cell
2021
33485453
Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet
2021
33633121
Elevation in viral entry genes and innate immunity compromise underlying increased infectivity and severity of COVID-19 in cancer patients.
Sci Rep
2021
34861889
A functionally impaired missense variant identified in French Canadian families implicates FANCI as a candidate ovarian cancer-predisposing gene.
Genome Med
2021
34446728
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity.
Nat Commun
2021
34234122
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape.
Nat Commun
2021
31521748
Translational genomics of nasopharyngeal cancer.
Semin Cancer Biol
2020
32912664
Biomarkers of outcome to weekly paclitaxel in epithelial ovarian cancer.
Gynecol Oncol
2020
32586280
MiR-34c downregulation leads to SOX4 overexpression and cisplatin resistance in nasopharyngeal carcinoma.
BMC Cancer
2020
32444417
EVOLVE: A Multicenter Open-Label Single-Arm Clinical and Translational Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer after PARP Inhibition Progression.
Clin Cancer Res
2020
32345369
Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor.
Genome Med
2020
31303643
Safety and tolerability of CFI-400945, a first-in-class, selective PLK4 inhibitor in advanced solid tumours: a phase 1 dose-escalation trial.
Br J Cancer
2019
31836588
Heterogeneous alteration of the ERBB3-MYC axis associated with MEK inhibitor resistance in a <i>KRAS</i>-mutated low-grade serous ovarian cancer patient.
Cold Spring Harb Mol Case Stud
2019
29590101
Bamgineer: Introduction of simulated allele-specific copy number variants into exome and targeted sequence data sets.
PLoS Comput Biol
2018
30226609
hsaâ¿¿miRâ¿¿24 suppresses metastasis in nasopharyngeal carcinoma by regulating the câ¿¿Myc/epithelialâ¿¿mesenchymal transition axis.
Oncol Rep
2018
30382883
Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors.
Genome Med
2018
30380421
Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma.
Cell Rep
2018
29795279
Dysregulation of the MiR-449b target TGFBI alters the TGFβ pathway to induce cisplatin resistance in nasopharyngeal carcinoma.
Oncogenesis
2018
27827316
BRM Promoter Polymorphisms and Survival of Advanced Non-Small Cell Lung Cancer Patients in the Princess Margaret Cohort and CCTG BR.24 Trial.
Clin Cancer Res
2017
28221868
Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition.
J Clin Oncol
2017
28419078
Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis.
Br J Cancer
2017
28775249
Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas.
Nat Commun
2017
28006061
The KRAS Variant as a Predictive Biomarker of Cetuximab Response in Head and Neck Cancer.
JAMA Oncol
2017
27010835
Human Papillomavirus Genotype Association With Survival in Head and Neck Squamous Cell Carcinoma.
JAMA Oncol
2016
27723760
The genomic landscape of schwannoma.
Nat Genet
2016
27121877
MicroRNAs in nasopharyngeal carcinoma.
Chin Clin Oncol
2016
27527216
HPV Associated Head and Neck Cancer.
Cancers (Basel)
2016
26983984
The complexity of microRNAs in human cancer.
J Radiat Res
2016
26934316
MiR-449a promotes breast cancer progression by targeting CRIP2.
Oncotarget
2016
25589349
Novel insights into head and neck cancer using next-generation "omic" technologies.
Cancer Res
2015
26351340
Nasopharyngeal Cancer: Molecular Landscape.
J Clin Oncol
2015
25880806
Developing a prognostic micro-RNA signature for human cervical carcinoma.
PLoS One
2015
25970788
Prognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas.
Oncotarget
2015
25944123
Chromosomal instability as a prognostic marker in cervical cancer.
BMC Cancer
2015
25738365
Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma.
Oncotarget
2015
25473903
The microRNA-218~Survivin axis regulates migration, invasion, and lymph node metastasis in cervical cancer.
Oncotarget
2015
25367334
MicroRNAs in nasopharyngeal carcinoma.
Chin J Cancer
2014
23505015
Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery.
Proteomics
2013
24145350
miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1.
Cancer Res
2013
23991213
Hemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer.
PLoS One
2013
1 - 50 of 54
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row(s) 1 - 30 of 30
Collaborators
Fei-Fei Liu
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers
29
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers
26
Wei Xu
Princess Margaret Cancer Centre
Co-authored papers
12
Wei Shi
Research Institute, Princess Margaret Cancer Centre
Co-authored papers
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Angela B Y Hui
Stanford University
Co-authored papers
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Brian O'Sullivan
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers
9
Benjamin Haibe-Kains
Princess Margaret Cancer Centre, University Health Network
Co-authored papers
6
Melania Pintilie
Princess Margaret Cancer Centre, University Health Network
Co-authored papers
5
Stephenie D Prokopec
University Health Network
Co-authored papers
5
Blaise A Clarke
University of Toronto.
Co-authored papers
5
Shao Hui Huang
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers
5
John Waldron
University of Toronto, Princess Margaret Cancer Centre, University Health Network
Co-authored papers
5
Samah El Ghamrasni
Princess Margaret Cancer Centre, University Health Network
Co-authored papers
5
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers
4
David W Cescon
Princess Margaret Cancer Centre
Co-authored papers
4
Anthony Fyles
Princess Margaret Cancer Centre, University Health Network
Co-authored papers
4
Bayardo Perez-Ordonez
University Health Network
Co-authored papers
3
Ilan Weinreb
University Health Network
Co-authored papers
3
Michael Milosevic
Princess Margaret Cancer Centre, University Health Network
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3
Richard P Hill
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Nehad M Alajez
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Patricia A Shaw
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