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Author Details

Susan C Tilton
Oregon State University
2003
61
26
PMIDPaper TitleJournal TitlePublished Year
36642108Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts.Toxicol Appl Pharmacol2023
36976966Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish.Toxics2023
37369263Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.Chem Biol Interact2023
34920278Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [<sup>14</sup>C]-BaP.Environ Int2022
35409514A Comparative Multi-System Approach to Characterizing Bioactivity of Commonly Occurring Chemicals.Int J Environ Res Public Health2022
36355943Leveraging Multiple Data Streams for Prioritization of Mixtures for Hazard Characterization.Toxics2022
34048650Linking Coregulated Gene Modules with Polycyclic Aromatic Hydrocarbon-Related Cancer Risk in the 3D Human Bronchial Epithelium.Chem Res Toxicol2021
340351253,3'-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans.Drug Metab Dispos2021
32384158Aryl Hydrocarbon Receptor Mediates Larval Zebrafish Fin Duplication Following Exposure to Benzofluoranthenes.Toxicol Sci2020
32890658Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures.Toxicol In Vitro2020
30582946Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing.Toxicol Appl Pharmacol2019
31255691Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface.Toxicol Appl Pharmacol2019
31101000Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration.BMC Bioinformatics2019
29630969Systematic developmental neurotoxicity assessment of a representative PAH Superfund mixture using zebrafish.Toxicol Appl Pharmacol2018
30398377Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA (<i>slincR</i>) Using the Zebrafish Model.Environ Health Perspect2018
29518434Pharmacokinetics of [<sup>14</sup>C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.Food Chem Toxicol2018
28833046AhR activation increases IL-2 production by alloreactive CD4<sup>+</sup> T cells initiating the differentiation of mucosal-homing Tim3<sup>+</sup> Lag3<sup>+</sup> Tr1 cells.Eur J Immunol2017
28407501Transcriptional changes in innate immunity genes in head kidneys from Aeromonas salmonicida-challenged rainbow trout fed a mixture of polycyclic aromatic hydrocarbons.Ecotoxicol Environ Saf2017
29162974Nonmonotonic Pathway Gene Expression Analysis Reveals Oncogenic Role of p27/Kip1 at Intermediate Dose.Cancer Inform2017
26867183Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism.Cell Host Microbe2016
27663205The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus.BMC Syst Biol2016
27802111Identification of Differential Gene Expression Patterns after Acute Exposure to High and Low Doses of Low-LET Ionizing Radiation in a Reconstituted Human Skin Tissue.Radiat Res2016
25655199Data integration reveals key homeostatic mechanisms following low dose radiation exposure.Toxicol Appl Pharmacol2015
26049101Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.Toxicol Appl Pharmacol2015
26141390Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.Toxicol Sci2015
25908611Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential.Toxicol Sci2015
25931120Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus.J Biol Chem2015
23659652Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression patterns.Nanotoxicology2014
25977790A comprehensive collection of systems biology data characterizing the host response to viral infection.Sci Data2014
25266609Comparative iron oxide nanoparticle cellular dosimetry and response in mice by the inhalation and liquid cell culture exposure routes.Part Fibre Toxicol2014
24846384Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.mBio2014
24720889Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways.J Biomech2014
24667235Early life perfluorooctanesulphonic acid (PFOS) exposure impairs zebrafish organogenesis.Aquat Toxicol2014
22263968Surface functionalities of gold nanoparticles impact embryonic gene expression responses.Nanotoxicology2013
23895213Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice.BMC Syst Biol2013
23935999A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses.PLoS One2013
23975936Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects.FASEB J2013
23656968Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish.Toxicol Appl Pharmacol2013
23786483Impaired transcriptional response of the murine heart to cigarette smoke in the setting of high fat diet and obesity.Chem Res Toxicol2013
23808590Dysregulation of macrophage activation profiles by engineered nanoparticles.ACS Nano2013
23557687Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish.Reprod Toxicol2013
23274566Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin.Toxicol Appl Pharmacol2013
23365422Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.J Virol2013
23306164Diet-induced obesity reprograms the inflammatory response of the murine lung to inhaled endotoxin.Toxicol Appl Pharmacol2013
22351304Cell type-dependent gene transcription profile in a three-dimensional human skin tissue model exposed to low doses of ionizing radiation: implications for medical exposures.Environ Mol Mutagen2012
23174015Bioinformatics Resource Manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools.BMC Bioinformatics2012
23000284Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish.Toxicology2012
22935520Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.Toxicol Appl Pharmacol2012
22253472MicroRNAs control neurobehavioral development and function in zebrafish.FASEB J2012
21356183Transcriptional impact of organophosphate and metal mixtures on olfaction: copper dominates the chlorpyrifos-induced response in adult zebrafish.Aquat Toxicol2011
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Collaborators

Pacific Northwest National Laboratory
Co-authored papers 29
Co-authored papers 15
Co-authored papers 12
Cumming School of Medicine, University of Calgary
Co-authored papers 12
Pacific Northwest National Laboratory
Co-authored papers 9
University of Washington
Co-authored papers 7
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Co-authored papers 6
Institut des Agents Infectieux, Infective Agents Institute, North Hospital Network
Co-authored papers 6
University of North Carolina
Co-authored papers 6
Pacific Northwest National Laboratory
Co-authored papers 6
Influenza Research Institute, University of Wisconsin-Madison
Co-authored papers 6
Co-authored papers 5
Influenza Research Institute, University of Wisconsin
Co-authored papers 5
Incyte Research Institute, Incyte Corporation
Co-authored papers 5
Harbin Veterinary Research Institute
Co-authored papers 5
University of North Carolina at Chapel Hill
Co-authored papers 5
Pacific Northwest National Laboratory
Co-authored papers 5
Influenza Research Institute, University of Wisconsin-Madison
Co-authored papers 5
Co-authored papers 5
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 4
Pacific Northwest National Laboratory
Co-authored papers 4
Oregon State University
Co-authored papers 4
Pacific Northwest National Laboratory
Co-authored papers 4
The University of North Carolina at Chapel Hill
Co-authored papers 4
Co-authored papers 4
Pacific Northwest National Laboratory
Co-authored papers 4
Sorbonne University INSERM
Co-authored papers 3
Pacific Northwest National Laboratory (PNNL)
Co-authored papers 3
Oregon Health & Science University, University of California Berkeley
Co-authored papers 3
Pacific Northwest National Laboratory
Co-authored papers 3